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ISSN 2305-7939 (Electronic)

2021, Number 3

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RCU 2021; 10 (3)

Urachal adenocarcinoma in adults

Suárez SSM, Rosero MMF, Álvarez RCG

Language: Spanish
References: 35
Page:
PDF size: 608.64 Kb.


ABSTRACT

Introduction: Urachal adenocarcinoma is a rare, aggressive malignant tumor first described in 1893 by Hue and Jaequin. It mainly affects male patients in their fifth and sixth decades of life. It represents 0.7% of all bladder cancers and 35% of all bladder adenocarcinomas. It is more frequent in men than in women, with a ratio of 5:1.
Objective: Determine the diagnosis and updated management of urachal adenocarcinoma in adults.
Methods: Initial long-standing studies published in the period 2010-2020 were consulted in the databases Medline, PubMed and Google Scholar. The full-text versions were obtained via open access to PubMed, HINARI and other sources.
Discussion: Urachal carcinomas emerge from the medial umbilical ligament stemming from the allantois, which extends from the dome of the bladder to the umbilicus. Obliteration of this extension before birth and its persistence as a fibrous cord constitute the urachus. Urachal cysts are formed when the urachus obliterates at the vesical and umbilical ends until a permeable portion remains between these ends which accumulates secretions acquiring a cystic appearance.
Conclusions: Malignant transformation of urachal cysts is rare, and no prophylactic treatment is recommended. Urachal carcinomas emerge from embryonic remains. The histology of the carcinoma should be similar to that of the enteric type, and other primary types should also be excluded before diagnosing a primary urachal carcinoma.


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