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2020, Number 4

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Rev Nefrol Dial Traspl 2020; 40 (4)

Inmunoglobulin G4-Related Kidney Disease

Sánchez-Oro R, Alonso-Muñoz EM

Language: Spanish
References: 40
Page: 314-348
PDF size: 413.54 Kb.


ABSTRACT

Immunoglobulin G4-related disease (IgG4-RD) is an immunomediated fibroinflammatory process. In the last few decades, this disease has been recognized as a systemic disorder encompassing individual involvement of organs, previously unrelated and known as independent entities. Renal involvement in IgG4- RD may be both synchronous and metachronous to other organ compromise, such as that seen in autoimmune pancreatitis, sclerosing cholangitis, retroperitoneal fibrosis, or IgG4-related lymphadenopathy. In this review we present the most frequent manifestations of renal involvement due to IgG4-RD, highlighting the role of imaging tests. The treatment of both IgG4- RD in general and renal involvement in particular are glucocorticoids. It is important to know about this disease, be suspicious about it and make an early and accurate diagnosis.


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