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2022, Number 2

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Correo Científico Médico 2022; 26 (2)

COVID-19 in pregnant women

Serrano GNB, Bermúdez GAJ, Fernández TM

Language: Spanish
References: 38
Page:
PDF size: 415.13 Kb.


ABSTRACT

Pregnancy increases the risk of severe COVID-19 and pregnant women infected with SARS-CoV-2 have more obstetric and perinatal complications than uninfected pregnant women. The objectives of this literature review were to describe gestational changes that favor SARS-CoV-2 infection, clinical manifestations, maternal-fetal complications, and the role of vaccination. The search was carried out at: Google Scholar (https://scholar.google.com.cu), PubMed Central (https://www.ncbi.nlm.nih.gov/pmc), SciELO (https://scielo.org/es) and Infomed (http://www.bvscuba.sld.cu/clasificacion-de-revista/revistas-cubanas) with the descriptors COVID-19, SARS-CoV-2 and pregnancy. Among the adaptations of pregnancy that favor infection are disruptions in innate and adaptive immunity, changes in the respiratory system and coagulation response. Pregnant women are at an increased risk of severe disease and the main symptoms of COVID-19 are fever, cough, fatigue, dyspnea and may present complications such as miscarriage, cesarean section, preterm delivery and preeclampsia. Anti-COVID-19 vaccination is an effective preventive method.


REFERENCES

  1. Wang CL, Liu YY, Wu CH, Wang CY, Wang CH, Long CY. Impact of COVID-19 on Pregnancy. Int J Med Sci.2021[citado 09/11/2021]; 18(3): 763-767. Disponible en:https://doi.org/10.7150/ijms.49923

  2. WHO. WHO Coronavirus (COVID-19) Dashboard. Suiza,Ginebra:WHO;10/11/2021[citado 25/02/2022].Disponible en: https://covid19.who.int

  3. Razzaghi H, Meghani M, Pingali C, Crane B, Naleway A, Weintraub E, et al.COVID-19 Vaccination Coverage Among Pregnant Women During Pregnancy - Eight Integrated Health Care Organizations, United States, December 14, 2020-May 8, 2021. MMWR Morb Mortal Wkly Rep. 2021[citado 09/11/2021];70(24):895-899. Disponible en:https://www.cdc.gov/mmwr/volumes/70/wr/mm7024e2.htm

  4. Naves do Amaral W ,Leão de Moraes C, Dos Santos Rodrigues AP,Noll M,Tacon Arruda J, Carolina Rodrigues Mendonça C. Maternal Coronavirus Infections and Neonates Born to Mothers with SARS-CoV-2: A Systematic Review. Healthcare (Basel). 2020 [citado 09/11/2021];8(4):511. Disponible en:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712854/pdf/healthcare-08-00511.pdf

  5. Adhikari EH, Spong CY. COVID-19 Vaccination in Pregnant and Lactating Women. JAMA. 2021[citado 09/10/2021];325(11):1039-1040.Disponible en:https://jamanetwork.com/journals/jama/article-abstract/2776449

  6. Perdigón Portieles CJ, Hernández Toboso ML. Embarazo en tiempos de COVID-19, un acercamiento a la evidencia científica. Rev Cubana Obstet Ginecol. 2020[citado 09/11/2021];46(2). Disponible en:http://revginecobstetricia.sld.cu/index.php/gin/article/view/634

  7. 7.Di Mascio D , Buca D, Berghella V, Khalil A ,Rizzo G, Odibo A. Counseling in maternal-fetal medicine: SARS-CoV-2 infection in pregnancy. Ultrasound Obstet Gynecol. 2021[citado 09/11/2021];57(5):687-697. Disponible en:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251147/pdf/UOG-57-687.pdf

  8. Madjunkov M, Dviri M, Librach C. A comprehensive review of the impact of COVID-19 on human reproductive biology, assisted reproduction care and pregnancy: a Canadian perspective. J Ovarian Res. 2020[citado 09/11/2021];13:140. Disponible en:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694590/

  9. Boushra MN, Koyfman A, Long B. COVID-19 in pregnancy and the puerperium: A review for emergency physicians. Am J Emerg Med. 2021[citado 09/11/2021]; 40: 193-198. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S0735675720309517?via%3Dihub

  10. Mirbeyk M, Saghazadeh A, Rezaei N. A systematic review of pregnant women with COVID-19 and their neonates. Arch Gynecol Obstet. 2021 [citado 09/11/2021]: 304(1):5-38. Disponible en: https://link.springer.com/article/10.1007/s00404-021-06049-z

  11. Phoswa WN, Khaliq OP. Is pregnancy a risk factor of COVID-19? Eur J Obstet Gynecol Reprod Biol. 2020[citado 09/11/2021];252:605-609. Disponible en:https://www.sciencedirect.com/science/article/abs/pii/S0301211520304334?via%3Dihub

