2024, Number 4
Renal carcinoma with synchronous and contralateral upper urothelial carcinoma. Clinical case presentation
Language: Spanish
References: 10
Page: 1-8
PDF size: 406.56 Kb.
ABSTRACT
Clinical case presentation: A 71-year-old male patient presented with anemic syndrome and macroscopic hematuria. Utrotomography showed left renal cancer and urothelial tumor of the right upper urinary tract of synchronous appearance; Nephroureterectomy with bladder cuff on the right side and partial left nephrectomy were performed, both laparoscopically at the same surgical time.Relevance: Renal carcinoma represents 2-3 % of primary urological cancers, while upper tract urothelial carcinoma is a rare uroepithelial tumor whose incidence reaches 5-10 % of all urothelial carcinomas. While it is rare for urologic tumors to occur together, it is even rarer to find renal carcinoma combined with upper tract urothelial carcinoma; It is estimated that it occurs in 1.1 % of cases.
Clinical implications: For the treatment of renal cancer combined with upper tract urothelial cancer, radical nephroureterectomy with contralateral partial nephrectomy remains the best treatment option showing good oncological results.
Conclusions: The incidence of synchronous tumors increases simultaneously with the increase in the incidence of genitourinary tumors. Treatment represents a challenge for the urologist and must be individualized according to the patient’s characteristics.
REFERENCES
Hu M, Pan D, Wei Y, Ye L. Atypical RecurrentRenal Cell Carcinoma of the Ipsilateral UreterShowing Typical Symptoms of Upper UrinaryTract Urothelial Carcinoma: A Case Reportand Literature Review. Archivos Espanoles DeUrologia. 2023;76(3): 238–244. https://doi.org/10.56434/j.arch.esp.urol.20237603.27.
Mazzaschi G, Giudice GC, Corianò M,Campobasso D, Perrone F, Maffezzoli M, etal. Upper Tract Urinary Carcinoma: A UniqueImmuno-Molecular Entity and a ClinicalChallenge in the Current Therapeutic Scenario.Technology in Cancer Research & Treatment.2023;22: 15330338231159753. https://doi.org/10.1177/15330338231159753.