2024, Number 3
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Dermatología Cosmética, Médica y Quirúrgica 2024; 22 (3)
Amorolfine: indications of a classic antifungal
Valdez MA, Arenas GR
Language: Spanish
References: 17
Page: 273-278
PDF size: 210.62 Kb.
ABSTRACT
Superficial mycoses are fungal infections that affect the externa
layers of the skin, including hair and nails, and are caused by dermatophytes,
yeasts, and non-dermatophyte molds.
Managing superficial mycoses is mandatory for dermatologists
and gps. Regarding amorolfine, a morpholine derivative,
inhibits ergosterol biosynthesis and provides effectiveness and
safety in the treatment of ringworm and onychomycosis.
We performed a literature review about the chemical profile
of amorolfine, clinical applications, efficacy, and market availability.
Amorolfine remains a valuable tool in treating superficial mycoses,
offering flexibility and effectiveness in monotherapy or
combination with systemic treatments. Its proper application can
optimize results and improve the quality of life of treated patients.
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