2021, Number 4
Hypocalcemia, hypomagnesemia and chronic usage of proton-pump inhibitors
Language: Spanish
References: 14
Page: 1-11
PDF size: 557.42 Kb.
ABSTRACT
Introduction: Proton-pump inhibitors are drugs used in multiple gastropathies. Omeprazole belongs to this group of medicines; it is approved and classified as essential by the World Health Organization. This has permitted for its use to become constant and, to some extent, misleading. Despite being safe drugs, they show side effects, among which an occasional one is fluid and electrolyte disorders.Objective: To present a clinical case in which the occurrence of side effects was verified after the administration of a drug constantly used by the medical community.
Clinical case: The following is a clinical case of a male patient with a history of arterial hypertension and chronic gastropathy, characterized by the usage of proton-pump inhibitors for eight consecutive years, diagnosed with hypomagnesemia and hypocalcemia. Normal laboratory results were obtained after oral supplementation and usage of ranitidine with suppression of omeprazole therapy.
Conclusions: Constant control of the drugs used by chronic patients is essential in primary health care. The usage of proton-pump inhibitors has become a routine. It is always necessary to check the dose and time for using the drugs as well as the relationship with other drugs used by the patient.
REFERENCES
Sánchez L, Nombela A, Velázquez C, Hernández S, Carretón M. Efectos adversos del consumo crónico de omeprazol. FMC: Formación Médica Continuada en Atención Primaria. 2016 [acceso: 11/09/2020];23(7):416-9. Disponible en: Disponible en: https://www.fmc.es/es-efectos-adversos-del-consumo-cronico-articulo-S1134207216302432 .
Emura M, Agüirre M, Cardona D, García M, García D, Gutiérrez E, et al. Prescripción-indicación de los inhibidores de la bomba de protones. Costo de la prescripción inadecuada en un primer nivel en Colombia. Acta Médica Colombiana. 2018 [acceso: 11/09/2020];43(4):183-91. Disponible en: Disponible en: http://www.actamedicacolombiana.com/ojs/index.php/actamed/article/view/1264 .
Cardona J, Medina D, Rodríguez A, Machado J. Efectos adversos a largo plazo de los inhibidores de la bomba de protones. Perspectiva desde la medicina basada en la evidencia. Revista Colombiana de Gastroenterología. 2016 [acceso: 18/09/2020];31(4):403-8. Disponible en: Disponible en: http://www.scielo.org.co/scielo.php?pid=S0120-99572016000400010&script=sci_abstract&tlng=es
Shabaka A, Tornero F, del Castillo S, Rodríguez R, Romero S, Gil B, et al. Trastornos electrolíticos graves asociados a tratamiento crónico con omeprazol. Nefrología (English Edition). 2016 [acceso: 20/09/2020];8(1):89-93. Disponible en: Disponible en: https://www.revistanefrologia.com/en-trastornos-electroliticos-graves-asociados-tratamiento-articulo-X1888970016558019