2023, Number 06
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Ginecol Obstet Mex 2023; 91 (06)
Venous sinus thrombosis in a patient during the immediate puerperium. Case report
Salazar-Trujillo JC, Paladino-Barquera G, Siu-Moguel G, Rivas-Dow A, López-Ortiz CS
Language: Spanish
References: 20
Page: 432-439
PDF size: 1260.66 Kb.
ABSTRACT
Background: Venous sinus thrombosis accounts for 1% of cerebral vascular events;
its incidence is 5 cases per million population and its mortality is 10%. The superior
sagittal and transverse venous sinuses are the most affected. Pregnancy is a special risk
factor since thrombosis is registered in 0.01% of pregnancies.
Clinic case: A 40-year-old primigravida patient with a 33.6 week biamniotic
twin pregnancy. She was admitted to the Emergency Department due to the diagnosis
of preeclampsia with severity criteria, with blood pressure of 160-100 mmHg and
transaminasemia. She was prescribed antihypertensive treatment and intravenous
magnesium sulfate. It was decided to terminate the pregnancy by cesarean section.
On the fourth post-cesarean day she had decreased strength in both arms, loss of
muscle tone in the pelvic limbs, holocranial headache and altered alertness (Glasgow
of 14). Magnetic resonance imaging showed occlusion of the superior longitudinal
sinus and ischemia in the left parietooccipital region. He was administered anticoagulants
and analgesics with which he evolved adequately; he was discharged
without complications.
Conclusions: Venous sinus thrombosis implies a challenge when there is no high
diagnostic suspicion in patients with neurological signs and symptoms and, even more
so, when prothrombotic risk factors are added, such as pregnancy and puerperium.
Timely diagnosis provides the opportunity to initiate appropriate treatment and reduce
symptoms and comorbidities.
REFERENCES
Luo Y, Tian X, Wang X. Diagnosis and Treatment of CerebralVenous Thrombosis: A Review. Front Aging Neurosci 2018;10: 2. doi: 10.3389/fnagi.2018.00002
Kiliç T, Akakin A. Anatomy of cerebral veins and sinuses. FrontNeurol Neurosci 2008; 23: 4-15. doi:10.1159/000111256
Stam J. Thrombosis of the cerebral veins and sinuses.N Engl J Med 2005; 352 (17): 1791-98. doi:10.1056/NEJMra042354
Idiculla PS, Gurala D, Palanisamy M, Vijayakumar R,Dhandapani S, Nagarajan E. Cerebral venous thrombosis:a comprehensive review. Eur Neurol 2020; 83 (4): 369-79.doi:10.1159/000509802
Ferro JM, Canhão P, Stam J, Bousser MG, BarinagarrementeriaF; ISCVT Investigators. Prognosis of cerebral vein anddural sinus thrombosis: results of the International Studyon Cerebral Vein and Dural Sinus Thrombosis (ISCVT).Stroke 2004; 35 (3): 664-70. doi: 10.1161/01
Cruz-Hernández V, León-Tapia S, López-Gómez P, Cruz-Acevedo DA, Arango-Díaz A. Trombosis del seno venosocerebral durante el puerperio. Medicina interna de México2018; 34 (3): 388-393. https://doi.org/10.24245/mim.v34i3.1916
Saadatnia M, Fatehi F, Basiri K, Mousavi SA, Mehr GK.Cerebral venous sinus thrombosis risk factors. Int J Stroke2009; 4 (2): 111-23. doi:10.1111/j.1747-4949
Kashkoush AI, Ma H, Agarwal N, Panczykowski D, Tonetti D,Weiner GM, Ares W, Kenmuir C, Jadhav A, Jovin T, JankowitzBT, Gross BA. Cerebral venous sinus thrombosis in pregnancyand puerperium: A pooled, systematic review. J ClinNeurosci 2017; 39: 9-15. doi:10.1016/j.jocn.2017.02.046
Uluduz D, Sahin S, Duman T, Ozturk S, Yayla V, Afsar N.Cerebral venous sinus thrombosis in women: subgroupanalysis of the VENOST study. Stroke Res Treat 2020; 2020:8610903. doi:10.1155/2020/8610903
Gao L, Xu W, Li T, Yu X, Cao S, Xu H, Yan F, Chen G. Accuracyof magnetic resonance venography in diagnosing cerebralvenous sinus thrombosis. Thromb Res 2018; 167: 64-73.doi:10.1016/j.thromres.2018.05.012
Bertani R, Rodrigues RB, Koester SW, Vasconcelos FA, MonteiroR. Complicated cerebral venous thrombosis during thefirst trimester of pregnancy. Cureus 2020; 12 (9): e10683.doi:10.7759/cureus.10683
Liang ZW, Gao WL, Feng LM. Clinical characteristics andprognosis of cerebral venous thrombosis in Chinese womenduring pregnancy and puerperium. Sci Rep 2017; 7: 43866.doi:10.1038/srep43866
Stam J. Thrombosis of the cerebral veins and sinuses. N EnglJ Med 2005; 352 (17): 1791-8. doi:10.1056/NEJMra042354
Al Hashmi K, Al Wahaibi K, Al-Khabori M, Al Lamki S.Characteristics and Outcomes of Patients with CerebralVenous Sinus Thrombosis. Oman Med J 2019; 34 (5): 434-37. doi:10.5001/omj.2019.79
Chu X, Zhang J, Zhang B, Zhao Y. Analysis of age andprevention strategy on outcome after cerebral venousthrombosis. Biomed Res Int 2020; 2020: 6637692. doi:10.1155/2020/6637692
Bousser MG. Cerebral venous thrombosis: diagnosis andmanagement. J Neurol 2000; 247 (4): 252-8. doi:10.1007/s004150050579
Ferro JM, Bousser MG, Canhão P, Coutinho JM, CrassardI, Dentali F, et al. European Stroke Organization. EuropeanStroke Organization guideline for the diagnosis andtreatment of cerebral venous thrombosis - endorsed bythe European Academy of Neurology. Eur J Neurol 2017;24 (10): 1203-13. doi:10.1111/ene.13381
Ferro JM, Aguiar de Sousa D. Cerebral venous thrombosis:an update. Curr Neurol Neurosci Rep 2019; 19 (10): 74.doi:10.1007/s11910-019-0988-x
Perkin GD. Cerebral venous thrombosis: medicaltherapy. JR Soc Med 2000; 93 (5): 238-40.doi:10.1177/014107680009300506
Liang ZW, Gao WL, Feng LM. Clinical characteristics andprognosis of cerebral venous thrombosis in Chinese womenduring pregnancy and puerperium. Sci Rep. 2017; 7: 43866.doi:10.1038/srep43866