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ISSN 1028-9933 (Electronic)

2022, Number 1

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RIC 2022; 101 (1)

Characterization of patients with severe corneal ulcer and therapeutic keratoplasty

Marrero-Rodríguez E

Language: Spanish
References: 20
Page: 1-12
PDF size: 683.34 Kb.


ABSTRACT

Introduction: Keratoplasty has been the most used technique for the treatment of corneal alterations.
Objective: To describe the clinical-epidemiological characteristics of therapeutic keratoplasty in patients with severe corneal ulcer.
Method: A descriptive and cross-sectional observational study was carried out on 17 eyes of 16 patients operated on for therapeutic keratoplasty who presented severe corneal ulcer, admitted to the Ophthalmology service of the Hospital “Dr. Juan Bruno Zayas Alfonso” in Santiago de Cuba, in the period from January 2018 to December 2019. The variables studied were: age, gender, origin, occupation, predisposing factors, time of evolution prior to admission, previous topical treatment and causal germ. In the statistical analysis, the absolute frequency and the percentage were used for the qualitative variables, and for the quantitative ones, the mean and the standard deviation.
Results: Male patients predominated, retired with more than 60 years. Non-surgical ocular trauma prevailed as a predisposing factor. Prior to admission, antibiotic eye drops were applied more frequently, and the average evolution time was 12.2 days. The most preponderant group of germs was bacteria.
Conclusions: The link between the causal germ and the application of previous topical medications in a prolonged manner favors the torpid evolution of the disease towards severe forms of corneal ulcer. This evolution offers a poor and prolonged response to conventional treatment schemes, which sometimes lead to a therapeutic-tectonic keratoplasty.


REFERENCES

  1. Kanski Jack J. Oftalmología clínica. 9ed. Madrid: Elvesier; 2018.

  2. Frómeta-Ávila M, Díaz-Matos M, Cobas-Díaz L. Úlceras corneales en pacientes atendidos en el Hospital General Docente "Dr. Agostinho Neto", Guantánamo 2014-2019. Rev Inf Cient [Internet]. 2020 [citado 10/01/2022]; 99(1):38-45. Disponible en: http://www.revinfcientifica.sld.cu/index.php/ric/article/view/272

  3. Weisenthal R, Daly M, Freitas D, Feder R. External Disease and Cornea. Am Acad Ophthalmol [Internet]. 2017. [citado 10/01/2022]. Disponible en: https://store.aao.org/media/resources/17937920/BCSC1718_S08fm_nocrops_rgb.pdf

  4. AlMahmoud T, Elhanan M, Elshamsy MH, Alshamsi HN, Fikri M, Abu Z. Manegement of infective corneal ulcers in a high-income developing country. Medicine (Baltimore) [Internet]. 2019 [citado 10/01/2022]; 98(51):e18243. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940151/

  5. Pérez Delgado Z, Relly Noda DO, Miña Oliveros L, García Hernández CD. Tratamiento de la úlcera grave de la córnea con colirio fortificado. Rev Med Electrón [Internet]. 2018 [citado 12/10/2021]; 40(2). Disponible en: http://.medigraphic.com/pdfs/revmedele/me-2018me/182.pdf

  6. Díaz López MD, García Garrote F, Perales Palacios I, Pescador Martín P. Diagnóstico microbiológico de las infecciones oculares. España: Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC); 2019.

  7. López Hernández SM, Matías Díaz Caetillo FM, Gómez Castillo Z, Pérez Parra Z, Fernández García K, Guerra Almaguer M. Rechazo corneal en pacientes operados de queratoplastia penetrante óptica. Rev Cubana Oftalmol [Internet]. 2018 [citada 12/10/2021]; 31(2):1-13. Disponible en: http://scielo.sld.cu/pdf/oft/v31n2/a03_578.pdf

  8. López Hernández SM, Castañeda Rojas JS, Castillo Pérez A, Moreno Ramírez ME, Fernández García K, Guerra Almaguer M. Factores predisponentes a queratoplastia terapéutica en los pacientes con úlcera grave de la córnea. Rev Cubana Oftalmol [Internet]. 2019 [citada 12/10/2021]; 32(2): Disponible en: http://www.revoftalmologia.sld.cu/index.php/oftalmologia/article/view/730/html_390

