Quiñones-Álvarez MSJ, Álvarez-Hernández E, González-Chávez A, Velázquez-Moreno J

Language: Spanish
References: 17
Page: 216-220
PDF size: 75.89 Kb.

ABSTRACT

Human immunodeficiency virus (HIV) infection and systemic lupus erythematosus (SLE) have a large number of clinical and serologic features in common. The coexistence of SLE and HIV infection is still rare and there are only few reports in the literature of this association. False-positive HIV ELISA test results commonly occur in patients with systemic lupus erythematosus. The frequency reported varies between 0% and 45% and depends on the test kit used. The importance of establishing a correct diagnosis is reflected in the therapeutic decisions. We present the case of a patient with systemic lupus erythematosus and suspicion for HIV infection due to factors of risk and HIV ELISA test positive, that finally was false positive.

REFERENCES

1. Olive Marqués A. Lupus eritematoso sistémico: Epidemiología, etiopatogenia y manifestaciones clínicas. En Sociedad Española de Reumatología Manual SER de las enfermedades reumáticas. 4a ed. Madrid, España: Médica Panamericana, 2004; pp. 190-196.

2. Pisetsky DS. Systemic lupus erythematosus A. Epidemiology, pathology, and pathogenesis. In: Klippel JH. Primer on the rheumatic diseases. 12th ed. Atlanta, EUA: Arthritis Foundation, 2001; pp. 329-335.

3. Kahn JO, Walker BD. Acute human immunodeficiency virus type 1 infection. New Engl J Med 1998; 339: 33-39.

4. Palacios R, Santos J, Valdivieso P, Marquez M. Human immunodeficiency virus infection and systemic lupus erythematosus. An unusual case and review of the literature. Lupus 2002; 11: 60-63.

5. Fox RA. Isenberg DA. Human immunodeficiency virus infection in systemic lupus erythematosus. Arthritis Rheum 1997; 40: 1168-1172.

6. Sommer S, Piyadigamage A, Goodfield MJ. Systemic lupus erythematosus or infection with HIV, or both? Clin Exp Dermatol. 2004; 29: 393-395.

7. Alonso CM, Lozada CJ. Effects of IV cyclophosphamide on HIV viral replication in a patient with systemic lupus erythematosus. Clin Exp Rheumatol 2000; 18: 510-512.

8. Hazarika I, Chakravarty BP, Dutta S, Mahanta N. Emergence of manifestations of HIV infection in a case of systemic lupus erythematosus following treatment with IV cyclophosphamide. Clin Rheumatol 2006; 25: 98-100.

9. Gould T, Tikly M. Systemic lupus erythematosus in a patient with human immunodeficiency virus infection–challenges in diagnosis and management. Clin Rheumatol 2004; 23: 166-169.

10. Calza L, Manfredi R, Colangeli V, D’Antuono A, Passarini R, Chiodo F. Systemic and discoid lupus erythematosus in HIV-infected patients treated with highly active antiretroviral therapy. Int J STD AIDS 2003; 14: 356-359.

11. Chowdhry IA, Tan IJ, Mian N, Mackay M, Keiser H, Davidson A. Systemic Lupus Erythematosus presenting with features suggestive of human immunodeficiency virus infection. J Rheumatol 2005; 32: 1365-1368.

12. Marques LP, Pacheco GG, Rioja LS, Nunes SN, Velone ST, Santos OR. Can systemic lupus erythematosus be the cause of collapsing glomerulopathy? Lupus 2005; 14: 853-855.

13. Haas M Kaul S, Eustace JA. HIV-associated immune complex glomerulonephritis with “lupus-like” features: A clinicopathologic study of 14 cases. Kidney Int 2005; 67: 1381-1390.

14. Tabechian D, Pattanaik D, Zurres U, Cohn SE, Nadasdy T. Lupus-like nephritis in an HIV-positive patient: report a case and review of the literature. Clin Nephrol 2003; 60: 187-194.

15. Barthel HR, Wallace DJ. False-positive human immunodeficiency virus testing in patients with lupus erythematosus. Semin Arthritis Rheum 1993; 23: 1-7.

16. Adelman MK, Marchalonis JJ. Endogenous retroviruses in systemic lupus erythematosus: Candidate lupus viruses. Clin Immunol 2002; 102: 107-116.

17. Deas JE, Liu LG, Thompson JJ, Sander DM, Soble SS, Garry RF, Gallaher WR. Reactivity of sera from systemic lupus erythematosus and Sjögren’s syndrome patients with peptides derived from human immunodeficiency virus p24 capsid antigen. Clin Diagn Lab Immunol 1998; 5: 181-185.