2024, Number 3
<< Back Next >>
Enf Infec Microbiol 2024; 44 (3)
Avian influenza virus A (H5N1): a potential new threat
Ospina GJM, Revelo-Cueva MC, Cardona MWD
Language: Spanish
References: 43
Page: 112-118
PDF size: 210.07 Kb.
ABSTRACT
The highly pathogenic avian influenza virus (AIV) H5N1 is a global concern due to its ability to cause epidemics in
humans with a high mortality rate. The literature review undertaken aims to describe general and epidemiological
aspects of the H5N1 AIV, as well as to understand the current context of the infection. It starts with the description
of AIVS, their structural proteins and types of strains. The origin of H5N1 is raised through mutations of structural
proteins that have allowed its adaptation and transmission between species; generating outbreaks in humans
since 1997. A chronological review of the cases reported in Asia, Europe and Africa is made and it is highlighted
that in North America and South America, cases have been reported in birds, humans and mammals. The review
shows the importance of continuous surveillance and research to prevent future outbreaks and develop effective
control strategies, which include preventive and therapeutic measures.
REFERENCES
Li, Y.T., Linster, M., Mendenhall, I.H., Su, Y.C.F. y Smith,G.J.D., “Avian influenza viruses in humans: lessons frompast outbreaks”, British Medical Bulletin, 2019, 132(1): 81-95. Disponible en: https://doi.org/10.1093/bmb/ldz036.
Chan, P.K.S., “Outbreak of avian influenza a (h5n1) virusinfection in Hong Kong in 1997”, Clinical Infectious Diseases,2002, 34 (Supplement_2): S58-S64. Disponibleen: https://doi.org/10.1086/338820.
Tong, S., Zhu, X., Li, Y., Shi, M., Zhang, J., Bourgeois,M. et al., “New world bats harbor diverse influenza aviruses”, plos Pathogens, 2013, 9 (10): e1003657. Disponibleen: https://doi.org/10.1371/journal.ppat.1003657.
Fodor, E. y Te Velthuis, A.J.W., “Structure and functionof the influenza virus transcription and replication machinery”,Cold Spring Harbor Perspectives in Medicine,2020, 10 (9). Disponible en: https://doi.org/10.1101/cshperspect.a038398.
Webster, R.G., Bean, W.J., Gorman, O.T., Chambers,T.M. y Kawaoka, Y., “Evolution and ecology of influenzaa viruses”, Microbiological Reviews, 1992, 56 (1):152-179. Disponible en: https://10.0.4.104/mr.56.1.152-179.1992.
Su, S., Fu, X., Li, G., Kerlin, F. y Veit, M., “Novel influenzad virus: epidemiology, pathology, evolution and biologicalcharacteristics”, Virulence, 2017, 8 (8): 1580-1591.Disponible en: https://doi.org/10.1080/21505594.2017.1365216.
Ramey, A.M., Hill, N.J., DeLiberto, T.J., Gibbs, S.E.J., CamilleHopkins, M., Lang, A.S. et al., “Highly pathogenicavian influenza is an emerging disease threat to wildbirds in North America”, The Journal of Wildlife Management,2022, 86 (2): e22171. Disponible en: https://doi.org/10.1002/jwmg.22171.
Verhagen, J.H., Fouchier, R.A.M. y Lewis, N., “Highlypathogenic avian influenza viruses at the wild-domesticbird interface in Europe: future directions for researchand surveillance”, Viruses, 2021, 13 (2): 212. Disponibleen: https://doi.org/10.3390/v13020212.
Yamaji, R., Saad, M.D., Davis, C.T., Swayne, D.E., Wang,D., Wong, F.Y.K. et al., “Pandemic potential of highly pathogenicavian influenza clade 2.3. 4.4 a (h5) viruses”,Reviews in Medical Virology, 2020, 30 (3): e2099. Disponibleen: https://doi.org/10.1002/rmv.2099.
Evolution Working G., “Toward a unified nomenclaturesystem for highly pathogenic avian influenza virus(h5n1)”, Emerging Infectious Diseases, 2008, 14 (7): e1.Disponible en: https://doi.org/10.3201/eid1407.071681.
