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2022, Number 6

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Salud Mental 2022; 45 (6)

Fear of cancer recurrence in informal caregivers of childhood cancer survivors

Espinoza-Salgado FS, Landa-Ramírez E, Robles R

Language: English
References: 69
Page: 319-326
PDF size: 265.96 Kb.


ABSTRACT

Background. Fear of cancer recurrence is one of the most distressing psychological consequences in cancer survivors and their informal primary caregivers (IPC). IPC of childhood cancer survivors (CCS) are often their mothers, which could intensify fear of cancer recurrence (FCR) and its impact on both IPC and CCS. However, the phenomenon has not been widely described in this specific population. Objective. To summarize and analyze current evidence on the evaluation and management of FCR among IPC of CCS. Method. A narrative review of studies included in four databases (PsycInfo, Medline, CINALH, and Web of Science) with no language or year of publication restrictions. Results. Measures specifically developed to assess FCR among IPC of CCS comprising an interview and a questionnaire with initial psychometric evaluations and two short, online intervention programs based on cognitive-behavioral-contextual therapy were identified (ENGAGE and CASCAdE). Both have demonstrated acceptability in parents of CCS in high-income countries; preliminary evidence also exists of the effectivity of CASCAdE in reducing FCR. Discussion and conclusion. Given the limitations of this area of psychological evaluation, the Fear of Cancer Recurrence Inventory, originally developed for adult cancer survivors, constitutes the most suitable tool for evaluating FCR among IPC of CCS. The CASCAdE program seems a promising intervention for IPC of CSS, although cultural adaptations, evaluations of its acceptability in low- and middle-income countries, and controlled studies in large samples are still required.


REFERENCES

  1. Abate, C., Lippé, S., Bertout, L., Drouin, S., Krajinovic, M., Rondeau, É., … Sultan,S. (2018). Could we use parent report as a valid proxy of child report on anxiety,depression, and distress? A systematic investigation of father-mother-childtriads in children successfully treated for leukemia. Pediatric Blood & Cancer,65(2). doi: 10.1002/pbc.26840

  2. Altuve, J. J. (2020). Distrés psicológico, miedo a la recurrencia del cáncer y calidad devida relacionada con la salud en sobrevivientes de cáncer de mama venezolanas.Psicooncología, 17, 239-253. doi: 10.5209/psic.72019

  3. Bhatia, S., Landier, W., Casillas, J., & Zeltzer, L. (2006). Medical and PsychosocialIssues in Childhood Cancer Survivors. In A. E. Chang, D. F. Hayes, H. I. Pass,R. M. Stone, P. A. Ganz, T. J. Kinsella, J. H. Schiller, & V. J. Strecher (Eds.),Oncology an evidence-based approach (pp. 1801-1813). Nueva York, NY:Springer. doi: 10.1007/0-387-31056-8_102

  4. Butow, P., Sharpe, L., Thewes, B., Turner, J., Gilchrist, J., & Beith, J. (2018). Fear ofCancer Recurrence: A Practical Guide for Clinicians. Oncology (Williston Park,N.Y.), 32(1), 32-38.

  5. Carreño-Moreno, S., Chaparro-Díaz, L., & Blanco-Sánchez, P. (2017) Cuidadorfamiliar del niño con cáncer: Un rol en transición. Revista Latinoaméricana deBioética, 17(2), 18-30. doi: 10.18359/rlbio.2781

  6. Chen, D., Sun, W., Liu, N., Wang, J., Zhao, J., Zhang, Y., … Zhang, W., (2018). Fearof Cancer Recurrence: A Systematic Review of Randomized, Controlled Trials.Oncology Nursing Forum, 45(6), 703-712. doi: 10.1188/18.ONF.703-712

  7. Cupit-Link, M., Syrjala, K. L., & Hashmi, S. K. (2018). Damocles’ syndromerevisited: Update on the fear of cancer recurrence in the complex world oftoday’s treatments and survivorship. Hematology/Oncology and Stem CellTherapy, 11(3), 129-134. doi: 10.1016/j.hemonc.2018.01.005

  8. DeVellis, R. F. (2017). Scale development: Theory and application. California: SagePublications.

  9. Duran, B. (2011). Developing a Scale to Measure Parental Worry and Their AttitudesToward Childhood Cancer After Successful Completion of Treatment: Apilot study. Journal of Pediatric Oncology Nursing, 28(3), 154-168. doi:

