2023, Number 1
<< Back Next >>
Med Int Mex 2023; 39 (1)
COVID-19: Delphi analysis for the evaluation of the transition from pandemic to endemic in Mexico
Macías-Hernández A, Ruiz-Palacios G, Wong-Chew RM, López-Macías C, Galindo-Fraga A, Cornejo-Juárez P, Ruiz-Matus C, Becerra-Aquino A, López-Cervantes M, González-Roldán JF, Espinosa-Rosales F, Villaseñor-Ruiz I, Mascareñas-De los Santos A, Alcántar-Ramírez J, Otero-Mendoza F, García-Méndez J
Language: Spanish
References: 39
Page: 46-65
PDF size: 294.47 Kb.
ABSTRACT
Objective: To review and analyze the available information about the COVID-19
pandemic in Mexico and the determining factors for its transition to an endemic phase.
Material and Method: Prospective study based on the Delphi Method with
the participation of a panel made up by specialists in infectious diseases, immunology,
internal medicine, pulmonology, pediatrics and public health.
Results: 2270 bibliographic sources were identified; after excluding those that offered
repetitive information, 454 were included in the final analysis. The main factors that
obstruct the transition from a COVID-19 pandemic to an endemic one were defined as
the high capacity of SARS-CoV-2 to mutate (since the efficacy of anti-COVID-19 vaccines
depends to a large extent on the genetic presentations of the virus) and the high
prevalence in the country of comorbidities that make the population more vulnerable
against the disease. Strengthening primary care and promoting a culture of surveillance
and prevention are essential.
Conclusiones: It was concluded, by consensus, that there are factors that obstruct
the passage of the COVID-19 pandemic to an endemic phase, including the intrinsic
nature of disease control and the unpredictability of virus mutations.
REFERENCES
Johns Hopkins Coronavirus Resource Center. Coronavirusglobal map. Dirección URL: (Consulta: noviembre 2022).
Gobierno de México, Secretaría de Salud, Dirección Generalde Epidemiología. Informe integral de COVID-19 en México.Número 09-2022, 03 de agosto de 2022. Dirección URL: (Consulta:noviembre 2022).
Sánchez-Herrera K, Lugo-Maldonado M, Huerta-Olvera SG.“Retos e implicaciones en el Sistema de Salud por la pandemiade COVID-19.” En: Medel-Palma C, Rodríguez-NavaA, Jiménez-Bustos GR, Martínez-Rojas Rustrián R. Méxicoante el COVID-19: acciones y retos. Cámara de Diputados,Universidad Autónoma Metropolitana, México, 2020; cap.12 (pp. 127-38).
Al‑Tawfq JA, Dinh‑Toi C, Van‑Thuan H, Memish ZA. Frompandemicity to endemicity: the journey of SARS‑CoV‑2. JEpidemiol Global Health 2022; 12: 147-9. DOI: https://doi.org/10.1007/s44197-022-00046-4.
Jamil B. Is COVID-19 pandemic really coming to an end? JPak Soc Intern Med 2022; 3 (1): 1-2.
Byers P. SARS-CoV-2 pandemic to endemic: when will weknow and what will it look like? J MSMA 2022; 63 (6): 174-6.
Septiani-Pontoh R, Toharudin T, Nurani-Ruchjana B, etal. Jakarta pandemic to endemic transition: forecastingCOVID-19 using NNAR and LSTM. Appl Sci 2022; 12 (5771).DOI: https://doi.org/10.3390/app12125771.
Wilson C. What covid-19 becoming ‘endemic’ really means.New Scientist, 22 January 2022: 14.
Suárez V, Suárez-Quezada M, Oros-Ruiz S, Ronquillo DeJesús E. Epidemiología de COVID-19 en México: del 27 defebrero al 30 de abril de 2020. Rev Clin Esp 2020; 220 (8):463-71. DOI: https://doi.org/10.1016/j.rce.2020.05.007.
