2024, Number 09
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Ginecol Obstet Mex 2024; 92 (09)
Risk of pre-eclampsia in adolescent primigravidae
Chicana MJ, Asencio CM, Galdos-Bejar M, Yhuri CN
Language: Spanish
References: 28
Page: 386-395
PDF size: 212.82 Kb.
ABSTRACT
Objective: To associate the risk of preeclampsia among nulliparous adolescents living
in a region of the peruvean jungle.
Materials and Methods: Retrospective cohort study including pregnant nulliparous
adolescents attended at the Hospital II-1 of Rioja, located in the Peruvian
jungle, from January to December 2019. The population was divided into adolescent
(over or under 19 years of age) and adult (over 19 years of age) pregnant women.
Poisson regression with robust variance was used to measure relative risk with 95%
confidence interval.
Results: A total of 357 pregnant women were included: 54.9% adolescents and
45.1% adults. Gestational hypertension was diagnosed in 18.8% and half of them
(9.9%) had pre-eclampsia. An association was found between age and pre-eclampsia
(RR = 1.569; 95%CI: 0.79-3.01), i.e. adolescents had a 56.9% higher risk of preeclampsia.
Obesity increased the risk of pre-eclampsia by 136% (RR: 2.36; 95%CI:
1.03-5.33; p = 0.04).
Conclusions: In adolescents, pregnancy and obesity were risk factors for preeclampsia.
Pregnancy prevention programs and lifestyle interventions like exercise, diet and
behavioural strategies are crucial to avoid this pregnant complication.
REFERENCES
Sánchez-Aguilar A, Hidalgo-Calle N, Benavides H, et al.Perú: Facundidad Adolescente. Síntesis Estadística. InstitutoNacional de Estadística e Informática. https://www.inei.gob.pe/media/MenuRecursivo/publicaciones_digitales/Est/Lib1596/libro.pdf
Carhuavilca-Bonett D, Sánchez-Aguilar A, Hidalgo-CalleN, et al. Perú: Encuesta demográfica y de salud familiarENDES 2020. Instituto Nacional de Estadística e Informática.https://proyectos.inei.gob.pe/endes/2020/INFORME_PRINCIPAL_2020/INFORME_PRINCIPAL_ENDES_2020.pdf
Adolescent pregnancy. World Health Organization.https://www.who.int/en/news-room/fact-sheets/detail/adolescent-pregnancy
Marvin-Dowle K, Kilner K, Burley V, et al. Impact of adolescentage on maternal and neonatal outcomes in the Bornin Bradford cohort. BJM 2018; 8: e016258. https://doi.org/10.1136/bmjopen-2017-016258
Gurung R, Målqvist M, Hong Z, et al. The burden of adolescentmotherhood and health consequences in Nepal.BCM Pregnancy and Childbirth 2020; 20 (318). https://doi.org/10.1186/s12884-020-03013-8
Indarti J, Al Fattah A, Dewi Z, et al. Teenage pregnancy:obstetric and perinatal outcome in a tertiary centre inIndonesia. Obstet Gynecol Int 2020; 2787602. https://doi.org/10.1155/2020/2787602
Pacheco-Romero José. Introducción al simposio sobre preeclampsia.Rev peru ginecol obstet 2017; 63 (2): 199-206.http://www.scielo.org.pe/pdf/rgo/v63n2/a07v63n2.pdf
Burton G, Redman C, Roberts J, et al. Pre-eclampsia:pathophysiology and clinical implications. BMJ 2019; 366(l2381). https://doi.org/10.1136/bmj.l2381
Brosens I, Muter J, Ewington L, et al. Adolescent preeclampsia:pathological drivers and clinical prevention.Reproductive sciences 2019; 26 (2): 159-171. https://doi.org/10.1177/1933719118804412
Kawakita T, Wilson K, Grantz KL, et al. Adverse Maternaland Neonatal Outcomes in Adolescent Pregnancy. J PediatrAdolesc Gynecol 2016; 29 (2): 130-36. https://doi.org/10.1016/j.jpag.2015.08.006
Ganchimeg T, Ota E, Morisaki N, et al. Pregnancy andchildbirth outcomes among adolescent mothers: a WorldHealth Organization multicountry study. BJOG 2014; 121(1): 40-48. https://doi.org/10.1111/1471-0528.12630
Medhi R, Das B, Das A, et al. Adverse obstetrical andperinatal outcome in adolescent mothers associated withfirst birth: a hospital-based case-control study in a tertiarycare hospital in North-East India. Adolesc Health Med Ther2016; 7: 37-42. https://doi.org/10.2147/AHMT.S91853
