Alfaro-Orozco LP, Rodríguez-Gutiérrez JS, Caballero-Montes HD, Moran-Portela DJ, Escalante-López LY, López-Moreno IN

Language: Spanish
References: 17
Page: 417-422
PDF size: 542.06 Kb.

ABSTRACT

Multiple myeloma (MM) is a clonal and disorganized hyperplasia of plasma cells in the bone marrow and is accompanied by abnormal monoclonal immunoglobulin production, named M proteins. We report the case of a female patient in her sixth decade of life with a diagnosis of plasmacytic plasmablastic multiple myeloma diagnosed by biopsy of a lytic and tumor lesion in the lumbar spine, which develops skin lesions consisting of multiple erythematous nodules that converge to form plaques adhered to deep planes. A histo-pathological study of the lesions was performed, showing immunoblastic and plasmablastic differentiation with nuclear positivity for MUM1 and cytoplasmic membrane staining of CD138 in neoplastic cells, confirming the diagnosis of cutaneous metastasis secondary to multiple myeloma.

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