Laguna AC, Vilata Corell JJ, Martín González B

Language: Spanish
References: 16
Page: 255-262
PDF size: 479.73 Kb.

ABSTRACT

Acantholysis is the loss of cohesión between keratinocytes as a result of dissolution of intercellular desmosomal connections, resulting in clefts or intraepidermal vesicles. Acantholysis occurs classically in Hailey-Hailey’s disease, Darier´s disease, transient acantholytic dermatitis, group of penphi-gus, herpesvirus infection or warthy dysqueratoma. But acantholysis may also occurs in staphylococcal scalded skin syndrome, impetigo, acantholiticactinic keratosis, acantholytic squamous cell carcinoma or being an incidental finding or artifact. Focal incidental acantholysis has been noted as an incidental finding in association with bening and malignant epithelial lesions, fibrohistiocyticlesions, inflammatory lesions, melanocytic lesions and miscellaneous lesions. The pathologic changes either are observed within the lesion or in theimmediately adjacent epithelium. The cause of this clinically condition remains to be determined.

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