Li, Y., Li, M., Li, Y., Tian, J., Bai, X., Yang, C. et al., “Outbreaksof highly pathogenic avian influenza (h5n6)virus subclade 2.3. 4.4 h in swans, Xinjiang, WesternChina, 2020”, Emerging Infectious Diseases, 2020,26 (12): 2956. Disponible en: https://doi.org/10.3201/eid2612.201201.
Long, J.S., Mistry, B., Haslam, S.M. y Barclay, W.S.,“Host and viral determinants of influenza a virus speciesspecificity”, Nature Reviews Microbiology, 2019, 17 (2):67-81. Disponible en: https://doi.org/10.1038/s41579-018-0115-z.
Peacock, T.P., Swann, O.C., Salvesen, H.A., Staller, E., Leung,P.B., Goldhill, D.H. et al., “Swine anp32a supports avianinfluenza virus polymerase”, Journal of Virology, 2020,94 (12):10-11. Disponible en: https://doi.org/10.1128/JVI.00132-20.
Ito, T., Couceiro, J.N.S.S., Kelm, S., Baum, L.G., Krauss,S., Castrucci, M.R. et al., “Molecular basis for the generationin pigs of influenza a viruses with pandemicpotential”, Journal of Virology, 1998, 72 (9): 7367-7373.Disponible en: https://doi.org/10.1128/JVI.72.9.7367-7373.1998.
Ma, W., Kahn, R.E. y Richt, J.A., “The pig as a mixingvessel for influenza viruses: human and veterinary implications”,Journal of Molecular and Genetic Medicine:An International Journal of Biomedical Research, 2009,3 (1): 158.
Petrova, V.N. y Russell, C.A., “The evolution of seasonalinfluenza viruses”, Nature Reviews Microbiology, 2018,16 (1): 47-60. Disponible en: https://doi.org/10.1038/nrmicro.2017.118.
Centros para el Control y la Prevención de Enfermedades(cdc), “Casos en seres humanos de infección porel virus a (h5n1) de la forma altamente patógena de lainfluenza aviar (hpai h5n1) anteriores notificados a nivelmundial por país, 1997-2023”, 2023.
Bridges, C.B., Lim, W., Hu-Primmer, J., Sims, L., Fukuda,K., Mak, K.H. et al., “Risk of influenza a (h5n1) infectionamong poultry workers, Hong Kong, 1997-1998”, TheJournal of Infectious Diseases, 2002, 185 (8): 1005-1010. Disponible en: https://doi.org/10.1086/340044.
Whelan, M.G., Le, Q.B. y Hall, D.C., “The impact of experiencesand perceptions of highly pathogenic avianinfluenza (hpai) on water-related biosecurity behaviour inrural Vietnam”, Risk Analysis, 2021, 41 (12): 2240-2265.Disponible en: https://doi.org/10.1111/risa.13753.
Tiensin, T., Chaitaweesub, P., Songserm, T., Chaisingh,A., Hoonsuwan, W., Buranathai, C. et al., “Highly pathogenicavian influenza h5n1, Thailand, 2004”, EmergingInfectious Diseases, 2005, 11 (11): 1664. Disponible en:https://doi.org/10.3201/eid1111.050608.
Zhao, Z.-M., Shortridge, K.F., García, M., Guan, Y. y Wan,X.-F., “Genotypic diversity of h5n1 highly pathogenicavian influenza viruses”, Journal of General Virology,2008, 89 (9): 2182-2193. Disponible en: https://doi.org/10.1099/vir.0.2008/001875-0.
World Health Organization, “Cumulative number of confirmedhuman cases for avian influenza a (h5n1) reportedto who, 2003-2023”, 2023.
Cattoli, G., Fusaro, A., Monne, I. y Capua, I., “h5n1 virusevolution in Europe: an updated overview”, Viruses,2009, 1 (3): 1351-1362. Disponible en: https://doi.org/10.3390/v1031351.
Aznar, E., Casas, I., Praetorius, A.G., Ramos, M.J.R.,Pozo, F., Moros, M.J.S. et al., “Influenza a (h5n1) detectionin two asymptomatic poultry farm workers inSpain, September to October 2022: suspected environmentalcontamination”, Eurosurveillance, 2023, 28 (8):2300107. Disponible en: https://doi.org/10.2807/1560-7917.ES.2023.28.8.2300107.
