2023, Number 3
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Rev Nefrol Dial Traspl 2023; 43 (3)
Acute encephalopathy due to severe hypophosphatemia
López-González-Gila JD, Rosales-Castillo A, Aguilar-Jaldo MP, Mañero-Rodríguez CA
Language: Spanish
References: 10
Page: 180-183
PDF size: 147.70 Kb.
ABSTRACT
Hypophosphatemia is a rare ionic
alteration that occurs mainly in
hospitalized patients. It is estimated
that up to 5 percent of them may have
low serum phosphate concentrations
(less than 2.5 mg / dL [0.80 mmol
/ L]). However, prevalences greater
than 30 to 50 percent have been
reported in alcoholic patients and/or
patients with severe sepsis or trauma. When combined with phosphate
depletion (that is, when it is not due
solely to phosphate movement into
cells), hypophosphatemia can cause
a variety of signs and symptoms,
primarily symptomatic when it is less
than 1 mg / dL. The leading causes
are divided into four points according
to their production mechanism:
internal redistribution, decreased
intestinal absorption, increased urinary
excretion, or elimination through renal
replacement techniques. We present
the case of a patient suffering from
unspecific acute encephalopathic
symptoms associated with severe
hypophosphatemia with adequate
evolution after its correction.
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