2024, Number 5
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Arch Med Fam 2024; 26 (5)
Metabolic Syndrome as a Risk Factor for Arterial Stiffness
Rubio-Guerra AF, Guerrero GC, Benítez-Maldonado DR, Narváez-Rivera JL, Vargas-Ayala G
Language: Spanish
References: 13
Page: 243-246
PDF size: 188.69 Kb.
ABSTRACT
Objective: To evaluate the risk of arterial wall stiffnes
in patients with metabolic syndrome.
Methods:
150 patients were included, in whom the PWV pulse
wave velocity was determined with an Arteriograph
device, a PWV ≤ 9 m/S was considered normal.
The diagnosis of metabolic syndrome was made with
the criteria of the International Diabetes Federation.
The statistical methods used were odds ratio and
Mann-Whitney U.
Results: We found PWV › 9 m/S
in 79 patients, 69 with metabolic syndrome. We diagnosed
metabolic syndrome in 105 (70%) subjects, the
odds ratio for presenting pulse wave velocity › 9 m/s
in patients with metabolic syndrome was 6.7 (95 CI
2.98 to 15.08, p › 0.0001).
Conclusions: Metabolic syndrome
increases the risk of arterial stiffness, which
increases the cardiovascular risk of these patients.
The measurement of PWV is a safe tool that provides
useful information in the global assessment of these
patients, and should be part of the comprehensive
study of patients with metabolic syndrome.
REFERENCES
Guerrero-García C, Rubio-Guerra AF, Arana-Pazos KC,Maceda-Serrano A, Narváez-Rivera JL, Meneses-AceroI, Vargas Ayala G. Correlación entre el grosor intimamedia con la velocidad de la onda del pulso, y el índicebrazo tobillo en sujetos con Síndrome metabólico.Arch Med Fam 2019;21:43-47
Rubio-Guerra AF, Durán-Salgado MB. AntihypertensiveTreatment and Vascular Extracellular Matrix Remodeling.Cardiology 2014;127:245-246.
Rubio-Guerra AF, Narváez-Rivera Jl, Benítez-MaldonadoDR, Guerrero-García C, Arana-Pazos KC, Vargas-AyalaG. Correlación entre niveles de ácido úrico y velocidadde la onda del pulso en sujetos con síndromemetabólico. Nefro Latinoam 2019;16:33-38
Bonarjee VVS. Arterial Stiffness: A Prognostic Markerin Coronary Heart Disease. Available Methods andClinical Application. Front Cardiovasc Med. 2018;5:64.
Rubio-Guerra AF, Durán-Salgado MB. Insulina, sistemarenina angiotensina aldosterona y disfunción endotelial.Rev Med IMSS 2011;49:581-584
Ring M, Eriksson MJ, Zierath JR, Caidahl K. Arterialstiffness estimation in healthy subjects: a validationof oscillometric (Arteriograph) and tonometric (SphygmoCor)techniques. Hypertens Res. 2014;37:999-1007.
Alberti KG, Eckel RH, Grundy SM, et al. InternationalDiabetes Federation Task Force on Epidemiology andPrevention; National Heart, Lung, and Blood Institute;American Heart Association; World Heart Federation;International Atherosclerosis Society; InternationalAssociation for the Study of Obesity. Harmonizingthe metabolic syndrome: a joint interim statement ofthe International Diabetes Federation Task Force onEpidemiology and Prevention; National Heart, Lung,and Blood Institute; American Heart Association;World Heart Federation; International AtherosclerosisSociety; and International Association for the Study ofObesity. Circulation 2009;8 120: 1640-5.
Rubio-Guerra AF, Cabrera-Miranda LJ, Vargas-Robles H,Maceda-Serrano A, Lozano-Nuevo JJ, Escalante-AcostaBA. Correlation between levels of circulating adipokinesand adiponectin/resistin index with carotid intima-media thickness in hypertensive type 2 diabeticpatients. Cardiology 2013;125(3):150-153.
Chen MC, Lee CJ, Yang CF, Chen YC, Wang JH, Hsu BG.Low serum adiponectin level is associated with metabolicsyndrome and is an independent marker of peripheralarterial stiffness in hypertensive patients. DiabetolMetab Syndr. 2017;9:49
Lopes-Vicente WRP, Rodrigues S, Cepeda FX, et al.Arterial stiffness and its association with clusteringof metabolic syndrome risk factors. Diabetol MetabSyndr. 2017;9:87
Aroor AR, Jia G, Sowers JR. Cellular mechanisms underlyingobesity-induced arterial stiffness. Am J PhysiolRegul Integr Comp Physiol. 2018;314(3):R387-R398
Desai N, Venkatesh CR, Koregol P. Arterial stiffness – Ameasurable vascular marker in clinical practice. APIK JInt Med 2021;9:146-52.
Upadhya B, Pajewski NM, Rocco MV, et al. Effect ofIntensive Blood Pressure Control on Aortic Stiffnessin the SPRINT-HEART. Hypertension. 2021;77(5):1571-1580.