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2023, Number 4

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Dermatología Cosmética, Médica y Quirúrgica 2023; 21 (4)

Cutaneous nodular elastosis with cysts and comedones or Favre-Racouchot syndrome

Sierra-Maeda KY, Segundo-López LD, Arenas R

Language: Spanish
References: 53
Page: 323-330
PDF size: 252.07 Kb.


ABSTRACT

Favre-Racouchot disease is a common disorder characterized by solar elastosis with large, open cysts and comedones, as well as signs of face photoaging, mainly temporal and periorbital, of elderly light-complexioned men. The exact etiopathogenesis of the disease is unknown, but it is known to be a benign condition caused by chronic excessive exposure to ultraviolet light, smoking, and ionizing radiation. The association with skin malignancies is infrequent, suggesting a protective role of some element of the disease against carcinogenesis. Classic histopathological changes reveal an atrophic epidermis and large masses of keratinous material, causing follicular plugging, as well as solar elastotic changes and possible basophilic degeneration of connective tissue. The epidemiological characteristics, pathogenesis, clinical manifestations, diagnostic methods, the association with other entities, differential diagnoses and, treatment options are reviewed.


REFERENCES

  1. Del Río Ysla MB e Iglesias BL, Respuesta quirúrgica del síndromede Favre-Racouchot, MediCiego 2019; 25(3):332-41.

  2. Izumi AK, Marples RR y Kligman AM, Senile (solar) comedones,J Invest Dermatol 1973; 61(1):46-50. doi: 10.1111/1523-1747.ep12674145. pmid: 4268867.

  3. Patterson WM, Fox MD y Schwartz RA, Favre-Racouchot disease,Int J Dermatol 2004; 43(3):167-9. doi: 10.1111/j.1365-4632.2004.01546.x. pmid: 15009383.

  4. Schäfer T, Merkl J, Klemm E, Wichmann HE y Ring J, The epidemiologyof nevi and signs of skin aging in the adult generalpopulation: results of the kora-survey 2000, J Invest Dermatol2006; 126:1490-6.

  5. Agius, JR, Grouped periorbital comedones, Br J Dermatol 1964;76: 158-64.

  6. Friedman SJ y Su WP, Favre-Racouchot syndrome associatedwith radiation therapy, Cutis 1983; 31:306-10.

  7. Lewis KG, Bercovitch L, Dill SW y Robinson-Bostom L, Acquireddisorders of elastic tissue. Part i. Increased elastic tissue andsolar elastotic syndromes, J Am Acad Dermatol 2004; 51:1-21.

  8. Mavilia L, Campolmi P, Santoro G y Lotti T, Combined treatmentof Favre-Racouchot syndrome with a superpulsed carbon dioxidelaser: report of 50 cases, Dermatol Ther 2010; 23 Suppl1:S4-6. doi: 10.1111/j.1529-8019.2009.01279.x. pmid: 20136920.

  9. Vogel S, Mühlstädt M, Molin S, Ruzicka T, Schneider J y HerzingerT, Unilateral Favre-Racouchot disease: evidence for theetiological role of chronic solar damage, Dermatology 2013;226(1):32-4. doi: 10.1159/000346576. Epub: 26 de febrero de2013. pmid: 23446228.

  10. Sonthalia S, Arora R, Chhabra N y Khopkar U, Favre-Racouchotsyndrome, Indian Dermatol Online J 2014; 5(Suppl 2):S128-9. doi: 10.4103/2229-5178.146192. pmid: 25593804; pmcid:pmc4290177.

  11. Kakhandaki AA, Raveendra L, Venkataramana PA y Khandre JS,Favre-Racouchot syndrome with bilateral mechanical ptosis:an unusual presentation, J Cutan Aesthet Surg 2014; 7(2):135-6. doi: 10.4103/0974-2077.138366. pmid: 25136220; pmcid:pmc4134649.

  12. Nyika DT y Ngwanya RM, Actinic comedonal plaque in skinof color: a case report. Clin Case Rep 2018; 6(11):2211-2. doi:10.1002/ccr3.1768. pmid: 30455923; pmcid: pmc6230647.

  13. Paganelli A, Mandel VD, Kaleci S, Pellacani G y Rossi E, Favre-Racouchot disease: systematic review and possible therapeuticstrategies, J Eur Acad Dermatol Venereol; 33(1):32-41. doi:10.1111/jdv.15184. Epub: 7 de agosto de 2018. pmid: 30022555.

  14. Sutherland AE y Green PJ, Favre-Racouchot syndrome in a39-year old female following radiation therapy, J Cutan MedSurg 2014; 18(1):72-4. doi: 10.2310/7750.2013.13011. pmid:24377480.