Orellana-Centeno JE, Guerrero Sotelo RN. El proceso devacunación en México. Rev ADM 2021;78(5):270-4. doi:10.35366/102034.
Knaul F, et al; Group from the Observatory for the Containmentof COVID-19 in the Americas. Not far enough: publichealth policies to combat COVID-19 in Mexico’s states. PLoSONE 2021; 16 (6). DOI: https://doi.org/10.1371/journal.pone.0251722.
Ortiz-Ibarra FJ, et al. COVID-19: prevención, diagnóstico ytratamiento; recomendaciones de un grupo multidisciplinario.Med Int Méx 2022; 38 (2): 288-321. DOI: https://doi.or g/10.24245/mim.v38i2.7493.
Conexión Cinvestav. Las vacunas contra COVID-19 y susdistintos mecanismos de acción; boletín de prensa del08 de febrero de 2022. Dirección URL: (Consulta:noviembre 2022).
Gutiérrez-López JI, Rodríguez-Reyna R, Garcés-EspinosaJV, Labrada-Rosabal KI. Vacunación con Abdala, actitudese impacto psicológico en el personal de salud de Niquero.Multimed 2021; (25) 6: e2457.
Centro para el Control Estatal de Medicamentos, Equiposy Dispositivos Médicos (CECMED). Abdala, vacuna anti-COVID-19 de subunidad proteica. No. de Autorización deUso en Emergencia: Resolución No. 113/21; fecha deemisión de la autorización: 9 de julio de 2021.
Comisión Federal para la Protección contra RiesgosSanitarios (Cofepris). Cofepris emite autorización parauso de emergencia de vacuna Abdala. Comunicado ala población No. 43/2021, 29 de diciembre de 2021.Dirección URL: (Consulta: noviembre 2022).
García-Osorno ZR, et al. Vacunas contra la COVID-19. ActaMed Grupo Ángeles 2021; 19 (3): 429-44. DOI: https://dx.doi.org/10.35366/101742.
Conecta, Tecnológico de Monterrey. Vacunas contra COVID:características y diferencias. Dirección URL: (Consulta:noviembre 2022).
Sadarangani M, Marchant A, Kollmann TR. Immunologicalmechanisms of vaccine-induced protection against COVID-19 in humans. Nat Rev Immunol 2021; 21: 475-84. DOI:https://doi.org/10.1038/s41577-021-00578-z.
Gutiérrez BD, et al. Efectos a largo plazo de la COVID-19:una revisión de la literatura. Acta Med Grupo Ángeles 2021;19 (3): 421-8. DOI: https://dx.doi.org/10.35366/101741.
Palacio-Lapuente J; Sociedad Española de Medicina deFamilia y Comunitaria (semFYC). Covid-19 y AtenciónPrimaria: las oleadas que vienen: altas hospitalarias,pacientes críticos sin tratamiento hospitalario y atencióndemorada que pasa a ser indemorable o urgente. DirecciónURL: (Consulta:noviembre 2022).
Lazarus R, Baos S, Cappel-Porter H, Carson-Stevens A, etal; ComfluCOV Trial Group. Safety and immunogenicity ofconcomitant administration of COVID-19 vaccines (ChAdOx1or BNT162b2) with seasonal influenza vaccines inadults in the UK (ComFluCOV): a multicentre, randomised,controlled, phase 4 trial. Lancet 2021; 398: 2277-87. DOI:https://doi.org/10.1016/S0140-6736(21)02329-1.
Izikson R, Brune D, Bolduc JS, Bourron P, et al. Safety andimmunogenicity of a high-dose quadrivalent influenzavaccine administered concomitantly with a third dose ofthe mRNA-1273 SARS-CoV-2 vaccine in adults aged ≥65years: a phase 2, randomised, open-label study. LancetRespir Med 2022; 10 (4): 392-402. doi: 10.1016/S2213-2600(21)00557-9.
