2003, Number 3
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Alerg Asma Inmunol Pediatr 2003; 12 (3)
Immunology in Nobel prizes from medicine
Aviña FJA, Hernández ADA
Language: Spanish
References: 20
Page: 89-91
PDF size: 75.44 Kb.
ABSTRACT
The immunology is the medical branch that more Nobel prizes from Medicine and Physiology has obtained, initiating with the first award in 1901 to Behring by his studies in seric therapy until the most recent in the year 2002 to Brenner and Horvitz (USA) and Sulston (Great Britain) by the studies made in worm C. elegans that allowed the understanding of the genetic control of the programmed cellular death: apoptosis. The Nobel Prize has influenced in the great development of the immunology throughout the XX century that has taken to great profits in the area of the allergic, immunological diseases and in the success of the transplants in the human being. This historical revision offers a panoramic of the great profits that have been obtained and the scientific changes in the fundamental bases of the Immunology.
REFERENCES
Enders JF. Remarks on oncogenic virus-cell relationships. Proc Natl Cancer Conf 1964; 5: 725-732.
Robbins FC, Woods WA, Johnson RT, Hostetler OD, Lepow ML. Immunofluorescent studies on rubella-infected tissue cultures and human tissues. J Immunol 1966; 96(2): 253-260.
Weller TH, Alford CA, Neva FA. Changing epidemiologic concepts of rubella, with particular reference to unique characteristics of the congenital infection. Yale J Biol Med 1965; 37(6): 455-472.
Medawar PB, Gibson T. Modern trends in plastic surgery. Homografts. Mod Trends Plast Surg 1966; 2: 1-15.
Edelman GM, Gally JA. The genetic control of immunoglobulin synthesis. Annu Rev Genet 1972; 6: 1-46.
Porter RR, Fleet GW, Knowler JR. The antibody binding site. Labelling of a specific antibody against the photo-precursor of an aryl nitrene. Biochem J 1972; 128(3): 499-508.
Benacerraf B, Greene MI, Sy MS, Nisonoff A. The genetic and cellular basis of antigen and receptor stimulated regulation. Mol Immunol 1980; 17(7): 857-866.
Snell GD. Recent advances in histocompatibility immunogenetics. Adv Genet 1979; 20: 291-355.
Dausset J, Fradelizi D, Gluckman E, Wiels J, Sasportes M et al. Functional study and detection of HLA-D products on fractionated human bone marrow cells. Tissue Antigens 1980; 15(2): 161-172.
Jerne NK. Idiotypic networks and other preconceived ideas. Immunol Rev 1984; 79: 5-24.
Kohler G, Baumann B, Iglesias A, McCubrey J, Potash MJ et al. Different ways to modify monoclonal antibodies. Med Oncol Tumor Pharmacother 1984; 1(4): 227-233.
Milstein C, Calabi F, Martin RH. Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens. Proc Natl Acad Sci USA 1986; 83(23): 9154-9158.
Tonegawa S, Maeda K, Nakanishi N, Rogers BL, Haser WG et al. Expression of the T-cell receptor gamma-chain gene products on the surface of peripheral T cells and T-cell blasts generated by allogeneic mixed lymphocyte reaction. Proc Natl Acad Sci USA 1987; 84(18): 6536-6540.
Thomas ED. Landmarks in the development of hematopoietic cell transplantation. World J Surg 2000; 24(7): 815-818.
Murray JE. Renal transplantation before Starzl. Transplant Proc 1988; 20(1 Suppl. 1): 339-342.
Doherty PC, Lockey TD, Surman S, Brown S, Slobod KS et al. A five-residue HIV envelope helper T cell determinant: does this peptide-MHC interaction leave the binding groove half empty? AIDS Res Hum Retroviruses 2002; 18(15): 1141-1144.
Zinkernagel RM. On cross-priming of MHC class I-specific CTL: rule or exception? Eur J Immunol 2002; 32(9): 2385-2392.
Brenner S. The worm’s turn. Curr Biol 2002; 12(21): R 713.
Horvitz RH, Hosler BA, Nicholson GA, 19. Sapp PC, Chin W et al. Three novel mutations and two variants in the gene for Cu/Zn superoxide dismutase in familial amyotrophic lateral sclerosis. Neuromuscul Disord 1996; 6(5): 361-366.
Sulston JE, Hall N, Pain A, Berruman M, Churcher C et al. Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Nature 2002; 419 (6906): 527-531.