2023, Number Esp
<< Back
Rev Med UAS 2023; 13 (Esp)
Oral mucositis treatments in pediatric patients with chemotherapy. Literature review
Alfonzo-Márquez JA, Argüelles-Marquez V, Sosa-Pacheco KO, Franco-Trejo CS, Luengo-Fereira JA
Language: Spanish
References: 40
Page: 74-87
PDF size: 422.44 Kb.
ABSTRACT
Oral mucositis is a reaction of the mucosa gastrointestinal tract, mainly the oral mucosa, a secondary effect of (chemo-therapy/radiotherapy) oncological treatments. Characterized by erythematous areas and ulcerative lesions causing pain and physical limitation. The objective was to describe the mains treatments for oral mucositis in pediatric patients with chemotherapy. A literature review was carried out in Redalyc, Ebsco and academic Google. There are drugs that can achieve significant improvements: cytoprotectors, misoprostol, benzidamina, it has been shown that hyperbolic oxygen has an effect on the inflammation of ulcers. Cryotherapy prevents and stops the progress of mucositis to a certain extent. There are natural agents and extracts wich have healing and medicinal properties that have anti-inflammatory actions and that act at the cellular level, reducing the signs and symptoms of mucositis. Mucositis in children can be altered by growth factors and cell turnover.
REFERENCES
Cuevas GM, Echeverría PE, Díaz AC. Trata-miento de la Mucositis Oral en pacientes On-cológicos. Revisión de la literatura y Expe-riencia en el Hospital General de México. Int Odontostomat. 2015; 9(2) 289 – 294.
Mora MD, Gómez GFJ, Yassin L, López JP, Vicente OV. Evaluación de terapias alterna-tivas en mucositis oral experimental. Av Odontoestomatol. 2016; 32 (6); 291-300.
Peña MC, Manso MB, González CR, Santi-llán GA, Febrero OA, Ortega BR. Cuidados de enfermería en la mucositis del pacienteoncológico: revisión de evidencias. Rev En-ferm 2017. 11(2).
Cardona A, Balouch A, Mohammed AM, Sedghizadeh PP, Reyes E. Efficacy of chlor-hexidine for the prevention and treatment of oral mucositis in cancer patients; a systema-tica review with meta-analyses. J oral pathol Med. 2017; 46; 680-688
Roisseau LG, Berad PM, Bolle S, Laurent S. Traitement des douleurs de mucite: actuali-tés et perspectives Treatment of mucositis pain: News and prospects. Elsevier, 2019: 106 (9) 77-783.
Berguer NH, Ugalde A. Mucositis oral aso-ciada a terapia oncológica. Revue Prescrire 2016: 36 (388): 116-118.
Grande BR, Apoite SM, Vallina FC, Merero C. Manejo Odontológico del paciente some-tido a radioterapia y cuello. RODOE, 2018; 13: 20-30
Mishra L, Nayak G. Effect of flavored (honey and tulsi) ice chips on reduction of oral mu-cositis among children receiving chemothe-rapy. Int. J. Pharm. Sci. Rev. Res. 2017, 43, 25-28.
Castejon N. Miel de manuk, un posible anti-bacteriano natural. [INTENET]. México 2018, Webconsultas,Healthcare S.A. [con-sultado diciembre 2020].Disponible en: https://www.webconsultas.com/curiosida-des/miel-de-manuka-un-posible-antibacte-riano-natural
Lalla RV, Bowen J, Barasch A, Elting L, EpsteinJ, Keefe DM, et al. Mucositis Guide-lines Leadership Group of the Multinational Association of supportive Care in Cancerand international Society of Oral Oncology (MASCC/ISOO). MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Can-cer. 2015: 120(10):1452-1461.
Riley P, McCabe M, Glenny A. Oral cryothe-rapy for preventing oral mucositis in patients receiving cancer treatment. JAMA Oncol. 2016; 2(10), 1365- 1366
Araújo S NM, Araújo HB, Freitas da SGR, Leite MAE, Moura RO. El paciente oncoló-gico con mucositis oral: desafíos para el cui-dado de enfermería. 2015 Rev. Latino-Am. Enfermagem: 267-274.
Episill Oral Liquid. Oral pain. [INTE-NET]. Camurus. Suecia. 2016; [consultado diciembre 2020]. Disponible en: https://www.episil.net/oral-pain/
Santos-Silva AR, Rosa GB, Eduardo CP, Dias RB, Brandao TB. Increased risk for ra-diation-related caries in cancer patients us-ing topical honey for the prevention of oral muco- sitis. Int J Oral Maxillofac Surg. 2011;40:1335-1336.
Bartolomé AA, Pardal RJL. Revisón sobre prevención y tratamiento de la mucositis oral en cancer de cabeza y cuello. Rev ORL, 2019; 4, 259-277.
Castañeda G. Probióticos, puesta al día: an update Rev Cub Pediatrica 018; 90 (2): 285-298.
