2021, Number 3
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Rev Cub Med Int Emerg 2021; 20 (3)
Plasmodium falciparum malaria as a cause of cerebral infarction in children
Céspedes RHR, Muando CVI
Language: Spanish
References: 21
Page: 1-10
PDF size: 249.16 Kb.
ABSTRACT
Introduction: Cerebral malaria, caused by Plasmodium falciparum, is the most serious neurological complication of malaria. In addition to diffuse brain damage, focal ischemic-type lesions may appear. The obstruction of cerebral blood flow and the inflammatory response constitute the main mechanisms for ischemia and occlusive cerebral infarction.
Objective: To describe the diagnosis, treatment and evolution of two children with cerebral infarction secondary to malaria by Plasmodium falciparum.
Case report: We report two patients admitted to the Pediatric Intensive Care Unit, Maputo Central Hospital, Mozambique, diagnosed with cerebral malaria and who, during the course of the disease, had seizures and signs of neurological targeting. The computed tomography scan showed cerebral infarction. Both patients were treated according to the treatment protocol for cerebral malaria associated with antiplatelet medication and vasodilators. They were discharged from the institution recovered, with neurological sequelae.
Conclusions: In patients with cerebral malaria, the appearance of focal neurological manifestations is suspicion of the presence of a symptomatic ischemic infarction. Therefore, imaging studies that support the clinical diagnosis should be prescribed.
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