  15. Jansen T y Plewig G, Favre-Racouchot disease. En DJ Demis(ed.) Clinical dermatology, Filadelfia, Lippincott-Raven, 1997, pp.4-44.

  16. Kulkarni V, Favre-Racouchot syndrome, Indian J Dermatol VenereolLeprol 1991; 57:244-5.

  17. Krajewski PK, Chlebicka I, Stefaniak AA y Szepietowski JC,Coexistence of Favre-Racouchot disease, cutis rhomboidalisnuchae and skin neoplasms, Postepy Dermatol Alergol 2021;38(5):906-8. doi: 10.5114/ada.2020.95605. Epub: 26 de mayo de2020. pmid: 34849143; pmcid: pmc8610054.

  18. Leeuwis-Fedorovich NE, Starink M y Van der Wal AC, Multifocalsquamous cell carcinoma arising in a Favre-Racouchot lesion:report of two cases and review of the literature, J DermatolCase Rep 2015; 9(4):103-6. doi: 10.3315/jdcr.2015.1215. pmid:26848318; pmcid: pmc4733353.

  19. Hedelund L y Wulf HC, Favre-Racouchot disease provoked byuv-a1 and uv-b exposure, Arch Dermatol 2004;140:129-31.

  20. Keough GC, Laws RA y Elston DM, Favre-Racouchot syndrome:a case for smokers’ comedones, Arch Dermatol 1997; 133:796-7.

  21. Breit S, Flaig MJ, Wolff H y Plewig G, Favre-Racouchot-like diseaseafter radiation therapy, J Am Acad Dermatol 2003; 49:117-9.

  22. Hoff NP, Reifenberger J y Bolke E, Radiation-induced Favre-Racouchotdisease, Hautarzt 2012.

  23. Hubiche T y Sibaud V, Localized acne induced by radiation therapy,Dermatol Online J 2014; 20(2).

  24. Yeh C y Schwartz RA, Favre-Racouchot disease: protective effectof solar elastosis, Arch Dermatol Res 2021. doi: 10.1007/s00403-021-02202-5. Epub disponible. pmid: 33651174.

  25. Zhang R y Zhu W, Favre-Racouchot syndrome associated witheyelid papilloma: a case report, J Biomed Res 2012; 26:474-7.

  26. Sawicki J y Barankin B, Dermacase. Can you identify this condition?Favre-Racouchot syndrome, Can Fam Physician 2010;56:247-8.

  27. García-Sepúlveda RD y Mesa-Garza IG, Occupational Favre-Racouchot syndrome, J Gen Fam Med. 2017; 18(6):454-5. doi:10.1002/jgf2.101. pmid: 29264088; pmcid: pmc5729313.

  28. Korting GW, Die Haut im Alter und ihre Krankheiten, Stuttgart,Schattauer, 1973.

  29. Mavilia L, Rossi R, Cannarozzo G, Massi D, Cappugi P y CampolmiP, Unilateral nodular elastosis with cysts and comedones(Favre-Racouchot syndrome): report of two cases treated witha new combined therapeutic approach, Dermatology 2002;204:251.

  30. Moulin G, Thomas L, Vigneau M y Fiere A, A case of unilateralelastosis with cysts and comedones. Favre Racouchot syndrome,Ann Dermatol Venereol 1994; 121:721-3.

  31. Stefanidou M, Ioannidou D y Tosca A, Unilateral nodular elastosiswith cysts and comedones (Favre-Racouchot syndrome),Dermatology 2001; 202:270-1.

  32. Hassounah A y Piérard GE, Kerosis and comedos without prominentelastosis in Favre-Racouchot disease, Am J Dermatopathol,1987; 9(1):15-7. Disponible en: http://dx.doi.org/10.1097/00000372-198702000-00004.

  33. Just M, Ribera M, Monsó E, Lorenzo JC y Ferrándiz C, Effect ofsmoking on skin elastic fibres: morphometric and immunohistochemicalanalysis, Br J Dermatol 2007; 156(1):85-91. Disponibleen: http://dx.doi.org/10.1111/j.1365-2133.2006.07575.x.

  34. Chessa MA, Filippi F, Ferrara F, Patrizi A y Baraldi C, A case ofunilateral inflamed plaques with comedones of the face, DermatolPract Concept 2018; 8(4):292-4. Disponible en: http://dx.doi.org/10.5826/dpc.0804a07.

