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Archivos de Medicina de Urgencia de México

2024, Number 2

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Arch Med Urg Mex 2024; 16 (2)

Pathophysiology of maternal preeclampsia

Cruz-Martínez FJ

Language: Spanish
References: 50
Page: 109-116
PDF size: 507.49 Kb.


ABSTRACT

Once the first stage of early-onset preeclampsia known as placental preeclampsia occurs, microparticles of the syncytiotrophoblast are injected into the systemic circulation producing the maternal syndrome of preeclampsia which consists of arterial hypertension, proteinuria, capillary leak syndrome and a tendency toward microangiopathic thrombosis. These mechanisms interact with each other to produce organ failure that leads to death if the pregnancy is not interrupted. In the article I will explain the pathophysiology of each of these components, describing mechanisms of imbalance in vascular mechanics, disorders in fluid dynamics, glomeruloendotheliosis and procoagulability.


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