Bocanegra-Hernández GT, Cardona-Chavarría JM, Tello-Orduña ER

Language: Spanish
References: 14
Page: 128-133
PDF size: 223.89 Kb.

ABSTRACT

Introduction: with the increase in life expectancy, an increase in complications associated with chronic diseases in older adults is expected. Cognitive impairment is a condition which has shown an association with diabetes mellitus, although its causality is unknown, which is why it is necessary to collect more data from sociodemographic diversity. Objective: identify alterations in cognitive status in older adults and their association with diabetes mellitus. Material and methods: observational, descriptive cross-sectional study, a sample of 378 patients from a universe of 22,801 patients over 60 years of age was considered. History was collected and the Folstein mini-mental test was applied. Results: of the total number of patients identified with altered cognitive status (63), 71% (45) have a history of being diabetic. A significant association was shown (χ² [1, N = 378] = 7.85, p < 0.05). The probability of cognitive alterations is double in older adults with diabetes according to the prevalence ratio. Conclusions: the research demonstrates an association between the presence of diabetes with alterations in cognitive status. The results coincide with those carried out in other regions. The practice of performing the mini-mental test should be considered as part of the approach to diabetic patients.

REFERENCES

1. Sun H, Saeedi P, Karuranga S, Pinkepank M, Ogurtsova K, Duncan BB, et al. IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Res Clin Pract. 2022;183:109119.

2. Khan MAB, Hashim MJ, King JK, Govender RD, Mustafa H, Al Kaabi J. Epidemiology of type 2 diabetes - global burden of disease and forecasted trends. J Epidemiol Glob Health. 2020;10(1):107-111.

3. Sequeira Rojas LA. Deterioro cognitivo moderado y factores de riesgo. Revista Clínica Escuela de Medicina UCR-HSJD. 2019;9(5):16-22.

4. González Martínez P, Oltra Cucarella J, Sitges Maciá E, Bonete López B. Revisión y actualización de los criterios de deterioro cognitivo objetivo y su implicación en el deterioro cognitivo leve y la demencia. Revista de Neurología. 2021;72(8):288-295.

5. Mone P, Gambardella J, Pansini A, de Donato A, Martinelli G, Boccalone E, et al. Cognitive impairment in frail hypertensive elderly patients: role of hyperglycemia. Cells. 2021;10(8):2115.

6. Damanik J, Yunir E. Type 2 diabetes mellitus and cognitive impairment. Acta Med Indones. 2021;53(2):213-220.

7. Samaras K, Makkar S, Crawford JD, Kochan NA, Wen W, Draper B, et al. Metformin use is associated with slowed cognitive decline and reduced incident dementia in older adults with type 2 diabetes: the sydney memory and ageing study. Diabetes Care. 2020;43(11):2691-2701.

8. Sluiman AJ, McLachlan S, Forster RB, Strachan MWJ, Deary IJ, Price JF. Higher baseline inflammatory marker levels predict greater cognitive decline in older people with type 2 diabetes: year 10 follow-up of the Edinburgh Type 2 Diabetes Study. Diabetologia. 2022;65(3):467-476.

9. González HM, Tarraf W, González KA, Fornage M, Zeng D, Gallo LC, et al. Diabetes, cognitive decline, and mild cognitive impairment among diverse hispanics/latinos: study of latinos-investigation of neurocognitive aging results (HCHS/SOL). Diabetes Care. 2020;43(5):1111-1117.

10. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12(3):189-98.

11. Reyes-Beaman S, Beaman P, Garcia-Peña C, Villa RMA, Heres J, Córdova A, et al. Validation of a modified version of the mini-mental state examination (MMSE) in Spanish. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2004;11(1):1-11. doi: 10.1076/anec.11.1.1.29366.

12. Bozanic A, Petermann-Rocha F, Waddell H, Parra-Soto S, Cuevas C, Richardson C, et al. Number of years with type 2 diabetes is associated with cognitive impairment in Chilean older adults: a cross-sectional study. Rev Esp Nutr Hum Diet. 2021;25(3):316-325.

13. Zapata-Tragodara D, Roque H, Runzer-Colmenares FM, Parodi JF. Relación entre trastornos neurocognitivos, Diabetes Mellitus Tipo 2 y otros factores en adultos mayores del Centro Médico Naval del Perú, entre los años 2010 a 2015. Rev Neuropsiquiatr. 2020;83(2):87-96.

14. Fonte Sevillano T, Santos Hedman DJ. Deterioro cognitivo leve en personas mayores de 85 años. Rev Cubana Med. 2020;59(1):e1314.