  10. 10.1177/104345421039775510. Ernst, M., Brähler, E., Klein, E. M., Jünger, C., Wild, P. S., Faber, J., … Beutel,M. E. (2020). What’s past is prologue: Recalled parenting styles are associatedwith childhood cancer survivors’ mental health outcomes more than 25 yearsafter diagnosis. Social Science & Medicine, 252, 112916. doi: 10.1016/j.socscimed.2020.112916

  11. Fardell, J. E., Thewes, B., Turner, J., Gilchrist, J., Sharpe, L., Smith, A., … Butow,P. (2016). Fear of cancer recurrence: a theoretical review and novel cognitiveprocessing formulation. Journal of Cancer Survivorship, 10(4), 663-673. doi:10.1007/s11764-015-0512-5

  12. Ferlay, J., Colombet, M., Soerjomataram, I., Mathers, C., Parkin, D. M., Piñeros,M., … Bray, F. (2019). Estimating the global cancer incidence and mortalityin 2018: GLOBOCAN sources and methods. International Journal of Cancer,144(8), 1941-1953. doi: 10.1002/ijc.31937

  13. Fitch, M. I., Sharp, L., Hanly, P., & Longo, C. J. (2021). Experiencing financialtoxicity associated with cancer in publicly funded healthcare systems: asystematic review of qualitative studies. Journal of Cancer Survivorship:Research and Practice, 16, 314-328. doi: 10.1007/s11764-021-01025-7

  14. Furr, M. (2018). Psychometrics: An Introduction (3rd Ed.). Los Angeles: Sage.

  15. Hanratty, B., Holland, P., Jacoby, A., & Whitehead, M. (2007). Financial stress andstrain associated with terminal cancer--a review of the evidence. PalliativeMedicine, 21(7), 595-607. doi: 10.1177/0269216307082476

  16. Hayes, S. C., Strosahl, K., & Wilson, K. G. (2015) Terapia de aceptación ycompromiso: proceso práctica del cambio consiente (mindfulness). Bilbao,España: Descleé de Brouwer.

  17. Holosbach, G., & Solares, T. (2010). Experiences of caregiver of children andteenagers with cancer. Serie: Ciencias da Saúde, 11(1), 89-108.

  18. Instituto Nacional de Estadística y Geografía [INEGI]. (2020). INEGI Estadísticasa propósitos del día mundial del internet, datos nacionales. Retrieved fromhttps://www.inegi.org.mx/contenidos/saladeprensa/aproposito/2020/eap_internet20.pdf

  19. International Test Commission [ITC]. (2013). ITC Guidelines on Test Use (ITC-GTU-

  20. 20131008). Retrieved from https://www.intestcom.org/files/guideline_test_use.pdf20. Iwai, N., Shimada, A., Iwai, A., Yamaguchi, S., Tsukahara, H., & Oda, M. (2017).Childhood cancer survivors: Anxieties felt after treatment and the need forcontinued support. Pediatrics International: Official Journal of the JapanPediatric Society, 59(11), 1140-1150. doi: 10.1111/ped.13390

  21. Kalra, H., Kamath, P., Trivedi, J. K., & Janca, A. (2008). Caregiver burden inanxiety disorders. Current Opinion in Psychiatry, 21(1), 70-73. doi: 10.1097/yco.0b013e3282f2dfca

  22. Kazak, A., Alderfer, A., Streisand, R., Simms, S., Rourke, M., Barakat, L., … Cnaan,A. (2004). Treatment of Posttraumatic Stress Symptoms in Adolescent Survivorsof Childhood Cancer and Their Families: A Randomized Clinical Trial. Journalof Family Psychology, 18(3), 493-504. doi: 10.1037/0893-3200.18.3.493

  23. Kazak, A., Simms, S., Barakat, L., Hobbie, W., Foley, B., Golomb, V., … Best,M. (1999). Surviving Cancer Competently Intervention Program (SCCIP):A Cognitive-Behavioral and Family Therapy Intervention for AdolescentSurvivors of Childhood Cancer and Their Families. Family Process, 38(2), 176-191. doi: 10.1111/j.1545-5300.1999.00176.x

  24. Kearney, J. A., Salley, C. G., & Muriel, A. C. (2015). Standards of Psychosocial Carefor Parents of Children with Cancer. Pediatric Blood & Cancer, 62(Suppl 5),S632-683. doi: 10.1002/pbc.25761

  25. Klassen, A. F., Klaassen, R., Dix, D., Pritchard, S., Yanofsky, R., O’Donnell, M., …Sung, L. (2008). Impact of caring for a child with cancer on parents’ healthrelatedquality of life. Journal of Clinical Oncology: Official Journal of theAmerican Society of Clinical Oncology, 26(36), 5884-588. doi: 10.1200/JCO.2007.15.2835

