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ISSN 2448-8909 (Print)

2023, Number 5

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Med Crit 2023; 37 (5)

Risk factors associated with mortality in patients with severe acute respiratory distress syndrome due to COVID-19 in the Intensive Care Unit

Ortega PAQ, Vázquez PIM, Silva MMA, Ortega PJN

Language: Spanish
References: 20
Page: 384-387
PDF size: 181.45 Kb.


ABSTRACT

Introduction: multiple risk factors have been reported in certain populations around the world. In Spain, Intensive Care Unit (ICU) mortality was 31%, severe hypoxemia, higher sequential organic failure assessment scale (SOFA) score, as well as shock and arrhythmias; on the other hand, in China, obesity, age, serious comorbidities and the requirement for advanced respiratory support were reported. Finally, in the US they identified radiological and tomographic alterations like the most important factors associated with mortality. Material and methods: observational, cross-sectional and analytical study. Results: 193 patients were included, 50.5% died. The risk factors for mortality that were identified were: procalcitonin at day 10 (OR = 28.1, 95% CI 6.9-113.9, p < 0.001), septic shock (OR = 17.3, 95% CI 7.9-38.1, p < 0.001), high PEEP levels (OR = 3.7, 95% CI 2.5-5.5, p < 0.001) and pulmonary thromboembolism (OR = 4.7, 95% CI 1.001-22.6, p = 0.05). Finally, tracheostomy had a positive impact on mortality (OR = 0.1, 95% CI 0.04-0.35, p < 0.001). Conclusions: the factors associated with higher mortality were procalcitonin at day 10, septic shock and pulmonary thromboembolism; Tracheostomy was a protective factor for mortality.


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