Herrera GA, Peña GY, Soto MJ, León PEH, Mora DI

Language: Spanish
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Page: 1-11
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ABSTRACT

Introduction: Atherogenic indices refer to a set of biochemical indicators that, based on the relationship between lipid variables, allow predicting the risk of atherosclerotic damage.
Objective: To evaluate the usefulness of atherogenic indices in the diagnosis of subclinical atherosclerosis in patients with dyslipidemia.
Methods: A descriptive study was carried out in 812 patients with clinical diagnosis of dyslipidemia at Hermanos Ameijeiras Surgical Clinical Hospital, from 2015 to 2020.
Results: The mean age of the patients was 56.79 ± 10.24 years, the group of 60 and over predominated with 40.9% and the female sex with 73.8%. Some type of obesity was present in 61.2% of the patients. The presence of hypertension and tobacco consumption affect 52% and 24.6% of the population studied, respectively. 74.8% (607 cases) were classified as medium cardiovascular risk according to Framingham criteria, while 12.9% were classified as high risk. Three hundred twenty three (39.8%) patients with subclinical atherosclerosis were identified. The differences in the mean values of the atherogenic indices between the groups with subclinical atherosclerosis were statistically significant for the total C/HDLc and LDLc/HDLc indices (p<0.05). In the multivariate analysis, the indices associated with the risk of subclinical atherosclerosis were the ratio of Total C/HDLc (R=1.11) and LDLc/HDLc (R=1.12) (p<0.05).
Conclusions: The atherogenic indices are useful in the diagnosis of subclinical atherosclerosis; cCtotal/cHDL and cLDL/cHDL ratios are those that are significantly associated with the probability of carotid atherosclerotic damage.