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Revista Médica Sinergia

2023, Number 08

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Revista Médica Sinergia 2023; 8 (08)

Narcolepsy: a syndrome of daytime sleepiness with an impact on quality of life

Quirós PF, Cornejo GJA

Language: Spanish
References: 16
Page:
PDF size: 137.19 Kb.


ABSTRACT

Narcolepsy is a clinical syndrome of daytime sleepiness with cataplexy, hypnagogic hallucinations, and sleep paralysis. It is one of the most common causes of disabling daytime sleepiness. There are two types, type 1 narcolepsy and type 2 narcolepsy. Its prevalence is the same for women as it is for men, and symptoms usually begins between 7 and 25 years; however, the diagnosis is often made years after the onset of symptoms. The treatment consists of behavioral therapy, as well as pharmacological treatment for both daytime sleepiness and cataplexy, in addition to implementing periodic and regular sleep times, establishing hours to sleep and taking scheduled daytime nap are essential measures in patients with this disorder.


REFERENCES

  1. Sum-Ping O, Mignot E. What is narcolepsy? JAMA [Internet]. 2023 [citado el 10 mayo 2023]. Disponible en: https://jamanetwork.com/journals/jama/fullarticle/2804848?resultClick=1

  2. Kliegman RM, Geme JW III, Blum N, Shah SS, Tasker RC, editores. Nelson. Tratado de Pediatría. 21a ed. Elsevier; 2020. p. 172-184.

  3. Latorre D, Sallusto F, Bassetti CLA, Kallweit U. Narcolepsy: a model interaction between immune system, nervous system, and sleep-wake regulation. Semin Immunopathol [Internet]. 2022 [citado el 10 mayo 2023];44(5):611–23. Disponible en: https://pubmed.ncbi.nlm.nih.gov/35445831/

  4. Hanin C, Arnulf I, Maranci J-B, Lecendreux M, Levinson DF, Cohen D, et al. Narcolepsy and psychosis: A systematic review. Acta Psychiatr Scand [Internet]. 2021 [citado el 10 mayo 2023];144(1):28–41. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33779983/

  5. Mignot E, Zeitzer J, Pizza F, Plazzi G. Sleep problems in narcolepsy and the role of hypocretin/orexin deficiency. Front Neurol Neurosci [Internet]. 2021 [citado el 10 mayo 2023];45:103–16. Disponible en: https://pubmed.ncbi.nlm.nih.gov/34052809/

  6. Anderson D. Narcolepsy: A clinical review. JAAPA [Internet]. 2021 [citado el 10 mayo 2023];34(6):20–5. Disponible en: https://pubmed.ncbi.nlm.nih.gov/34031309/

  7. Ollila HM. Narcolepsy type 1: what have we learned from genetics? Sleep [Internet]. 2020 [citado el 10 mayo 2023];43(11). Disponibleen: https://pubmed.ncbi.nlm.nih.gov/32442260/

  8. Mahoney CE, Cogswell A, Koralnik IJ, Scammell TE. The neurobiological basis of narcolepsy. Nat Rev Neurosci [Internet]. 2019 [citado el 10 mayo 2023];20(2):83–93. Disponible en: https://pubmed.ncbi.nlm.nih.gov/30546103/

  9. Thomas E. Scammell, MD. Clinical features and diagnosis of narcolepsy in adults. UpToDate. Wolters Kluwer Health. 2022 [citado el 10 mayo 2023]. Disponible en: https://www.uptodate.com/contents/clinical-features-and-diagnosis-of-narcolepsy-in-adults

  10. Truzzi G de M, Naufel MF, Tufik S, Coelho FM. Narcolepsy: the impact of aging, hypocretin deficiency, and years of formal education in olfactory function and abdominal obesity. Arq Neuropsiquiatr [Internet]. 2021 [citado el 10 mayo 2023];79(9):808–15. Disponible en: https://pubmed.ncbi.nlm.nih.gov/34495122/

  11. Aguera Ortiz L, Carrasco MM, Sánchez Pérez M, editores. Psiquiatría Geriátrica. 3a ed. Elsevier; 2021. p. 418-435.

  12. Gropper MA, Eriksson LI, Fleisher LA, Wiener-Kronish JP, Cohen NH, Leslie K, editores. Miller. Anestesia. 9a ed. Elsevier; 2021. p. 267-290.

  13. Borstnar CR, López FC, editores. Farreras Rozman. Medicina Interna. 19a ed. Elsevier; 2020. p.1337-1340.

  14. Bassetti CLA, Kallweit U, Vignatelli L, Plazzi G, Lecendreux M, Baldin E, et al. European guideline and expert statements on the management of narcolepsy in adults and children. J Sleep Res [Internet]. 2021 [citado el 10 mayo 2023];30(6):e13387. Disponible en: https://pubmed.ncbi.nlm.nih.gov/34173288/

  15. Thomas E. Scammell, MD. Treatment of narcolepsy in adults. UpToDate. Wolters Kluwer Health. 2022 [citado el 10 mayo 2023]. Disponible en: https://www.uptodate.com/contents/treatment-of-narcolepsy-in-adults

  16. Franceschini C, Pizza F, Cavalli F, Plazzi G. A practical guide to the pharmacological and behavioral therapy of Narcolepsy. Neurotherapeutics [Internet]. 2021 [citado el 10 mayo 2023];18(1):6–19. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33886090/




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