2023, Number 2
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Rev Hematol Mex 2023; 24 (2)
Otorhinolaryngological manifestations of a rare hematological disease: Blastic plasmacytoid dendritic cell neoplasm
Méndez SLM, Montemayor PN, Ramírez MAL, Hernández MA, Mancilla MFJ, Serrano SL
Language: Spanish
References: 6
Page: 101-105
PDF size: 279.07 Kb.
ABSTRACT
Background: Plasmacytoid blast neoplasm is rare, predominates in men. Clinically,
skin lesions are manifested, with no report of compromised airway mucosa.
Clinical case: This paper reports two documented clinical cases with affection
of airway mucosa, CD123 positive, in which the diagnosis of blastic plasmacytoid
dendritic cell neoplasia was confirmed.
Conclusions: Blastic plasmacytoid dendritic cell neoplasia is an underdiagnosed
disease because the clinical presentation can be confused with other hematological or
dermatological diseases. In patients with lesions in the airway mucosa, it is necessary
to consider this hematological disease.
REFERENCES
Avilés-Salas A, Candelaria M, Ponce M, Cañavera-ConstantinoA, Burgos S. Neoplasia blástica de células dendríticasplasmocitoides. Casos clínicos. Revista Médica Chile 2017;145 (9): 1208-1212. http://dx.doi.org/10.4067/s0034-98872017000901208.
Vilcahuamán V, Quinto N, Pacheco M, Paredes A, MoisesC, Sánchez G, Carbajal T. Neoplasia blástica plasmocitoidede células dendríticas. Folia Dermatol Peru 2010; 21 (3):151-156.
Bekkenk MW, Jansen PM, Meijer CJ, Willemze R. CD56+hematological neoplasms presenting in the skin: a retrospectiveanalysis of 23 new cases and 130 cases from theliterature. Ann Oncol 2004; 15 (7): 1097-1108. https://doi.org/10.1093/annonc/mdh268.
Tapia OE, Kam SC, Rifo PL, Villaseca MH. Blastic plasmocytoiddendritic cell neoplasm: Report of one case. RevistaMedica Chile 2012; 140 (10): 1321-1324. DOI: 10.4067/s0034-98872012001000013.
Petrella T, Wechsler J, Courville P, de Muret A, Bosq J,Déchelotte P, et al. Les hématodermies CD4/CD56. AnnPathologie 2014; 24 (3): 241-255. https://doi.org/10.1016/S0242-6498(04)93959-4.
Jacob MC, Chaperot L, Mossuz P, Feuillard J, Valensi F, LerouxD, et al. CD4+ CD56+ lineage negative malignancies: anew entity developed from malignant early plasmacytoiddendritic cells. Haematologica 2003; 88 (8): 941-955.
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