Organización Mundial de la Salud. Inmunidad colectiva,confinamientos y COVID-19: preguntas y respuestas; 31de diciembre de 2020. Dirección URL: . (Consulta: noviembre 2022).
Meng H, Mao J, Ye Q. Strategies and safety considerationsof booster vaccination in COVID-19. Bosn J Basic Med Sci2022; 22 (3): 366-73. doi: 10.17305/bjbms.2021.7082.
Sekalala S, et al. An intersectional human rights approach toprioritising access to COVID-19 vaccines. BMJ Glob Health2021; 6 (2). doi: 10.1136/bmjgh-2020-004462.
Grupo Técnico Asesor de Vacunación Covid-19. Priorizacióninicial y consecutiva para la vacunación contra SARS-CoV-2en la población mexicana: recomendaciones preliminares.Salud Pública Méx 2021; 63: 286-307. doi: https://doi.org/10.21149/12399.
Smith MJ. Why we should not ‘just use age’ for COVID-19vaccine prioritisation. J Med Ethics 2022; 48 (8): 538-541.doi: 10.1136/medethics-2021-107443.
Russo AG, Decarli A, Valsecchi MG. Strategy to identifypriority groups for COVID-19 vaccination: a populationbased cohort study. Vaccine 2021; 39 (18): 2517-25. doi:10.1016/j.vaccine.2021.03.076.
Faundes V, Pardo R, Cammarata-Scalisi F, Alarcón P, Lay-Son G,San Martín E. Consenso de la Rama de Genética de la SociedadChilena de Pediatría sobre priorización de personas conSíndrome de Down y otras condiciones poco frecuentes en laCampaña de Vacunación COVID-19. Andes Pediatr 2021; 92(2): 309-15. doi: 10.32641/andespediatr.v92i2.3716.
Lavine JS, Bjornstad ON, Antia R. Immunological characteristicsgovern the transition of COVID-19 to endemicity.Science 2021; 371 (6530): 741-5. doi: 10.1126/science.abe6522.
Watkinson RE, Williams R, Gillibrand S, Sanders S, et al.Ethnic inequalities in COVID-19 vaccine uptake and comparisonto seasonal influenza vaccine uptake in GreaterManchester, UK: a cohort study. PLoS Med 2022; 19 (3).doi: 10.1371/journal.pmed.1003932.
Yang J, Zheng W, Shi H, Yan X, et al. Who should be prioritizedfor COVID-19 vaccination in China? A descriptivestudy. BMC Med 2021; 19 (1): 45. doi: 10.1186/s12916-021-01923-8.
Jain V, Schwarz L, Lorgelly P. A rapid review of COVID-19 vaccineprioritization in the U.S.: alignment between federalguidance and state practice. Int J Environ Res Public Health2021; 18 (7). doi: 10.3390/ijerph18073483.
Hughes K, Gogineni V, Lewis C, Deshpande A. Considerationsfor fair prioritization of COVID-19 vaccine and its mandateamong healthcare personnel. Curr Med Res Opinion2021; 37 (6): 907-9. doi: 10.1080/03007995.2021.1908245.
Nicholas W, Sood N, Lam C, Kotha R; et al. Did prioritizingessential workers help to achieve racial/ethnic equity inearly COVID-19 vaccine distribution? The LA pandemicsurveillance cohort study. Am J Ind Med 2022;65(4):231-41.doi; 10.1002/ajim.23335.
Luyten J, Tubeuf S, Kessels R. Rationing of a scarce lifesavingresource: public preferences for prioritizing COVID-19 vaccination. Health Econ 2022; 31 (2): 342-62. doi:10.1002/hec.4450.
Lazarus JV, et al; COVID-19 Consensus Statement Panel.A multinational Delphi consensus to end the COVID-19public health threat. Nature 2022; 611 (7935): 332-345.doi: 10.1038/s41586-022-05398-2.
World Health Organization. Ten Threats to global health in2019. Dirección URL: (Consulta:noviembre 2022).