  12. Tolu LB, Ezeh A, Feyissa GT. Vertical transmission of Severe Acute Respiratory Syndrome Coronavirus 2: A scoping review. PLoS One.2021[citado 09/11/2021]; 16(4):0250196. Disponible en: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0250196

  13. Auriti C, De Rose DU, Mondì V, Stolfi I, Tzialla C. Neonatal SARS-CoV-2 Infection: Practical Tips. Pathogens. 2021 [citado 09/11/2021]; 10(5):611. Disponible en:https://doi.org/10.3390/pathogens10050611

  14. Vouga M, Favre G , Martinez Perez O , Pomar L , Forcen Acebal L, Abascal Saiz A, et al. Maternal outcomes and risk factors for COVID-19 severity among pregnant women. Sci Rep. 2021[citado 09/11/2021];11(1):13898. Disponible en:https://www.nature.com/articles/s41598-021-92357-y.pdf

  15. Wei SQ, Bilodeau Bertrand M, Liu S, Auger N. The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis. CMAJ. 2021 [citado 09/11/2021];193(16):540-548.Disponible en:https://www.cmaj.ca/content/cmaj/193/16/E540.full.pdf

  16. Savirón Cornudella R, Villalba A, Esteban LM, Tajada M, Rodríguez Solanilla B, Andeyro Garcia M, et al. Screening of severe acute respiratory syndrome coronavirus-2 infection during labor and delivery using polymerase chain reaction and immunoglobulin testing. Life Sci. 2021[citado 09/11/2021]; 271: 119200. Disponible en:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871853/pdf/main.pdf

  17. Principi N, Esposito S. Is the Immunization of Pregnant Women against COVID-19 Justified?.Vaccines(Basel). 2021 [citado 09/11/2021];9(9):970. Disponible en:https://www.mdpi.com/2076-393X/9/9/970

  18. Male V. Are COVID-19 vaccines safe in pregnancy?. Nat Rev Immunol. 2021[citado 09/11/2021];21:200-201. Disponible en: https://doi.org/10.1038/s41577-021-00525-y

  19. Rasmussen SA, Smulian JC, Lednicky JA, Wen TS, Jamieson DJ. Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know. Am J Obstet Gynecol. 2020[citado 09/11/2021]; 222 (5): 415-426. Disponible en: https://doi.org/10.1016/j.ajog.2020.02.017

  20. Díaz Armas MT, Sánchez Artigas R, Matute Respo TZ, Llumiquinga Achi RA. Proteína de la espícula del virus SARS-CoV-2 y su relación con la enzima convertidora de angiotensina-2. Rev Inf Cient.2021 [citado 09/11/2021];100 (5) Disponible en:http://revinfcientifica.sld.cu/index.php/ric/article/view/3633

  21. Eckert A, Higgins D. CDC Public Health Imagen Library. Atlanta, Estados Unidos:Centers for Disease Control and Prevention;2020.Disponible en:https://phil.cdc.gov/Details.aspx?pid=23313

  22. Martins Vale AJ, Lopes Fernandes AC, Pierdoná Guzen F, Francisco Irochima Pinheiro F , Pereira de Azevedo E, Ney Cobucci R. Susceptibility to COVID-19 in Pregnancy, Labor, and Postpartum Period: Immune System, Vertical Transmission, and Breastfeeding. Front Glob Womens Health. 2021[citado 09/11/2021];2:602572. Disponible en:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593969/

  23. Mallah SI, Ghorab OK, Al-Salmi S, Abdellatif OS, Tharmaratnam T, Iskandar MA, et al. COVID-19: breaking down a global health crisis. Ann Clin Microbiol Antimicrob. 2021[citado 09/11/2021]; 20(1):35. Disponible en:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129964/pdf/12941_2021_Article_438.pdf

  24. 24.Chilamakuri R, Agarwal S. COVID-19: Characteristics andTherapeutics. Cells. 2021[citado 09/11/2021];10(2):206. Disponible en: https://www.mdpi.com/2073-4409/10/2/206

  25. Chen R, Zhang S, Su S, Ye H, Shu H. Interactions Between Specific Immune Status of Pregnant Women and SARS-CoV-2 Infection. Front Cell Infect Microbiol. 2021[citado 09/11/2021]; 11: 721309. Disponible en:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387674/pdf/fcimb-11-721309.pdf

  26. Wastnedge EAN, Reynolds RM, van Boeckel SR, Stock SJ, Denison FC, et al. Pregnancy and COVID-19. Physiol Rev. 2021[citado 09/11/2021]; 101: 303–318. Disponible en:https://journals.physiology.org/doi/pdf/10.1152/physrev.00024.2020

