2024, Number 3
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Acta Med 2024; 22 (3)
Effectiveness of botulinum toxin type A in the management of chronic anal fissures resistant to conservative therapy in a private practice in Mexico City
Telich TJE, García TIV, Telich VJ, Villanueva SE
Language: Spanish
References: 26
Page: 190-193
PDF size: 160.87 Kb.
ABSTRACT
Introduction: chronic anal fissure is a linear split of the anoderm. Although surgery is the gold standard treatment, its side effects raise concerns. Recent studies have suggested encouraging results for the role of botulinum toxin in the treatment of anal fissures. This study aims to demonstrate the effectiveness of botulinum toxin type A for the treatment of anal fissures.
Material and methods: fifteen patients with a diagnosis of anal fissures refractory to conservative management were included. 16 IU of toxin was applied to each patient and distributed in two sites on the 3 and 9 o'clock axes. They were subsequently evaluated in the outpatient clinic over two months.
Results: 15 patients were treated, seven men (46%) and eight women (53%), with a median age of 39 years (range 22 to 72). Twelve patients (80%) presented a complete resolution of the condition. The rest of the patients underwent surgical procedures due to treatment failure.
Conclusions: BT injection has been an accepted method for the management of CAF. This study demonstrates a cure rate of 80% with a 16 IU dose of botulinum toxin distributed along the 3 and 9 o'clock axes in the anal canal.
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