  26. Koyanagi, A., DeVylder, J. E., Stubbs, B., Carvalho, A. F., Veronese, N., Haro, J.M., & Santini, Z. I. (2018). Depression, sleep problems, and perceived stressamong informal caregivers in 58 low-, middle-, and high-income countries: Across-sectional analysis of community-based surveys. Journal of PsychiatricResearch, 96, 115-123. doi: 10.1016/j.jpsychires.2017.10.001

  27. Kuba, K., & Weißflog, G. (2017). Acceptanceand Commitment Therapy in theTreatmentof ChronicDisease. Psychotherapie, Psychosomatik,MedizinischePsychologie, 67(12), 525-536. doi: 10.1055/s-0043-118742

  28. Kurt, B. A., Nolan, V. G., Ness, K. K., Neglia, J. P., Tersak, J. M., Hudson, M. M., …Arora, M. (2012). Hospitalization rates among survivors of childhood cancer inthe Childhood Cancer Survivor Study cohort. Pediatric Blood & Cancer, 59(1),126-132. doi: 10.1002/pbc.24017

  29. Lebel, S., Maheu, C., Lefebvre, M., Secord, S., Courbasson, C., Singh, M., … Catton,P. (2014). Addressing fear of cancer recurrence among women with cancer: afeasibility and preliminary outcome study. Journal of Cancer Survivorship:Research and Practice, 8(3), 485-496. doi: 10.1007/s11764-014-0357-3

  30. Lin, C. R., Chen, S. C., Chang, J. T., Fang, Y. Y., & Lai, Y. H. (2016). Fear of cancerrecurrence and its impacts on quality of life in family caregivers of patientswith head and neck cancers. Journal of Nursing Research, 24(3), 240-248. doi:10.1097/jnr.0000000000000169

  31. Lin, C. R., Chen, S. C., Simard, S., Chang, J. T., & Lai, Y. H. (2018). Psychometrictesting of the Fear of Cancer Recurrence Inventory-caregiver Chinese version incancer family caregivers in Taiwan. Psycho-Oncology, 27(6), 1580-1588. doi:10.1002/pon.4697

  32. Manterola, C., Astudillo, P., Arias, E., Claros, N., & Grupo MINCIR. (2013)Revisiones sistemáticas de la literatura. Qué se debe saber acerca de ellas.Cirugía Española, 91(3), 149-155. doi: 10.1016/j.ciresp.2011.07.009

  33. Marcus, A. (March 24, 2004). Debate heats up on defining a cancer survivor.The Wall Street Journal. Retrieved from https://www.wsj.com/articles/SB108008897185563641

  34. Marzorati, C., Riva, S., & Pravettoni, G. (2017). Who Is a Cancer Survivor? ASystematic Review of Published Definitions. Journal of Cancer Education,32(2), 228-237. doi: 10.1007/s13187-016-0997-2

  35. McGinty, H. L., Goldenberg, J. L., & Jacobsen, P. B. (2012) Relationship of threatappraisal with coping appraisal to fear of cancer recurrence in breast cancersurvivors. Psycho-Oncology, 21(2), 203-210. doi: 10.1002/pon.1883

  36. Mellon, S., Kershaw, T. S., Northouse, L. L., & Freeman-Gibb, L. (2007). A familybasedmodel to predict fear of recurrence for cancer survivors and theircaregivers. Psycho-Oncology, 16(3), 214-223. doi: 10.1002/pon.1074

  37. Mitchell, A. J. (2007). Pooled results from 38 analyses of the accuracy of distressthermometer and other ultra-short methods of detecting cancer-related mooddisorders. Journal of Clinical Oncology, 25(29), 4670-4681. doi: 10.1200/JCO.2006.10.0438

  38. Montero, X. (2013). Valoración integral y factores de cambio en la carga decuidadores primarios informales de niños con cáncer (Doctoral dissertation).Retrieved from http://www.ciencianueva.unam.mx/xmlui/handle/123456789/83

  39. Montero, X., Espinoza, F., Bravo, M., & Méndez, J. (2017) Ansiedad en Cuidadoresprimarios informales de niños y adultos con cáncer. In: C. Roja & Y. Gutiérrez(Eds.). Psicooncología 2: Enfoques, Avances e Investigación (pp. 297-318).Chile: Nueva Mirada Ediciones. Retrieved from https://dialnet.unirioja.es/servlet/libro?codigo=851170

  40. Montero, X., Jurado, S., & Méndez, J. (2014). Carga, ansiedad y depresión encuidadores primarios informales de niños con cáncer. Psicología y Salud, 24(1),45-53