  27. Córdoba Vives S, Fonseca Peñaranda G. COVID-19 y Embarazo. Rev Med Costa Rica 2020[citado 09/11/2021];86(629):22-29. Disponible en:https://www.medigraphic.com/pdfs/revmedcoscen/rmc-2020/rmc20629f.pdf

  28. Ferrer Oliveras R, Mendoza M, Capote S, Pratcorona L, Esteve Valverde E, Cabero Roura L, et al. Immunological and physiopathological approach of COVID-19 in pregnancy. Arch Gynecol Obstet .2021[citado 09/11/2021];304(1):39-57. Disponible en:https://link.springer.com/article/10.1007/s00404-021-06061-3

  29. Miguel Soca P, Feria Díaz GE, González Benítez SN, Leyva Montero MA.Obesidad, inflamación y embarazo, una tríada peligrosa. Rev Cubana Obstet Ginecol.2021[citado 09/11/2021]; 46 (4) Disponible en:http://revginecobstetricia.sld.cu/index.php/gin/article/view/605

  30. González Villalva A, de la Peña Díaz A, Rojas Lemus M, López Valdez N, Ustarroz Cano M,García Peláez I,et al. Fisiología de la hemostasia y su alteración por la coagulopatía en COVID-19. Rev Fac Med. 2020[citado 09/11/2021];63(5):45-57. Disponible en:https://www.revistafacmed.com/index.php?option=com_phocadownload&view=file&id=1344:fisiologa-de-la-hemostasia-y-su-alteracin&Itemid=1

  31. Lokken EM, Taylor GG, Huebner EM,Jeroen Vanderhoeven,Hendrickson S, Coler B, et al. Higher severe acute respiratory syndrome corona-virus 2 infection rate in pregnant patients. Am J Obstet Gynecol.2021[citado 09/11/2021];225(1):75.e1-75.e16. Disponible en:https://doi.org/10.1016/j.ajog.2021.02.011

  32. Debelenko L, Katsyv I, Chong AM, Peruyero L, Szabolcs M, Uhlemann AC. Trophoblast damage with acute and chronic intervillositis: disruption of the placental barrier by severe acute respiratory syndrome coronavirus 2. Hum Pathol. 2021 [citado 09/11/2021]; 109: 69-79. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733682/pdf/main.pdf

  33. Papageorghiou AT, Deruelle P, Gunier RB, Rauch S, García-May PK, Mhatre M, et al. Preeclampsia and COVID-19: resultsfrom the INTERCOVID prospective longitudinal study. Am J Obstet Gynecol.2021[citado 09/11/2021];225(3):289.e1-289.e17. Disponible en:https://www.sciencedirect.com/science/article/abs/pii/S0002937821005615?via%3Dihub

  34. Conde Agudelo A, Romero R. SARS-CoV-2 infection during pregnancy and risk of preeclampsia: a systematic review and meta-analysis. Am J Obstet Gynecol.2022[citado 09/11/2021]:226(1):68-89.Disponible en:https://www.sciencedirect.com/science/article/abs/pii/S000293782100795X?via%3Dihub

  35. Luxi N, Giovanazzi A, Capuano A, Crisafulli S , Cutroneo PM,Pia Fantini M , et al. COVID-19 Vaccination in Pregnancy, Paediatrics, Immunocompromised Patients, and Persons with History of Allergy or Prior SARS-CoV-2 Infection: Overview of Current Recommendations and Pre- and Post-Marketing Evidence for Vaccine Efficacy and Safety. Drug Saf. 2021[citado 09/11/2021]:44(12):1247-1269.Disponible en:https://link.springer.com/article/10.1007/s40264-021-01131-6

  36. Garg, I, Shekhar R, Sheikh, AB, Pal S. COVID-19 Vaccine in Pregnant and LactatingWomen: A Review of Existing Evidence and Practice Guidelines. Infect Dis Rep.2021[citado 09/11/2021];13(3):685-699. Disponible en: https://doi.org/10.3390/idr13030064

  37. Stafford IA, Parchem JG, Sibai BM. The coronavirus disease 2019 vaccine in pregnancy: risks, benefits, and recommendations. Am J Obstet Gynecol. 2021 [citado 09/11/2021]; 224(5): 484-495. Disponible en:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847190/pdf/main.pdf

  38. Kharbanda EO, Haapala J, DeSilva M, Vazquez Benitez G, Vesco KK, Naleway AL, et al. Spontaneous Abortion Following COVID-19 Vaccination During Pregnancy. JAMA. 2021[citado04/11/2021];326(16):1629-1631. Disponible en:https://jamanetwork.com/journals/jama/fullarticle/2784193




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