Serna-Calderón MA, Cervín-Báez C

Language: Spanish
References: 12
Page: 183-187
PDF size: 375.37 Kb.

ABSTRACT

Malignant melanoma is one of the most aggresive neoplasms of the skin. Four main subtypes of melanoma have been described: superficial spreading melanoma, nodular melanoma, lentigo maligna melanoma, and acral lentiginous melanoma. The etiology of melanoma is multifactorial, the incidence is higher in fair skinned population. The most important modifiable risk factor to develop melanoma is the exposure to ultraviolet radiation. Nodular melanoma is the second most common subtype of melanoma , nodular melanoma is characterized by early vertical growth rather than the typical initial radial growth of most melanomas. In nodular mela-noma, melanoma cells proliferate downwards through the skin. The lesion presents as a nodule (lump) that has been rapidly enlarging over the previous weeks to months. It can arise de novo or within an existing melanoma of another type. Surgical management of melanoma is planned according to diagnostic biopsy, wide local excision, and lymph node staging. Surgical resection of the tumor is the primary treatment of melanoma in all stages; the lesion should be completely excised with a 2-3 cm margin of normal tissue. Further treatment depends mainly on the Breslow thickness of the lesion. Even in its early stages nodular melanoma has the potential to metastasize to the vital organs.

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