2021, Number 6
Epidemiological, clinical and imaging profile of Multiple Sclerosis
Language: Spanish
References: 19
Page: 948-958
PDF size: 369.27 Kb.
ABSTRACT
Background: multiple sclerosis is a neurological, autoimmune, degenerative, chronic and progressive demyelinating disease associated with different genetic and environmental factors.Objective: to characterize epidemiologically, clinically and imaging patients with a diagnosis of multiple sclerosis.
Methods: observational, descriptive, cross-sectional study on all patients with a diagnosis of multiple sclerosis with follow-up at the Arnaldo Milián Castro Provincial University Clinical-Surgical Hospital, in Villa Clara during the period from January 2014 to December 2019. The epidemiological variables analyzed: sex, age of disease onset, skin color, place of origin; clinical variables: symptoms at the beginning and at present; number of shoots; years of evolution, clinical forms; Imaging variables: number of lesions, location, atrophy or change in signal intensity of the corpus callosum and McDonald's criterion fulfilled.
Results: there was a higher incidence of females with 80 patients. It was found that 59 patients had a relapsing-remitting clinical form, 21 patients had a secondary progressive form, 4 patients had a primary progressive and 2 patients had a relapsing progressive one. Symptoms: motor deficit, sensory deficit and cerebellar alterations were the most frequent at the beginning and at present. Disability evaluated as minimal was found in 50 patients and 31 patients had 2 to 4 lesions on nuclear magnetic resonance.
Conclusions: Adequate epidemiological information on patients with multiple sclerosis in Villa Clara was obtained satisfactorily. It is important to consider this report as a basis for decision-making on issues of projection of treatment and care, aspects of great importance in high-cost diseases, such as multiple sclerosis.
REFERENCES
Fernández Fernández O, Saiz Hinarejos A. Enfermedades desmielinizantes del sistema nervioso central. En: Rozman Borstnar C, Cardellach López F. Medicina Interna[Internet]. Madrid: Elsevier; 2016. p. 1381-91. Disponible en: https://www.clinicalkey.es/service/content/pdf/watermarked/3-s2.0-B978849022996500171X.pdf?locale=es_ES
Bertado Cortés B, Villamil Osorio L, Carrera Pineda R, Martínez Cortés C, Guerrero Canter J. Características clínicas y demográficas de los pacientes con esclerosis múltiple. Rev Med Inst Mex Seguro Soc[Internet]. 2016[citado 20/05/2019];54(Sup 2):[aprox. 5 p.]. Disponible en: https://www.medigraphic.com/pdfs/imss/im-2016/ims162j.pdf
Thompson AJ, Banwell BL, Barkhof F, Carroll WM, Coetzee T, Comi G. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. The Lancet Neurology. [Internet]. 2018[citado 20/05/2019];17(2):62-173. Disponible en: http://discovery.ucl.ac.uk/10041020/1/Barkhof_Diagnosticcriteria_revision1_final_10OCT2017.pdf
Mohammed E. Multiple sclerosis is prominent in the Gulf states: Review. Pathogenesis [Internet]. 2016[citado 20/05/2019];3:[aprox. 20 p.]. Disponible en: http://ac.els-cdn.com/S2214663616300049/1-s2.0-S2214663616300049-main.pdf?_tid=3154a542-455a-11e7-9672-00000aab0f01&acdnat=1496164113_6486264bb1d09bf35dc086211565c493
Rojas E, Alva A, Montalvan V. Cambios clínicos de la esclerosis múltiple según modificación de los criterios de McDonald. Hospital Almenara, 2001-2015. An Fac Med [Internet]. 2019[citado 20/02/2020];80(1):[aprox. 14 p.] Disponible en: https:/www.scielo.org.pe/scielo.php?scrip=sci_arttext&pid=S1025-55832019000100006.
Gracia F, Armién B, Rivera V, Valverde A, Rodríguez V, Monterrey P, et al. Multiple Sclerosis in Central American and Spanish Caribbean Region: Should it be Recognized as a Public Health Problem?, Collaborative Multiple Sclerosis Group of Central America and Spanish Caribbean Region (CMSG). J Epid Prev Med. 2017; 3:134.
Bsteh G, Ehling R, Lutterotti A, Hegen H, Di Pauli F, Auer M, Deisenhammer F, Reindl M, Berger T. Long Term Clinical Prognostic Factors in Relapsing-Remitting Multiple Sclerosis: Insights from a 10-Year Observational Study. PLoS One[Internet]. 2016[citado 20/02/2020];11(7):[aprox. 18 p.] Disponible en: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0158978&type=printable
Correa P, Ortiz A, Torres G, Buestan M, Martinez B, Paredes V, Jácome C, Vásconez V, Zambrano J, Flores E, Benalcázar E, Barros J, Acosta C. The Clinical and Epidemiological Spectrum of Multiple Sclerosis in Quito,Ecuador. J Neurol Disord[Internet]. 2016[citado 20/02/2020];4(7):[aprox. 17 p.] Disponible en: https://www.researchgate.net/publication/309876930_The_Clinical_and_Epidemiological_Spectrum_of_Multiple_Sclerosis_in_Quito_Ecuador