2006, Number 5
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Med Cutan Iber Lat Am 2006; 34 (5)
Cutaneous hemangiomas. A clinicopathological analysis with special emphasis in novel microscopic findings
Solís LG, Moreno LLM, Peniche RJ, Mercadillo PP
Language: Spanish
References: 17
Page: 208-215
PDF size: 296.92 Kb.
ABSTRACT
Hemangiomas are the most frequent vascular skin neoplasms, but there are no studies defining their frequency.
Objectives: To determine the frequency of presentation in the different cutaneous hemangiomas in biopsy specimens submitted to our service, and to verify the level of clinicopathological correlation established in cutaneous hemangiomas.
Methods: Archives of biopsy reports and specimens of any kind of cutaneous hemangiomas submitted in a ten year period.
Results: In a ten year period, 18.142 biopsies were submitted, which 520 specimens (2.86%) belonging to the hemangioma category. The most frequent tumor was pyogenic granuloma (56.5%), followed by capillary hemangioma (17.5%), cherry hemangioma (10%) and venous hemangioma (7.1%). Other hemangiomas were less common. We found hobnail endothelial cells in pyogenic granuloma (n = 68), capillary hemangiomas (n = 6) and venous hemangiomas (n = 6). We described some mixed (collision tumors) hemangiomas.
Conclusions: In cutaneous biopsy specimens, pyogenic granuloma was the most frequent vascular benign neoplasm; followed by capillary heman-gioma (adult type), cherry angioma and venous hemangioma. Other tumors are uncommon. We found some collision tumors (capillary and venous hemangioma, hemangioma and intradermal melanocytic nevus). The finding of hobnail cells in cutaneous hemangiomas is a novel finding and its clinical significance remains obscure. The clinicopathological correlation of cutaneous hemangiomas (beside from pyogenic granuloma) remains very low.
REFERENCES
1.Requena L, Sangueza OP. Cutaneous vascular proliferations. Part I: Hamartomas, malformations and dilatation of preexisting vessels. J Am Acad Dermatol 1997; 37: 523-49.
2.Requena L, Sangueza OP. Cutaneous vascular proliferations. Part II: Hyperplasias and benign neoplasms. J Am Acad Dermatol 1997; 37: 887- 920.
3.Requena L, Sangueza OP. Cutaneous vascular proliferations. Pat III: Malignant neoplasms, other cutaneous neoplasms with significant vascular component and disorders erroneously considered as vascular neoplasms. J Am Acad Dermatol 1998; 38:143- 75.
4.Kempson RL, Fletcher CDM, Evans HL, Hendrickson MR, Sibley RK. Atlas of Tumor Pathology. Tumors of soft tissues. Washington: Universities Associated for Research and Education in Pathology, Inc. 2001; pp. 307-70.
5.Benign tumors and tumor-like lesions of blood vessels. En: Weiss SW, Goldblum JR editors. Enzinger and Weiss’s Soft Tissue tumors. 4th ed. St Louis: Mosby, 2003; pp. 837-890.
Hunt SJ, Santa Cruz DJ, Barnhill RL. Vascu-lar tumors. En: Barnhill Rl (editor). Textbook of Dermatopathology. New York; Mc-Graw Hill, 2004; pp. 821-70.
7.Harris MN, Desai R, Chuang T-Y, Hood AF, Mirowski GW. Lobular capillary hemangiomas: an epidemiologic report, with emphasis on cutaneous lesions. J Am Acad Dermatol 2000;42:1012-6.
8.Pagliai KA, Cohen BA. Pyogenic granuloma in children. Pediatr Dermatol 2004;21:10-3.
9.Patrice SJ, Wiss K, Mulliken JB. Pyogenic granuloma (lobular capillary hemangioma): a clinicopathological study of 178 cases. Pediatr Dermatol 1991;8: 267-76.
Calonje E, Wilson-Jones E. Tumores vascula-res. En: Elder D, Elenitsas R, Jaworsky C, Jonson B Jr. Lever Histopatología de la piel, 8ª. Edición Buenos Aires: Intermédica, 1997; pp. 769-808.
Cooper PH. Vascular tumors. En: Farmer E, Hood A. editors. Pathology of the skin. Norwalk: Appleton & Lange, 1990; pp. 804-846.
12.Firooz A, Komeili A, Dowlati Y. Eruptive melanocytic nevi and cherry angiomas secondary to exposure to sulfur mustard gas. J Am Acad Dermatol 1999; 40: 646-7.
Requena L, Kutzner H, Mentzel T. Acquired elastotic hemangioma: a clinicopathologic variant of hemangioma. J Am Acad Dermatol 2002;47:371-6.
Kim YC, Park HJ, Cinn YW. Microvenular hemangioma. Dermatology 2003;206: 161-4.
Hemangioendothelioma: vascular tumors of intermediate malignancy. En: Weiss SW, Goldblum JR editors. Enzinger and Weiss’s Soft Tissue tumors. 4th ed. St Louis: Mosby, 2003; pp. 891-915.
16.Santa Cruz DJ, Aronberg J. Targetoid hemosiderotic hemangioma. J Am Acad Dermatol 1988;19:550-8.
17.Nayler S, Rubin B, Calonje E. Composite hemangioendothelioma: a complex, low-grade vascular lesion mimicking angiosarcoma. Am J Surg Pathol 2000; 24: 352-61.