El Bousaadani A. Actualités de la preven-tion et du traitement des mucites orales chezles enfants cancéreux: recommandatios pra-tiques. Cancer Radiother (2016); 20 (3) 226-230.
Costa RC, Limeira RRT, Carvalho LGA, Bo-nan PRF, Valenca AMG, Ribeiro ILA. Thera-peutic associatons on the management of chemo-induced oral mucositis in pediatric patients. REFACS. 2018;6(2): 256-263.
Memorial Sloan Ketterign Cancer Center. Mucosal coating agent. [INTENET] EUA. 2020. [consultado diciembre 2020]. Disponi-ble en https://www.mskcc.org/es/cancer-care/patient-education/mucosal-coating-agent
Piredda M, Facchinetti G, Biagioli V, Gianna-relli D, Armento G, Tonini G, et al. Propolis in the prevention of oral mucositis in breast cancer patients reveiving adjuvant chemot-herapy: A pilot radomised controlled trial Eur J cancer Care. 2017; 26(6): 1-8.
Münstedt K, Männle H. Using bee products for the prevention and treatment of oral mu-cositis inducen by cancer treatment. Molecu-les. 2019; 24(1); 1-13
Bennett MH, Feldmejer, J Hampson NB, Smee R, Milross C. Hyperbaic Oxygen the-rapy for late radiation issue injury. Cochrane 2016; 4(2): 1-8
Bonilla B, Jiménez H.Potencial industrial del Aloe Vera. Rev Cubana Farm 2016 Mar; 50(1): 139-150.
Mostafa S, Simin H, Mohsen M, Moghtada A, Mahnaz R, Armindokht S. Morphine mouthwash for the management of oral mu-cositis in patients with head and neck can-cer. Adv Biomed Res. 2015; 4: 44.
Ruiz G, Nervi V, Soni A. Tratamiento y pre-vencion de la mucositis oral asociada al tra-tamiento con del cancer. Rev Med Chile 2011; 139 (3):
Martinez PS. Lizosima en el tratamiento de la mucositis oral. Multimed 2021; 25 (4)1844.
Cuevas M, Echeverría E, Díaz C, Cuevas J. Tratamientos de la mucositis Oral en pacien-tes oncológicos: Revision de la literatura y Experiencia en el hospital general de Me-xico. Int. J. Odontostomat. 2015; 9(2): 289–294.
Navarro P, Leiva C, Donoso HF. Mucositis Oral: Actualización en el diagnóstico, Pre-vención y tratamiento. Int J Odontostomat. 2021; 15 (1): 263– 270.
Smith T. Gelclair: managing the sympotms of oral mucositis. Hosp Med. 2001 Oct;62(10):623-6
Lalla R, Solé S, Becerra S, Bettoli P, Letelier H. Efficacy and safety of Dentoxol, in the pre-vention of radiation-induced oral mucositis in head and neck cancer patients (ESDOM): a randomized, multicenter, double-Blind, pla-cebo-controlled, phase II, trial. Supp Care Cancer. 2020;28(12): 5871-9.
Calle A. Gonzalez M. Avances en las formu-laciones de los antisepticos. Ars Pharm. 2021; 62 (4): 451-470.
Jeldres M, Amarillo D, Lorenzo F, Cuello M. Patogenia y tratamiento de la mucositis aso-ciada al tratamiento de radioterapia y/o qui-mioterapia en pacientes con cancer de ca-beza y cuello. Rev Urug Med Int. 2021; 6(1): 4-13.
Beltrán Y, Reyes D, Flores M, Jaimes E. Ef-fect of parenteral glutamine in patients with gastrointestinal cancer undergoing surgery. Nutr Hosp. 2019; 36(1):5-12.
Montier A, Cabezas A, Díaz José C, linares E, Jerez E. Efecto de la vitamina e sobre an-tioxidants endógenos en ratas Wistar diabé-ticas. Rev Ciec Med. 2018; 27: 25-39
García S. La miel como alternativa a los tra-tamientos tópicos en el proceso de curación de quemaduras, heridas y úlceras. Ene. 2019; 13 (1): 1312.
Britzel M, Wasserman H, Henke M. Phase lll randomized trial of amifostine as radiopro-tector in head and neck cancer. J Clinic On-col 2000;18: 3339-3345
Del Valle L. Efecto in vitro de la Matricaria recutita L. sobre la respuesta de linfocitos y neutrófilos. Rev Cubana Hematol Inmunol Hemote. 2012; 28(2): 177-184
Vara A, Sosa R, Alayón C, Ayala N, Moreno G, Alayón V. Uso de la manzanilla en el tra-tamiento de enfermedades periodontales. AMC. 2019; 23(3): 403-414.
Souba W, Smith R, Wilmore D. Consumo in-testinal de combustibles administrados por vía intravenosa. J Parenter Enteral Nutr 1985;9:18-22
National Cancer Institute. FDA approval for palifermin [INTENET]. USA: NIH; 2015. [consultado diciembre 2020].Disponible en: https://www.cancer.gov/about-cancer/treat-ment