2024, Number 2
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Otorrinolaringología 2024; 69 (2)
Intranasal phototherapy in the treatment of allergic rhinitis
Bohorquez MRI, Romero RLA, Aboultaif SNH, Aparicio CDJ, Carmona MJK
Language: Spanish
References: 15
Page: 91-100
PDF size: 222.46 Kb.
ABSTRACT
Objectives: To determine the effectiveness of intranasal phototherapy in the treatment of allergic rhinitis.
Materials and Methods: Explanatory, prospective, experimental, field and transversal study was done
with patients with allergic rhinitis from 18 to 65 years. They were divided into 2 groups of 15 patients, Group A
received intranasal phototherapy and Group B received topical corticosteroids and antihistamines. The Rhinoconjunctivitis
Quality of Life Questionnaire was applied, and a nasal mucus cytology sample was taken.
Results: There were included 30 patients. According to the ARIA classification, moderate-severe persistent
allergic rhinitis affected to 10, allergic rhinitis to 9, moderate severe intermittent allergic rhinitis to 6 and mild
intermittent allergic rhinitis to 5. In the evaluation of the quality of life of these patients, considerable clinical
improvement was obtained in 23 items in patients of group A vs 19 items of patients of group B, considering the
effect of intranasal phototherapy statistically significant (p ‹ 0.001). Before intranasal phototherapy there was
mild eosinophilia in 8 patients, moderate eosinophilia in 2 and 5 patients had not eosinophilia; after phototherapy
all patients (n = 15) had not eosinophilia.
Conclusions: Phototherapy considerably improves the quality of life of patients with allergic rhinitis, as
much as or equal to conventional medical treatment. It represents a novel and alternative treatment before the
population that refuses to the permanent use of medical treatment.
REFERENCES
Ramírez SJ, Salas DD, Borges L, Bouchard M. Perfil de sensibilización a alérgenos inhalantes y alimentariosen pacientes del Instituto de Inmunología Clínica del Estado Mérida-Venezuela. Avances Biomed 2014; 3(3): 129-35.
Monge MA, Rojas OB, Cárdenas BM, Concha GM. Determinación sérica de IgE y recuento de eosinófilos enmoco nasal de pacientes menores de edad para diagnosticar rinitis alérgica. Polo del conocimiento: revistacientífico-profesional. 2022; 7 (7): 672-694.
Mullol J, Valero A. Actualización del manejo de la rinitis alérgica. Guías GEMA y MACVIA-ARIA. Rev Rinol2019; 19 (1): 7-18.
Bouquet J, Vignola AM, Campbell A, Michel FB. Pathophysiology of allergic rhinitis. Int Arch Allergy Immunol1996; 110 (3): 207-218. doi:10.1159/000237289
Koreck A, Szechenyi A, Morocz M, et al. Effects of intranasal phototherapy on nasal mucosa in patientswith allergic rhinitis. J Photochem Photobiol B 2007; 89 (2-3): 163-169. doi:10.1016/j.jphotobiol.2007.09.013
Juniper EF, Guyatt GH. Development and testing of a new measure of health status for clinical trials inrhinoconjunctivitis. Clin Exp Allergy 1991; 21 (1): 77-83. doi:10.1111/j.1365-2222.1991.tb00807.x
Juniper EF, Guyatt GH, Griffith LE, Ferrie PJ. Interpretation of rhinoconjunctivitis quality of life questionnairedata. J Allergy Clin Immunol 1996; 98 (4): 843-845. doi:10.1016/s0091-6749(96)70135-5
Kafie LC. Citograma nasal: utilidad en la práctica clínica de alergias. Rev Med Hondur 1989; 57 (1): 28-32.
Ittai Neuman, Yehuda Finkelstein. Narrow-band red light phototherapy in perennial allergic rhinitis andnasal polyposis. Ann Allergy Asthma Immunol 1997; 78: 399- 406.
Cingi C, Yaz A, Cakli H, Ozudogru E, et al. The effects of phototherapy on quality of life in allergic rhinitiscases. Eur Arch Otorhinolaryngol 2009; 266: 1903-1908.
Koreck A, Csoma Z, Bodai L, Ignacz F, Szabo A, Kadocsa E, et al. Rhinophototherapy: a new therapeutictool for the management of allergic rhinitis. J Allergy Clin Immunol 2005; 115 (3): 541-547. doi:10.1016/j.jaci.2004.11.005
Albu S, Baschir S. Intranasal phototherapy versus azelastine in the treatment of seasonal allergic rhinitis.Auris Nasus Larynx 2013; 40: 447-451.
Alyasin S, Hesamedin S, Houshmand H, Esmaeilzadeh H, Jelodar S, Amin R. Short time efficiency of rhinophototherapyin management of patients with allergic rhinitis resistant to medical therapy. Iran J AllergyAsthma Immunol 2016; 15 (4): 317-327.
Tatar EÇ, Korkmaz H, Sürenoğlu UA, Saylam G, Ozdek A. Effects of rhinophototherapy on quality of lifein persistant allergic rhinitis. Clin Exp Otorhinolaryngol 2013; 6 (2): 73-77. doi:10.3342/ceo.2013.6.2.73
Yurttas V, Şereflican M, Erkoçoğlu M, Terzi EH, Kükner A, Oral M. Histopathological effects of intranasalphototherapy and nasal corticosteroids in allergic rhinitis in a rabbit model. J Photochem Photobiol B 2015;149: 289-291. doi:10.1016/j.jphotobiol.2015.06.011