Duque EL, Martínez-Sánchez LM, Aránzazu CAD, Trujillo HMR, Saavedra VME, Flórez CLM

Language: Spanish
References: 17
Page: 13-16
PDF size: 166.50 Kb.

ABSTRACT

Background. Herpes constitutes a large family of double-stranded deoxyribonucleic acid viruses. Serotypes 6a and 6b are part of the subfamily that cause infections during the first years of life, between six months and two years of age, due to the decrease in maternal antibodies, they also have a greater tropism for the central nervous system and they are responsible for the neurological compromise in most cases.
Materials and methods. A retrospective descriptive study was carried out with patients under 18 years of age diagnosed with herpes virus infection. A non-probabilistic sampling of consecutive cases was carried out.
Results. 56 patients infected by herpes virus were included. The most frequent age was six years, with a predominance of the male sex with 53.6%. The main cause of immunosuppression was cancer, the most frequent being acute lymphoblastic leukemia with 14%. The predominant clinical presentation at the time of diagnosis was fever without focus with 21.4%. The diagnosis was clinical in 46.4% and the main treatment was acyclovir in 46.4%.
Conclusions. The herpes virus mainly affects immunosuppressed male pediatric patients as in acute lymphoblastic leukemia. The diagnosis is mainly clinical in this pathology, without the use of paraclinical tests for confirmation, which makes it difficult to identify the subtype of virus that causes the disease, therefore it is important to emphasize the implementation of accurate diagnostic methods that allow improving the diagnosis, management and quality of life of patients

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