2022, Number 2
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CorSalud 2022; 14 (2)
Brugada syndrome in pregnancy: A case report
Yllodo CA, Peña LE, Leyva PLV, Zayas FE, Román RPA, Vasallo PR
Language: Spanish
References: 22
Page: 199-203
PDF size: 301.42 Kb.
ABSTRACT
Brugada syndrome is a hereditary cardiac channelopathy that predisposes to ven-tricular tachyarrhythmias and, as a consequence, to sudden death. Its diagnosis is based on a specific electrocardiographic pattern. There are few reports on this syndrome in pregnancy. This article presents the case of a 26-year-old pregnant woman with implantable cardioverter-defibrillator due to this cause, who was referred to the National Department of Heart Disease in Pregnancy where she remained under monitoring, stable, without any complication. There are contro-versies about whether or not the increase in female hormones is a protective fac-tor in pregnant women with Brugada syndrome. Despite the generally benign course of this disease during pregnancy, there are still important questions to be clarified. The follow-up of patients is considered essential to guarantee maternal-fetal well-being.
REFERENCES
Brugada J, Campuzano O, Arbelo E, Sarquella-Brugada G, Brugada R. Present Status of Brugada Syndrome: JACC State-of-the-Art Review. J Am Coll Cardiol. 2018;72(9):1046-59. [DOI]
Wu W, Tian L, Ke J, Sun Y, Wu R, Zhu J, et al. Risk factors for cardiac events in patients with Brugada syndrome: A PRISMA-compliant meta-analysis and systematic review. Medicine (Balti-more) [Internet]. 2016 [citado 2 Ago 2021];95(30): e4214. Disponible en:https://doi. org/10. 1097/md. 0000000000004214
Mont-Girbau L, Brugada J. Arritmias cardíacas. En: Rozman C, Cardellach F, eds. Farreras Medi-cina Interna. Vol 1. 19ª ed. España: Elsevier; 2020. p. 435-62.
Olguin JE, Tomaselli GF, Zipes DP. Arritmias ven-triculares. En: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, eds. Braunwald Tratado de Cardiología. 11ª ed. España: Elsevier; 2019. p. 753-71.
Sieira J, Brugada P. The definition of the Brugada syndrome. Eur Heart J. 2017;38(40):3029-34. [DOI]
Benito B, Brugada J, Brugada R, Brugada P. Sín-drome de Brugada. Rev Esp Cardiol. 2009;62(11): 1297-315. [DOI]
Brugada R, Campuzano O, Sarquella-Brugada G, Brugada J, Brugada P. Brugada syndrome. Meth-odist Debakey Cardiovasc J. 2014;10(1):25-8. [DOI]
Janin A, Bessière F, Georgescu T, Chanavat V, Chevalier P, Millat G. TRPM4 mutations to cause autosomal recessive and not autosomal dominant Brugada type 1 syndrome. Eur J Med Genet [In-ternet]. 2019 [citado 8 Ago 2021];62(6):103527. Dis-ponible en:https://doi. org/10. 1016/j. ejmg. 2018. 08. 008
Prochnau D, Figulla HR, Surber R. First clinical manifestation of Brugada syndrome during preg-nancy. Herzschrittmacherther Elektrophysiol. 2013;24(3):194-6. [DOI]
Pappone C, Santinelli V. Brugada Syndrome: Pro-gress in Diagnosis and Management. Arrhythm Electrophysiol Rev. 2019;8(1):13-8. [DOI]
Ideishi A, Ogawa M, Nagata Y, Idemoto Y, Komaki T, Morii J, et al. Pregnancy May Affect the Atten-uation of an ST Segment Elevation in the Right Precordial Leads: A Female Patient with Brugada Syndrome. Intern Med. 2019;58(21):3099-102. [DOI]
Bramall J, Combeer A, Springett J, Wendler R. Caesarean section for twin pregnancy in a partu-rient with Brugada syndrome. Int J Obstet Anesth. 2011;20(2):181-4. [DOI]
Sharif-Kazemi MB, Emkanjoo Z, Tavoosi A, Kafi M, Kheirkhah J, Alizadeh A, et al. Electrical storm in Brugada syndrome during pregnancy. Pacing Clin Electrophysiol. 2011;34(2):18-21. [DOI]
Guía ESC 2015 sobre el tratamiento de pacientescon arritmiasventriculares y prevención de la muerte súbita cardiaca. Rev Esp Cardiol. 2016; 69(2):176. e1-176. [DOI]
Benito B, Berruezo A. Síndrome de Brugada y embarazo: indagando en el papel de las hormo-nas sexuales en las canalopatías iónicas. Rev Esp Cardiol. 2014;67(3):165-7. [DOI]
Song M, Helguera G, Eghbali M, Zhu N, Zarei MM, Olcese R, et al. Remodeling of Kv4. 3 potassium channel gene expression under the control of sex hormones. J Biol Chem. 2001;276(34):31883-90. [DOI]
Múnera-Echeverri AG. Enfermedad cardíaca y embarazo. Rev Colomb Cardiol. 2018;25(S1):49-58. [DOI]
Rodríguez-Mañero M, Casado-Arroyo R, Sarkozy A, Leysen E, Sieira JA, Namdar M, et al. Trascen-dencia clínica del embarazo en el síndrome de Brugada. Rev Esp Cardiol. 2014;67(3):176-80. [DOI]
Priori SG, Napolitano C, Giordano U, Collisani G, Memmi M. Brugada syndrome and sudden cardi-ac death in children. Lancet. 2000;355(9206):808-9. [DOI]
Pagel PS, Lilly RE, Nicolosi AC. Use of ECMO to temporize circulatory instability during severe Brugada electrical storm. Ann Thorac Surg. 2009; 88(3):982-3. [DOI]
Schwartz PJ, Priori SG, Dumaine R, Napolitano C, Antzelevitch C, Stramba-Badiale M, et al. A mo-lecular link between the sudden infant death syndrome and the long-QT syndrome. N Engl J Med. 2000;343(4):262-7. [DOI]
Kiekebusch Hurel G, Baez Aguirre M, Spralja Sa-talic B, Salinas Chau A, Barahona Ruiz W. Flutter atrial fetal en madre portadora de síndrome de Brugada: Caso Clínico. CIMEL. 2009;14(1):55-9.