2022, Number 1
Antiviral potential in algotherapy
Language: Spanish
References: 20
Page:
PDF size: 248.06 Kb.
ABSTRACT
Oceans have been the most valuable food source on Earth. Almost half of atmospheric oxygen is produced by seaweed. Besides, it is considered a natural and attractive biotechnological source of new antibiotics. The antimicrobial activity of its compounds is a promising basis for designing innovative pharmaceutical products. They can become both a reliable alternative to traditional antimicrobial agents, and an effective synergistic adjunct to antibiotic therapy. This review focuses on algae that have been shown to possess immunomodulatory properties from their bioactive molecules, with a particular interest on antiviral activity and on compiling information related to their influence on the novel coronavirus. The objective is to empower rehabilitators and the scientific community with this contribution of thalassotherapy in the struggle against COVID-19. The review is based on references from the main databases such as MedLine, Enbase, Lilacs, SciELO, Pubmed and Virtual Health Library. The methodology used was the search and selection of the most relevant articles on the subject. Documentation supporting the antiviral potential of algae-derived molecules, and specifically against SARS-CoV-2, is particularly broad. Despite the progress on the field, studies on practical implications, clinical research and demonstration scale are still needed.REFERENCES
Hamidi M, Safarzadeh-Kozani P, Safarzadeh-Kozani P, Pierre G, Michaud P, Delattre C. Marine Bacteria versus Microalgae: Who Is the Best for Biotechnological Production of Bioactive Compounds with Antioxidant Properties and Other Biological Applications? Mar Drugs. 2020 [acceso 02/07/2021];18(1):28. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024282/ DOI:10.3390/md18010028
Besednova NN, Andryukov BG, Zaporozhets TS, Kryzhanovsky SP, Kuznetsova TA, Fedyanina LN, et al. Algae Polyphenolic Compounds and Modern Antibacterial Strategies: Current Achievements and Immediate Prospects. Biomedicines. 2020 [acceso 05/07/2021];8(9)342. Disponible en: https://www.mdpi.com/2227-9059/8/9/342/htm DOI:10.3390/biomedicines8090342
Chen X, Song L, Wang H, Liu S, Yu H, Wang X, et al. Partial Characterization, the Immune Modulation and Anticancer Activities of Sulfated Polysaccharides from Filamentous Microalgae Tribonema sp. Molecules. 2019 [acceso 12/07/2021]; 24(2):322. Disponible en: https://www.mdpi.com/1420-3049/24/2/322/htm,doi:10.3390/molecules 24020322.
Hans N, Malik A, Naik S. Antiviral activity of sulfated polysaccharides from marine algae and its application in combating COVID-19: Mini review. Bioresour Technol Rep. 2021 [acceso 05/07/2021];13:100623. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836841/,doi:10.1016/j.biteb.2020.100623
Kuznetsova TA, Andryukov BG, Makarenkova ID, Zaporozhets TS, Besednova NN, Fedyanina LN, et al. The Potency of Seaweed Sulfated Polysaccharides for the Correction of Hemostasis Disorders in COVID-19. Molecules. 2021 [acceso 12/07/2021];26(9):2618. Disponible en:https://www.mdpi.com/1420-3049/26/9/2618/htm,doi:10.3390/molecules26092618
Talukdar J, Bhadra B, Dattaroy T, Nagle V, Dasgupta S. Potential of natural astaxanthin in alleviating the risk of cytokine storm in COVID-19. Biomed Pharmacother. 2020 [acceso 30/03/2021]; 132:110886. Disponible en: https:// www.ncbi.nlm.nih.gov/pmc/articles/PMC7566765/,doi:10.1016/j.biopha.2020.110886.
Singh S, Sk MS, Sonawane A, Kar P, Sadhukhan Se. Plant-derived natural polyphenols as potential antiviral drugs against SARS-CoV-2 via RNA-dependent RNA polymerase (RdRp) inhibition: an in-silico analysis. J Biomol Struct Dyn. 2021 [acceso 10/05/2021];39(16):6249-64. DOI: 10.1080/07391102.2020.1796810
Díaz-Domínguez G, Marsán Suárez V, del Valle-Pérez L. Principales propiedades inmunomoduladoras y antinflamatorias de la ficobiliproteína C-ficocianina. Rev Cubana Hematología e Inmunología de La Habana. 2016 [acceso 10/05/2021] 32(4). Disponible en: http://www.revhematologia.sld.cu/index.php/hih/article/view/451