  9. Castro-Cárdenas K, Espinosa-Gómez A, Cossío-González E. Úlcera corneal grave secundaria a artritis reumatoide. MediCiego [Internet]. 2019 [citada 12/10/2021]; 25(1):89-98. Disponible en: http://www.revmediciego.sld.cu/index.php/mediciego/article/view/658/2296

  10. Popov G, Marrero Faz EA. Ulcera Grave de la Córnea. Bol Hospital V.I. Lenin; 1968 Dic 1 (5-6-2).

  11. López Hernández SM, Rodríguez de Paz U, Hernández Fernández Y. Queratitis infecciosa. En: Ríos Torres M, Fernández Argones L, Hernández Silva JR, Ramos López M. Oftalmología. Diagnóstico y tratamiento. Ciudad de la Habana: Editorial de Ciencias Médicas; 2018.

  12. Ku Lozano J, Samudio M, Penniecook-Sawyers JA, Abente S, Duré C. Características clínico-epidemiológicas y evolución del tratamiento en pacientes con úlceras corneales. Mem Inst Inv Cienc Salud [Internet]. 2019 [citada 10/10/2021]; 17(1):16-24. Disponible en: http://scielo.iics.una.py/pdf/iics/v17n1/1812-9528-iics-17-01-16.pdf

  13. Ramos-Suárez A, Fernández-Barrientos Y. La integridad de la supericie ocular en las úlceras corneales: a propósito de 3 casos. Actual Med Granada. 2018; 103:(804):98-101.

  14. Parra Rodríguez DS, García Carmona KP, Vázquez Maya L, Bonifaz A. Incidencia de úlceras corneales microbianas en el Servicio de Oftalmología del Hospital General de México Dr. Eduardo Liceaga. Rev Mex Oftalmol [Internet]. 2016 [citada 10/10/2021]; 90(5):209-214. Disponible en: https://cyberleninka.org/article/n/659417

  15. Irías Benavides RA. Factores de riesgo asociados a úlceras corneales en pacientes ingresados al Centro Nacional de Oftalmología en el período de enero 2014 a enero del 2015 [Tesis Oftalmólogo]. Managua: Universidad Nacional Autónoma de Nicaragua Unan; 2016 [citado 14/05/2021]. Disponible en: http://repositorio.unan.edu.ni/3009/7/88x31_cc.png

  16. Al-Ghafri A, Al-Raisi A. The epidemiology of nonviral microbial keratitis in a tertiary care center in Muscat, Oman. Oman J Ophthalmol. 2018;11(3):213.

  17. Mokey Castellanos MO, Álvarez Rivero MB, Tian Y. Queratolpastia en perforación corneal. Rev Cubana Oftalmol [Internet]. 2020 [citada 10/10/2021]; 33(1):e838. Disponible en: http://www.revoftalmologia.sld.cu/index.php/oftalmologia/article/view/838/776

  18. Ranjini CY, Waddepally VV. Microbial Profile of Corneal Ulcers in a Tertiary Care Hospital in South India. J Ophthalmic Vis Res [Internet]. 2016 [citado 26/04/2021]; 11(4):363-367. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139547/

  19. Barros Duarte MC, Nardi Becker G, Gubert Muller G, Francisco Tuon F. Infectious keratitis in southern Brazil: a comparison culture negative and culture positive patients. Rev Bras Oftalmol [Internet]. 2020 [citado 12/01/2022]; 79(1):46-52. Disponible en: https://www.scielo.br/j/rbof/a/z6D4CLbT9np6pHqYbQbYvLM/?lang=en

  20. Farias R, Pinho L, Santos R. Epidemiological profile of infectious keratitis. Rev Bras Oftalmol [Internet]. 2017 [citado 12/01/2022]; 76(3):116-20. Disponible en: https://www.scielo.br/j/rbof/a/HZKdHyRCgJxxzMVxJrbbVxw/?format=pdf&lang=en




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