Pergialiotis V, Vlachos DE, Gkioka E, et al. Teenage pregnancyantenatal and perinatal morbidity: results from atertiary centre in Greece. J Obstet Gynaecol 2015; 35 (6):595-9. https://doi.org/10.3109/01443615.2014.991285
Leppälahti S, Gissler M, Mentula M, et al. Is teenagepregnancy an obstetric risk in a welfare society? Apopulation-based study in Finland, from 2006 to 201.BMJ Open 2013; 3: e003225. https://doi.org/10.1136/bmjopen-2013-003225
ACOG Practice Bulletin No. 202: Gestational Hypertensionand Pre-eclampsia. Obstet Gynecol 2019; 133 (1): e1‐e25.https://doi.org/10.1097/AOG.0000000000003018
Urviola R. Adolescencia como factor de riesgo en complicacionesmaternas y perinatales. Arequipa: UniversidadNacional de San Agustín Arequipa. 2018;37. https://repositorio.unsa.edu.pe/items/981fd273-282a-492e-854f-0c6ac866e5f8
Okumura J, Maticorena D, Tejeda J, et al. Embarazoadolescente como factor de riesgo para complicacionesobstétricas y perinatales en un hospital de Lima, Perú. RevBras Saude Mater Infant 2014; 14 (4): 383-92. https://doi.org/10.1590/S1519-38292014000400008
Masoumi S, Kashanian M, Arab E, et al. A comparisonbetween pregnancy outcome in women in 15 to19 and 20to 35 years age group. Med J Islam Repub Iran 2017; 32(3). https://doi.org/10.14196/mjiri.31.140
Estrada E. Complicaciones obstétricas en primigestasadolescentes comparadas con primigestas adultas atendidasen el Hospital Nacional Hipólito Unanue, de eneroa diciembre del 2017. Lima: Universidad Nacional FedericoVillarreal 2018; 26. https://repositorio.unfv.edu.pe/handle/20.500.13084/1780
Pacheco-Romero J, Villacorta A, Del Carpio L, et al. Repercusiónde la preeclampsia/ eclampsia en la mujerperuana y su perinato, 2000-2006. Rev peru ginecolobstet 2014; 60 (4): 279-90. http://www.scielo.org.pe/scielo.php?pid=S2304-51322014000400003&script=sci_arttext&tlng=pt
Macedo TCC, Montagna E, Trevisan CM, et al. Prevalenceof pre-eclampsia and eclampsia in adolescent pregnancy:A systematic review and meta-analysis of 291,247adolescents worldwide since 1969. Eur J Obstet GynecolReprod Biol 2020; 248: 177-86. https://doi.org/10.1016/j.ejogrb.2020.03.043
Conde-Agudelo A, Belizán JM. Risk factors for pre-eclampsiain a large cohort of Latin American and Caribbean women.BJOG 2000; 107 (1): 75-83. https://www.pregnancycoach.com/docs/CondeAgudeloRiskFactorsForPreeclampsia.pdf
Blanco E, Marin M, Nuñez L, et al. Adverse pregnancyand perinatal outcomes in Latin America and the Caribbean:systematic review and meta-analysis. Rev PanamSalud Publica 2022; 46: e21. https://doi.org/10.26633/RPSP.2022.21
Hung T, Hsieh T. Pregestational body mass index, gestationalweight gain, and risks for adverse pregnancy outcomesamong Taiwanese women: A retrospective cohort study.Taiwanese J Obstet Gynecol 2016; 575-81. http://dx.doi.org/10.1016/j.tjog.2016.06.016
Savitri AI, Zuithoff P, Browne JL, et al. Does pre- pregnancyBMI determine blood pressure during pregnancy? A prospectivecohort study. BMJ Open 2016; 6 (011626). https://doi.org/10.1136/bmjopen-2016-011626
Aliyu MH, Luke S, Kristensen S, et al. Joint effect of obesityand teenage pregnancy on the risk of pre-eclampsia: apopulation-based study. J Adolesc Health 2010; 46 (1):77-82. https://doi.org/10.1016/j.jadohealth.2009.06.006
Abdel Razik M, El-Berry S, Abosereah M, et al. Prophylactictreatment for pre-eclampsia in high-risk teenage primigravidaewith nitric oxide donors: a pilot study. J MaternFetal Neonatal Med 2016; 29 (16): 2617-20. https://doi.org/10.3109/14767058.2015.1094793
Vigil-De Gracia P, Olaya-Garay SX, Mata Hernández C, et al.Blood pressure changes in adolescents with pre-eclampsia:a multicenter, case-control study in Latin American Hospitals.J Obstet Gynaecol Can. 2021;43(1):50-57. https://doi.org/10.1016/j.jogc.2020.06.024