  41. Nam, G. E., Warner, E. L., Morreall, D. K., Kirchhoff, A. C., Kinney, A. Y., &Fluchel, M. (2016). Understanding psychological distress among pediatriccancer caregivers. Supportive Care in Cancer, 24(7), 3147-3155. doi: 10.1007/s00520-016-3136-z

  42. National Cancer Institute [NCI]. (2020). Cancer Diccionary. Retrieved from https://www.cancer.gov/espanol/publicaciones/diccionario/ampliar/S

  43. Northouse, L. L. (1981). Mastectomy patients and the fear of cancer recurrence.Cancer Nursing, 4(3), 213-220. doi: 10.1097/00002820-198106000-00004

  44. Nunally, J., & Bernstein, I. (1994). Psychometric Theory (3rd Ed.). New York:McGraw-Hill.

  45. Oeffinger, K. C., Hudson, M. M., & Landier, W. (2009). Survivorship: Childhoodcancer survivors. Primary Care: Clinics in Office Practice, 36(4), 743-780. doi:10.1016/j.pop.2009.07.007

  46. Oeffinger, K. C., Mertens, A. C., Sklar, C. A., Kawashima, T., Hudson, M. M.,Meadows, A. T., … Childhood CancerSurvivorStudy. (2006). Chronic healthconditions in adult survivors of childhood cancer. New England Journal ofMedicine, 355(15), 1572-1582. doi: 10.1056/NEJMsa060185

  47. Pierce, L., Hocking, M. C., Schwartz, L. A., Alderfer, M. A., Kazak, A. E., & Barakat,L. P. (2017). Caregiver distress and patient health-related quality of life:Psychosocial screening during pediatric cancer treatment. Psycho-Oncology,26(10), 1555-1561. doi: 10.1002/pon.4171

  48. Piñeros, M., Mery, L., Soerjomataram, I., Bray, F., & Steliarova-Foucher, E. (2021).Scaling Up the Surveillance of Childhood Cancer: A Global Roadmap. Journalof the National Cancer Institute, 113(1), 9-15. doi: 10.1093/jnci/djaa069

  49. Prussien, K. V., Murphy, L. K., Gerhardt, C. A., Vannatta, K., Bemis, H., Desjardins,L., … Compas, B. E. (2018). Longitudinal associations among maternaldepressive symptoms, child emotional caretaking, and anxious/depressedsymptoms in pediatric cancer. Journal of Family Psychology, 32(8), 1087-1096.doi: 10.1037/fam0000463

  50. Rebholz, C. E., Reulen, R. C., Toogood, A. A., Frobisher, C., Lancashire, E. R.,Winter, D. L., … Hawkins, M. M. (2011). Health care use of long-term survivorsof childhood cancer: the British Childhood Cancer Survivor Study. Journal ofClinical Oncology, 29(31), 4181-4188. doi: 10.1200/JCO.2011.36.5619

  51. Reyes-Lagunes, I., & García-Barragán, L. F. (2008). Procedimiento de validaciónpsicométrica culturalmente relevante: Un ejemplo. La Psicología Social enMéxico, 12(1), 625-630.

  52. Rivera-Luna, R., Zapata-Tarres, M., Shalkow-Klincovstein, J., Velasco-Hidalgo, L.,Olaya-Vargas, A., Finkelstein-Mizrahi, N., … Aguilar-Ortiz, M. R. (2017). Theburden of childhood cancer in Mexico: Implications for low- and middle-incomecountries. Pediatric Blood & Cancer, 64(6), e26366. doi: 10.1002/pbc.26366

  53. Rodríguez-Romo, L., Olaya Vargas, A., Gupta, S., Shalkow-Klincovstein, J., Vega-Vega, L., Reyes-Lopez., … Booth, C. M., (2018). Delivery of Pediatric CancerCare in Mexico: A National Survey. Journal of Global Oncology, 4, 1-12. doi:10.1200/JGO.17.00238

  54. Romito, F., Goldzweig, G., Cormio, C., Hagedoorn, M., & Andersen B. (2013).Informal Caregiving for cancer patients. Cancer, 119(Suppl 11), 2160-2169.doi: 10.1002/cncr.28057

  55. Seitz, D. C., Knaevelsrud, C., Duran, G., Waadt, S., & Goldbeck, L. (2014). Internetbasedpsychotherapy in young adult survivors of pediatric cancer: feasibility andparticipants’ satisfaction. Cyberpsychology, Behavior and Social Networking,17(9), 624-629. doi: 10.1089/cyber.2014.0066

