2021, Number 5
Adult´s Nesidioblastosis. Case report
Language: Spanish
References: 13
Page: 858-862
PDF size: 255.78 Kb.
ABSTRACT
Adult nesidioblastosis is rare, defined as changes in the endocrine pancreas characterized by abnormal proliferation of pancreatic islet cells, diffusely affecting the gland, and causing persistent hyperinsulinemic hypoglycemia in the absence of an insulinoma. A case of a patient who is admitted to the internal medicine service at the “Dr. Gustavo Aldereguía Lima” Cienfuegos Hospital with a hypoglycemic syndrome for study. A 6-hour oral glucose tolerance test was performed with hypoglycemia (1.9mmol / L) at hour 5. 72-hour fasting test: with hypoglycemia at 2 hours with a paradoxical response to insulin, Glycemia and Insulinemia with the symptom. In the multislice abdominal computerized axial tomography, no lesion in the pancreas was evidenced. A distal pancreatectomy of ± 85% of the gland is performed with splenic preservation. The pathology anatomy confirmed nesidioblastosis. Nesidioblastosis in adults is a very rare entity, but it should be taken into account as a differential diagnosis of insulinomas in the absence of an evident lesion in conventional imaging studies.REFERENCES
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Flores Alvarado LJ, Sánchez Enríquez S, Zepeda Moreno A, Ramírez García SA, Bueno Topete MR, Ayub Ayala M, et al. Pancreatectomía proximal en nesidioblastosis. Gac. Méd. Méx [Internet]. 2005[citado 14/05/2020]; 141(2):[aprox. 3 p Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0016-38132005000200012&lng=es.