2024, Number 3
<< Back
Otorrinolaringología 2024; 69 (3)
Tracheal mucosa melanoma: A rare diagnosis in an unusual site
Barrón SMA, Barrón CAC, Campos NLA, Pérez CJA
Language: Spanish
References: 18
Page: 218-224
PDF size: 556.67 Kb.
ABSTRACT
Background: Melanoma is a malignant lesion with aggressive behavior, with a
rapid evolutionary process that may cause melanic and amelanic lesions, particularly
in the mucosa.
Clinical case: A 48-year-old male patient initially diagnosed as an asthmatic
process and, given the poor response to treatment, he was sent to Otorhinolaryngology
service, where a tracheal neoformation with a histopathological report of melanoma
was confirmed.
Conclusions: The early identification of melanoma allows to offer the patient
and clinician care choices and damage limitation.
REFERENCES
Chang AE, Karnell LH, Menck HR. The National Cancer Data Base report on cutaneous and noncutaneousmelanoma: a summary of 84,836 cases from the past decade. The American College of Surgeons Commissionon Cancer and the American Cancer Society. Cancer 1998; 83 (8): 1664-78. doi: 10.1002/(sici)1097-0142(19981015)83:8<1664::aid-cncr23>3.0.co;2-g
Guy GP Jr, Thomas CC, Thompson T, Watson M, et al. Centers for Disease Control and Prevention (CDC).Vital signs: melanoma incidence and mortality trends and projections - United States, 1982-2030. MMWRMorb Mortal Wkly Rep 2015; 64 (21): 591-6.
Tomicic J, Wanebo HJ. Mucosal melanomas. Surg Clin North Am 2003; 83 (2): 237-52. doi: 10.1016/S0039-6109(02)00100-7
Spadafora M, Santandrea G, Lai M, et al. Clinical review of mucosal melanoma. The 11 year experience ofa referral center. Dermatol Pract Concept 2023; 13 (1): e2023057. Doi:https://doi.org/10.5826/dpc.1301a57
Papaspyrou G, Garbe C, Schadendorf D, et al. Mucosal melanomas of the head and neck: new aspects ofthe clinical outcome, molecular pathology, and treatment with c-kit inhibitors. Melanoma Res 2011; 21 (6):475-82. doi: 10.1097/CMR.0b013e32834b58cf
Patrick RJ, Fenske NA, Messina JL. Primary mucosal melanoma. J Am Acad Dermatol 2007; 56 (5): 828-34.doi: 10.1016/j.jaad.2006.06.017
Elder DE, Bastian BC, Cree IA, Massi D, et al. World Health Organization 2018 Classification of Cutaneous,Mucosal and Uveal Melanoma: Detailed analysis of 9 distinct subtypes defined by their pathway. ArchPathol Lab Med 2020; 144 (4): 500-522. doi: https://doi.org/10.5858/arpa.2019-0561-RA
Spencer KR, Mehnert JM. Mucosal melanoma: Epidemiology, biology and treatment. Cancer Treat Res 2016;167: 295-320. doi: 10.1007/978-3-319-22539-5_13
Mao L, Qi Z, Zhang L, Guo J, Si L. Immunotherapy in acral and mucosal melanoma: Current status andfuture directions. Front Immunol 2021; 12: 680407. doi: 10.3389/fimmu.2021.680407
Bachar G, Loh KS, O’Sullivan B, Goldstein D, et al. Mucosal melanomas of the head and neck: experienceof the Princess Margaret Hospital. Head Neck 2008; 30 (10): 1325-31. doi: 10.1002/hed.20878
Kempele AA, Azarjana KB, Cema IC, Rivosh AD, et al. Cutaneous and mucosa head and neck melanoma.Melanoma Res 2010; e47-e48. DOI: 10.1097/01.cmr.0000382841.53523.1b
Serman N, Vranic S, Glibo M, Serman L, et al. Genetic risk factors in melanoma etiopathogenesis andthe role of genetic counseling: A concise review. Bosn J Basic Med Sci 2022; 22 (5): 673-682. doi: 10.17305/bjbms.2021.7378
Bobos M. Histopathologic classification and prognostic factors of melanoma: a 2021 update. Ital J DermatolVenerol 2021; 156 (3): 300-321. doi: 10.23736/S2784-8671.21.06958-3
Garbe C, Amaral T, Peris K, Hauschild A, et al; European Dermatology Forum (EDF), the European Associationof Dermato-Oncology (EADO), and the European Organization for Research and Treatment ofCancer (EORTC). European consensus-based interdisciplinary guideline for melanoma. Part 1: Diagnostics- Update 2019.
Mısır AF, Durmuşlar MC, Zerener T, Gün BD. Primary malignant melanoma. Saudi Med J 2016; 37 (4):446-9. doi: 10.15537/smj.2016.4.15017
Gavriel H, McArthur G, Sizeland A, Henderson M. Review: mucosal melanoma of the head and neck. MelanomaRes 2011; 21 (4): 257-66. doi: 10.1097/CMR.0b013e3283470ffd
Jung S, Johnson DB. Management of acral and mucosal melanoma: medical oncology perspective. Oncologist2022; 27 (8): 703-710. doi: 10.1093/oncolo/oyac091
Cabrera R, Recule F. Unusual clinical presentations of malignant melanoma: A review of clinical and histologicfeatures with special emphasis on dermatoscopic findings. Am J Clin Dermatol 2018; Supl 1: 15-23.doi: 10.1007/s40257-018-0373-6