  56. Shalkow, J. (2017). Cáncer en México, Situación Actual y Retos, (58). Retrievedfrom: https://www.paho.org/sites/default/files/Cancer-infantil-en-MEXICO.pdf

  57. Sharkey, C. M., Clawson, A. H., Mullins, L. L., Brinkman, T. M., Pui, C. H., Hudson,M. M., & Krull, K. R. (2019). The relationship of child executive functionsto parenting capacities in childhood acute lymphoblastic leukemia survivors.Pediatric Blood & Cancer, 66(8), e27761. doi: 10.1002/pbc.27761

  58. Sharpe, L., Turner, J., Fardell, J. E., Thewes, B., Smith, A. B., Gilchrist, J., … Butow,P. (2019). Psychological intervention (ConquerFear) for treating fear of cancerrecurrence: mediators and moderators of treatment efficacy. Journal of CancerSurvivorship, 13(5), 695-702. doi: 10.1007/s11764-019-00788-4

  59. Simard, S., & Savard, J. (2009) Fear of Cancer Recurrence Inventory: developmentand initial validation of a multidimensional measure of fear of cancer recurrence.Supportive Care Cancer, 17(3), 241‐251. doi: 10.1007/s00520-008-0444-y

  60. Simard, S., Thewes, B., Humphris, G., Dixon, M., Hayden, C., Mireskandari, S.,& Ozakinci, G. (2013). Fear of cancer recurrence in adult cancer survivors: Asystematic review of quantitative studies. Journal of Cancer Survivorship, 7(3),300-322. doi: 10.1007/s11764-013-0272-z

  61. Simonelli, L. E., Siegel, S. D., & Duffy, N. M. (2017). Fear of cancer recurrence: atheoretical review and its relevance for clinical presentation and management.Psycho-Oncology, 26(10), 1444-1454. doi: 10.1002/pon.4168

  62. Steliarova-Foucher, E., Colombet, M., Ries, L., Moreno, F., Dolya, A., Bray, F., …IICC-3 Contributors. (2017). International incidence of childhood cancer, 2001-10: a population-based registry study. The Lancet Oncology, 18(6), 719-731.doi: 10.1016/S1470-2045(17)30186-9

  63. Streiner, D. L., Norman, G. R., & Cairney, J. (2015). Health measurement scales: Apractical guide to their development and use (5th Ed). New York, NY: OxfordUniversity Press.

  64. Suh, E., Stratton, K. L., Leisenring, W. M., Nathan, P. C., Ford, J. S., Freyer, D. R., …Henderson, T. O. (2020). Late mortality and chronic health conditions in longtermsurvivors of early-adolescent and young adult cancers: A retrospectivecohort analysis from the Childhood Cancer Survivor Study. The LancetOncology, 21(3), 421-435. doi: 10.1016/S1470-2045(19)30800-9

  65. Wakefield, C. E., Sansom-Daly, U. M., McGill, B. C., McCarthy, M., Girgis, A.,Grootenhuis, M., … Cohn, R. J. (2015). Online parent-targeted cognitivebehaviouraltherapy intervention to improve quality of life in families of youngcancer survivors: study protocol for a randomized controlled trial. Trials, 16,153. doi: 10.1186/s13063-015-0681-6

  66. Wakefield, C., Sansom-Daly, U., McGill, B., Ellis, S., Doolan, E., Roberson, E., …Cohn, R. (2016). Acceptability and feasibility of an e-mental health interventionfor parents of childhood cancer survivors: Cascade. Supportive Care Cancer,24(6), 2685-2694. doi: 10.1007/s00520-016-3077-6

  67. Ward, E., DeSantis, C., Robbins, A., Kohler, B., & Jemal, A. (2014). Childhood andadolescent cancer statistics, 2014. CA: A Cancer Journal for Clinicians, 64(2),83-103. doi: 10.3322/caac.21219

  68. Wikman, A., Mattsson, E., von Essen, L., & Hovén, E. (2018). Prevalence andpredictors of symptoms of anxiety and depression, and comorbid symptoms ofdistress in parents of childhood cancer survivors and bereaved parents five yearsafter end of treatment or a child’s death. Acta Oncologica (Stockholm, Sweden),57(7), 950-957. doi: 10.1080/0284186X.2018.1445286

  69. Woodford, J., Wikman, A., Cernvall, M., Ljungman, G., Romppala, A., Grönqvist,H., & von Essen, L. (2018). Study protocol for a feasibility study of an internetadministered,guided, CBT-based, self-help intervention (ENGAGE) for parentsof children previously treated for cancer. BMJ Open, 8(6), e023708. doi:10.1136/bmjopen-2018-023708




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