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Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría

2023, Number 1-3

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Alerg Asma Inmunol Pediatr 2023; 32 (1-3)

Association of allergic rhinitis, mites and obstructive sleep apnea-hypopnea syndrome in children. Cases and controls study

Rodríguez SO, Toribio PEC, García-Asensi A

Language: Spanish
References: 22
Page: 5-9
PDF size: 177.64 Kb.


ABSTRACT

Introduction: the association of allergic rhinitis (AR), mites and obstructive sleep apnea-hypopnea syndrome (OSAHS) is a health problem that can occur at different ages. In AR and OSAHS, Dermatophagoides pteronyssinus (Dp), Dermatophagoides siboney (Ds) and Blomia tropicalis (Bt) are mainly involved. Objective: to identify patients with rhinitis who are sensitized to mites and which have been diagnosed with OSAHS. Material and methods: 120 individuals were selected from the allergy registry of the Previsora Polyclinic, Camagüey, Cuba, with a presumptive diagnosis of AR and ages between five and 15 years. All had performed the Prick test with Dp, Ds and Bt; some also, cardio-respiratory polygraphy (PCR) with the ApneaLink AirTM device (ResMed Corp., RFA), using the device's automatic event marking. The sample consisted of 40 cases (those with oral breathing and snoring) and 80 controls (without oral breathing or snoring). The EPIDAT 3.1 program was used to study possible outcomes in cases and controls, using the χ2 test for association and p < 0.05. Also simple diagnostic tests and basic statistical indicators. These values were estimated according to the apnea-hypopnea index (AHI) obtained by PCR. Results: the mean size of the wheal was 6.7 mm in the cases and 4.8 mm in the controls (p = 0.31). The AHI was positive in 55 patients (45.8%); of them, 34 cases (28.3%) and 21 controls (17.5%). The sensitivity and specificity of the PCR showed values that allow confirming the degree of efficacy of the test to diagnose OSAHS. The patients with OSAHS in the cases and controls present an increase in number, with a predominance for cases (p = 0.002). Conclusions: PCR with the ApneaLink device allows the diagnosis of OSAHS in RA.


REFERENCES

  1. Zheng M, Wang X, Zhang L. Association between allergic and nonallergic rhinitis and obstructive sleep apnea. Curr Opin Allergy Clin Immunol. 2018; 18 (1): 16-25.

  2. Cao Y, Wu S, Zhang L, Yang Y, Cao S, Li Q. Association of allergic rhinitis with obstructive sleep apnea: A meta-analysis. Medicine (Baltimore). 2018; 97 (51): e13783. doi: 10.1097/MD.0000000000013783.

  3. Zheng M, Wang X, Ge S, Gu Y, Ding X, Zhang Y et al. Allergic and non-allergic rhinitis are common in obstructive sleep apnea but not associated with disease severity. J Clin Sleep Med. 2017; 13 (8): 959-966.

  4. Rodríguez-Santos O, Reyes-Almaguer M. Eficacia y seguridad de la inmunoterapia sublingual en niños de 6 a 24 meses de edad con rinitis y asma bronquial sensibilizados a los ácaros domésticos. VacciMonitor. 2015; 24 (2): 86-92.

  5. Rodríguez SO, del Valle MN. Inmunoterapia con extractos industriales de ácaros domésticos en niños menores de 5 años de edad con rinitis y asma. VacciMonitor. 2018; 27 (2): 61-66.

  6. Rodríguez-Santos O, García-Asensi A, Ponce-Álvarez C, Galeana-Ríos R, Jardines-Arciniega G, del Valle-Monteagudo N. Importancia de los alérgenos de ácaros domésticos en el diagnóstico de la rinitis alérgica con síndrome de apnea-hipopnea del sueño. VacciMonitor. 2019; 28 (3): 97-102.

  7. Rodríguez-Santos O, García-Asensi A, del Valle-Monteagudo N, Galeana-Río R, Flores-Silverio Z. Inmunoterapia con alérgenos de ácaros en pacientes con rinitis alérgica y apnea obstructiva del sueño. VacciMonitor. 2020; 29 (3): 103-108.

  8. American Academy of Sleep Medicine. International Classification of Sleep Disorder: diagnostic and coding manual. 2nd ed. Westchester (NY): American Academy of Sleep Medicine; 2005.

  9. Olivi RH. Apnea del sueño: cuadro clínico y estudio diagnóstico. Rev Med Clin Condes. 2013; 24 (3): 359-373.

  10. D'Elia C, Gozal D, Bruni O, Goudouris E, Meira E Cruz M. Allergic rhinitis and sleep disorders in children - coexistence and reciprocal interactions. J Pediatr (Rio J). 2021: S0021-7557(21)00176-5. doi: 10.1016/j.jped.2021.11.010.

  11. Durán J, Esnaola S, Ramón R, Iztueta A. Obstructive sleep apnea-hypopnea and related clinical features in a popilation-based sample of subjects aged 30 to 70 years. Am J Respir Crit Care Med. 2001; 163: 685-689.

  12. ResMed. ApneaLinkTM Air application software version 10.2 [CD-ROM]. Martinsried, Munich: ResMed; 2015.

  13. Seiler A, Camilo M, Korostovtseva L, Haynes AG, Brill AK, Horvath T et al. Prevalence of sleep-disordered breathing after stroke and TIA: a meta-analysis. Neurology. 2019; 92 (7): e648-e654. doi: 10.1212/WNL.0000000000006904.

  14. Beaglehole R, Bonita R, Kjellstrom T. Epidemiologia básica. Tord Kjellstrom. Washington D.C.: OPS; 1996. pp. 98-100.

  15. Combs D, Shetty S, Parthasarathy S. Advances in positive airway pressure treatment modalities for hypoventilation syndrome. Sleep Med Clin. 2014; 9: 315-325. Available in: http://dx.doi.org/10.1016/j.jsmc.2014.06.002

  16. Shintaro C, Parque CS. Establishment of a nasal patent passage in the obstructive apnea. Sleep Med Clin. 2019; 14 (1): 41-50.

  17. Magliulo G, Iannella G, Ciofalo A, Polimeni A, De Vincentiis M, Pasquariello B et al. Nasal pathologies in patients with obstructive sleep apnoea. Acta Otorhinolaryngol Ital. 2019; 39 (4): 250-256. doi: 10.14639/0392-100X-2173.

  18. Gadi G, Wali S, Koshak E, Albar M, Fida A, Abdelaziz M et al. The prevalence of allergic rhinitis and atopic markers in obstructive sleep apnea. J Epidemiol Glob Health. 2017; 7 (1): 37-44.

  19. Lloberes P, Durán-Cantolla J, Martínez-García MA, Marín JM, Ferrer A, Corral J et al. Diagnóstico y tratamiento del síndrome de apneas-hipopneas del sueño. Arch Bronconeumol. 2011; 47 (3): 143-156.

  20. Parejo-Gallardo K, Saltos-Cristiano CM. Tratamiento. médico del síndrome de apnea-hipopnea obstructiva del sueño. (SAHOS). Rev Fac Med. 2017; 65: S101-S103. Disponible en: http://dx.doi.org/10.15446/revfacmed.v65n1Sup.59727

  21. Kimoff RJ. Upperairway myopathy is important in the pathophysiology of obstructive sleep apnea. J Clin Sleep Med. 2007; 3 (6): 567-569.

  22. Eckert DJ, Saboisky JP, Jordan AS, Malhotra A. Upper airway myopathy is not important in the pathophysiology of obstructive sleep apnea. J Clin Sleep Med. 2007; 3 (6): 570-573.




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