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2021, Number 4

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Rev Cubana Hematol Inmunol Hemoter 2021; 37 (4)

Gastrointestinal bleeding in the context of isolated factor VII deficiency: case report

Altamirano-Molina M, Rivera-Pinto AX, Díaz-Torres CJ, Araujo-Banchon WJ

Language: Spanish
References: 16
Page: 1-9
PDF size: 262.96 Kb.


ABSTRACT

Introduction: Little is known about the acquired form of factor VII deficiency and few cases are reported in the literature.
Objective: To present a case of a patient with an isolated deficit of factor VII, in the context of low gastrointestinal bleeding.
Presentation of the case: 82-year-old Peruvian woman who comes to the emergency room for presenting with lower GI bleeding. Prolonged prothrombin time and isolated factor VII deficiency are detected during routine examinations. There were no evidence of pathological mechanisms of vitamin K deficiency or malabsorption, anticoagulant therapy with vitamin K antagonists, hyperfibrinolysis, or disseminated intravascular coagulation. She responded to the treatment with fresh frozen plasma and the normal results of the hematological test carried out on the sister remove the possible hereditary etiology.
Conclusion: This Peruvian case of isolated factor VII deficit, in the context of low gastrointestinal bleeding, allows adding information to the limited Latin American evidence.


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