Yang, P., Pang, X., Zhang, Y., Wang, X., Zhang, D., Qian,H. et al., “Illicit poultry selling was probably the sourceof infection of the first h5n1 case in the Americasimported from Beijing”, Journal of Infection, 2014, 68(5): 505-506. Disponible en: https://doi.org/10.1016/j.jinf.2014.01.010.
Torchetti, M.K., Killian, M.L., Dusek, R.J., Pedersen, J.C.,Hines, N., Bodenstein, B. et al., “Novel h5 clade 2.3.4.4 reassortant (h5n1) virus from a green-winged tealin Washington, USA”, Genome Announcements, 2015,3 (2): 10-1128. Disponible en: https://doi.org/10.1128/genomeA.00195-15.
Bevins, S.N., Shriner, S.A., Cumbee Jr, J.C., Dilione, K.E.,Douglass, K.E., Ellis, J.W. et al., “Intercontinental movementof highly pathogenic avian influenza a (h5n1) clade2.3. 4.4 virus to the United States, 2021”, EmergingInfectious Diseases, 2022, 28 (5): 1006. Disponible en:https://doi.org/ 10.3201/eid2805.220318.
Animal and Plant Health Inspection Service, “2022-2024Confirmations of highly pathogenic avian influenza incommercial and backyard flocks”, 2024.
Centers for Disease Control and Prevention, “U.S. caseof human avian influenza a (h5) virus reported”, 2022.
Animal and Plant Health Inspection Service, “2022-2024Detections of highly pathogenic avian influenza in wildbirds”, 2024.
World Health Organization, “Genetic and antigeniccharacteristics of zoonotic influenza a viruses and developmentof candidate vaccine viruses for pandemicpreparedness”, 2023.
Organización Panamericana de la Salud, “Actualizaciónepidemiológica: brotes de influenza aviar causados porinfluenza a (h5n1) en la región de las Américas”, 2023.
World Health Organization, “Human infection caused byavian influenza a (h5), Ecuador”, 2023.
Centros para el Control y la Prevención de Enfermedades,“Infección en seres humanos por el virus a (h5n1)de la influenza aviar altamente patógena en Chile”, 2023.
Centros para el Control y la Prevención de Enfermedades,“Informe técnico: virus de la influenza aviar a (h5n1)altamente patógena”, 2023.
Animal and Plant Health Inspection Service, “2022-2024Detections of highly pathogenic avian influenza in mammals”,2022.
Agüero, M., Monne, I., Sánchez, A., Zecchin, B., Fusaro,A., Ruano, M.J. et al., “Highly pathogenic avian influenzaa (h5n1) virus infection in farmed minks, Spain,October 2022”, Eurosurveillance, 2023, 28 (3): 2300001.Disponible en: https://doi.org/10.2807/1560-7917.ES.2023.28.3.2300001.
Bogs, J., Kalthoff, D., Veits, J., Pavlova, S., Schwemmle,M., Mänz, B. et al., “Reversion of pb2-627e to-627K duringreplication of an h5n1 clade 2.2 virus in mammalianhosts depends on the origin of the nucleoprotein”, Journalof Virology, 2011, 85 (20): 10691-10698. Disponibleen: https://doi.org/10.1128/JVI.00786-11.
Gabriel, G., Czudai-Matwich, V. y Klenk, H.-D., “Adaptivemutations in the h5n1 polymerase complex”, Virus Research,2013, 178 (1): 53-62. Disponible en: https://doi.org/10.1016/j.virusres.2013.05.010.
Kandeil, A., Patton, C., Jones, J.C., Jeevan, T., Harrington,W.N., Trifkovic, S. et al., “Rapid evolution of a (h5n1)influenza viruses after intercontinental spread to NorthAmerica”, Nature Communications, 2023, 14 (1): 3082.Disponible en: https://doi.org/10.1038/s41467-023-38415-7.
Centros para el Control y la Prevención de Enfermedades,“Infecciones por virus de la influenza aviar en humanos”,2022.
Centros para el Control y la Prevención de Enfermedades,“Prevención y tratamiento con antivirales de infeccionespor el virus de la influenza aviar en personas”, 2022.
Reece, P.A., “Treatment options for h5n1: lessons learnedfrom the h1n1 pandemic”, Postgraduate Medicine,2010, 122 (5): 134-141. Disponible en: https://doi.org/10.3810/pgm.2010.09.2210.