López GPE, Celis AEM, Moraila GBG, Torrontegui ZA, González LR, Gutiérrez CM

Language: Spanish
References: 27
Page: 114-123
PDF size: 318.41 Kb.

ABSTRACT

Background: Brown tumor, also known as giant cell granuloma associated with hyperparathyroidism, is a rare non-neoplastic lesion. It is produced by abnormal bone metabolism, with an increase in osteoclastic activity due to elevated parathyroid hormone levels. It has been observed in 4.5% of cases of primary hyperparathyroidism and in approximately 1.5-1.7% of cases of secondary hyperparathyroidism.
Clinical case: A 26-year-old male patient with a 15-year history of chronic kidney disease on renal replacement therapy with hemodialysis and severe secondary hyperparathyroidism with a progressively growing tumor palpable in the right maxillary region with displacement of a dental piece. Surgical management of the tumor was proposed, and histopathological examination revealed a brown tumor secondary to hyperparathyroidism.
Conclusions: The appropriate diagnosis and management of brown tumors in craniofacial structures require a multidisciplinary approach, with evaluation by specialists in Otorhinolaryngology, Maxillofacial surgery, Nephrology, and Endocrinology.

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