  35. Sobjanek M, Sławin´ska M y Biernat W, A case of unilateralinflamed plaques with comedones on the face: another caseof an uncommon clinical presentation of Favre-Racouchot disease,Dermatol Pract Concept 2019; 9(4):308-9. Disponible en:http://dx.doi.org/10.5826/dpc.0904a15.

  36. Liu W, Ma J-Y y Ma D-L, Hyperpigmented plaque on a farmer’snose: a quiz, Acta Derm Venereol 2019; 99(10):937-8. Disponibleen: http://dx.doi.org/10.2340/00015555-3236.

  37. Eastern JS y Martin S, Actinic comedonal plaque, J AmAcad Dermatol 1980; 3(6):633-6. Disponible en: http://dx.doi.org/10.1016/s0190-9622(80)80080-6.

  38. Benlier E, Alicioglu B, Kandulu H, Yurdakul ES y Top H, An unusualassociation of cutaneous myxoma with Favre-Racouchotsyndrome, Prague Med Rep 2008; 109(4):321-4.

  39. Platsidaki E, Markantoni V, Balamoti E, Kouris A, RigopoulosD y Kontochristopoulos G, Combination of 30% salicylic acidpeels and mechanical comedone extraction for the treatment ofFavre-Racouchot syndrome, Acta Dermatovenerol Croat 2019;27(1):42-3.

  40. Zheng L-Q, Han X-C, Huang Y, Li H-W y Niu X-D, Favre-Racouchotsyndrome concurrent with chronic granulomatous reaction,J Dermatol 2014; 41(7):642-4. Disponible en: http://dx.doi.org/10.1111/1346-8138.12467.

  41. Cardoso F, Nakandakari S, Zattar GA y Soares CT, Actinic comedonalplaque-variant of Favre-Racouchot syndrome: report oftwo cases, An Bras Dermatol 2015; 90(3 Suppl 1):185-7.

  42. Willemze R, Cerroni L, Kempf W et al., The 2018 update of thewho-eortc classification for primary cutaneous lymphomas,Blood 2019; 134(13):1112.

  43. Mitteldorf C, Stadler R, Sander CA y Kempf W, Folliculotropicmycosis fungoides, J Dtsch Dermatol Ges 2018; 16(5):543-57.

  44. Gu AK, Shi J y Zhang Y, Folliculotropic mycosis fungoides,jama Dermatol 2022; 158(3):316. doi: 10.1001/jamadermatol.2021.5181. pmid: 35107567.

  45. Mohs FE, McCall MW y Greenway HT, Curettage for removal ofthe comedones and cysts of the Favre–Racouchot syndrome,Arch Dermatol 1982; 118:365-6.

  46. Kaya TI, Tursen U, Yazici AC e Ikizoglu G, A simple open comedoneextraction technique for Favre-Racouchot disease, PhotodermatolPhotoimmunol Photomed 2005; 21(5):275-7. doi:10.1111/j.1600-0781.2005.00165.x. pmid: 16149943.

  47. English DT, Martin GC y Reisner JE, Dermabrasion for nodularcutaneous elastosis with cysts and comedones. Favre-Racouchot syndrome, Arch Dermatol 1971; 104(1):92-3. pmid:4256263.

  48. Rai S, Madan V, August PJ y Ferguson JE, Favre-Racouchot syndrome:a novel two-step treatment approach using the carbondioxide laser, Br J Dermatol 2014; 170(3):657-60. doi: 10.1111/bjd.12742. pmid: 24252129.

  49. Davis EC y Callender VD, Aesthetic dermatology for aging ethnicskin, Dermatol Surg 2011; 37(7):901-17. Disponible en: http://dx.doi.org/10.1111/j.1524-4725.2011.02007.x.

  50. Sotiris TG, Nittari G, Sagaro GG y Amenta F, A descriptive studyon the applications of plasma exeresis in dermatology, J ClinAesthet Dermatol 2021; 14(3): E58-62. Epub: 1 de marzo de2021. pmid: 33841619; pmcid: pmc8021407.

  51. Paganelli A, Mandel VD, Pellacani G y Rossi E, Synergic effectof plasma exeresis and non-cross-linked low and high molecularweight hyaluronic acid to improve neck skin laxities, J CosmetDermatol 2020; 19(1):55-60. Disponible en: http://dx.doi.org/10.1111/jocd.12976.

  52. Del Río Ysla MB e Iglesias BL, Respuesta quirúrgica del síndromede Favre-Racouchot, MediCiego 2019; 25(3):332-41.

  53. Merino JE, Gómez MA, Valdez RJ, Morel CM y Orozco LP,Enfermedad de Favre-Racouchot severa. Reporte de un caso,dcmq 2011; 8(3):192-5.




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