medigraphic.com
ISSN 1727-897X (Electronic)

2021, Number 3

<< Back Next >>

Medisur 2021; 19 (3)

Patients with dengue clinical-epidemiological behavior. Comparative study of two case series

García GCA, Sánchez SS, Pantoja FD, Rodríguez MO, Navarro BAL, García MC

Language: Spanish
References: 20
Page: 421-428
PDF size: 268.23 Kb.


ABSTRACT

Background: The disease caused by the dengue virus constitutes a serious health problem for tropical countries. The last decade has seen the re-emergence of this entity in Cuba, with evident changes in its clinical behavior.v Objective: to compare the clinical-epidemiological behavior between two series of cases of patients with dengue confirmed diagnosis, in different periods of time.
Methods: a descriptive, comparative study that included two series of cases of hospitalized patients with dengue confirmed diagnosis: series A, sample of 83 patients seen in 2017; and series B, sample of 327 seen in 2018. Variables such as: age, signs and symptoms, clinical findings, alarm signs, severe forms, and indicators of quality of care in dengue patients were analyzed.
Results: in general, the acute febrile syndrome predominated, although other signs and symptoms such as asthenia, anorexia, rash and retro-ocular pain, manifested a higher incidence in series B. In both groups the most frequent paraclinical finding was lymphocytosis. In series B, the quality standards for the care of patients with dengue were more affected; as well as it also presented a higher rate of alarm signs, serious forms and complications.
Conclusions: Although the study analyzed series of patients in two consecutive periods, the more complex behavior was evident in the second, due to the higher incidence of symptoms and less favorable figures for the quality standards established for the disease.


REFERENCES

  1. Espinal MA, Andrus JK, Jauregui B, Hull S, Morens DM, Santos JI, et al. Emerging and Reemerging. Aedes-Transmitted Arbovirus Infections in the Region of the Americas: Implications for Health Policy. Am J Public Health. 2019;109(3):387-92

  2. Messina JP, Brady OJ, Golding N, Kraemer MUG, Wint GRW, Ray SE, et al. The current and future global distribution and population at risk of dengue. Nat Microbiol. 2019;4(9):1508-15

  3. Ryan SJ, Carlson CJ, Mordecai EA, Johnson LR. Global expansion and redistribution of Aedes-borne virus transmission risk with climate change. PLoS Negl Trop Dis. 2019;13(3):e0007213

  4. Organización Panamericana de la Salud. Dengue: Guías para la atención de enfermos en la Región de las Américas [Internet]. Washington DC: OPS; 2016 [citado 8 Oct 2020]. Disponible en: https://www.paho.org/hq/dmdocuments/2012/Guias-atencion-enfermos-Americas-2010-esp.pdf

  5. Organización Panamericana de la Salud. Instrumento para el diagnóstico y la atención a pacientes con sospecha de arbovirosis [Internet]. Washington DC: OPS; 2016 [citado 8 Oct 2020]. Disponible en: https://iris.paho.org/bitstream/handle/10665.2/31448/9789275319369_spa.pdf?sequence=5&isAllowed=y

  6. Organización Panamericana de la Salud OPS/OMS. Guía de Atención Clínica Integral del Paciente con Dengue [Internet]. Bogotá: OPS; 2010 [citado 8 Oct 2020]. Disponible en: http://manizalessalud.net/wp-content/uploads/2019/03/guia_para_atencion.pdf

  7. Espinosa AD. Memorias de la atención a enfermos durante la epidemia de dengue de 1981. Medisur [revista en Internet]. 2014 [citado 8 Oct 2020];12(4):[aprox. 20p]. Disponible en: http://medisur.sld.cu/index.php/medisur/article/view/2839/1522

  8. Espinosa Brito AD. Fiebre hemorrágica dengue. Estudio clínico en pacientes adultos hospitalizados. Medisur [revista en Internet]. 2014 [citado 8 Oct 2020];12(4):[aprox. 10p]. Disponible en: http://medisur.sld.cu/index.php/medisur/article/view/2836/1521

  9. García C, Rodríguez O, Fernández C, Rodríguez M. Evolución clínico-epidemiológica de pacientes con diagnóstico de dengue. Enero-junio 2017. Medisur [revista en Internet]. 2019 [citado 8 Oct 2020];17(6):[aprox. 8p]. Disponible en: http://medisur.sld.cu/index.php/medisur/article/view/4200/2999

  10. García C, Rodríguez M, García V, Peña A, Ramírez M, Rodríguez O. Organización de los servicios hospitalarios a propósito de un brote de arbovirosis. Cienfuegos 2018. Medisur [revista en Internet]. 2019 [citado 8 Oct 2020];17(4):[aprox. 5p]. Disponible en: http://medisur.sld.cu/index.php/medisur/article/view/4246/2929

  11. Rodríguez D, Delgado H, Valladares M, Rojas N, Díaz A. Repercusión de eventos de arbovirosis sobre indicadores hospitalarios seleccionados, Hospital Pediátrico de Cienfuegos (2014-2018). Medisur [revista en Internet]. 2020 [citado 8 Oct 2020];18(2):[aprox. 7p]. Disponible en: http://medisur.sld.cu/index.php/medisur/article/view/4480/3071

  12. Valdés LE. Aportes al conocimiento del dengue y dengue hemorrágico en Santiago de Cuba [Tesis]. La Habana: Instituto de Medicina Tropical Pedro Kourí; 2016 [citado 8 Oct 2020]. Disponible en: http://tesis.sld.cu/index.php?P=DownloadFile&Id=708

  13. López R. Dengue serotipo 3 y embarazo: aspectos clínicos y epidemiológicos [Tesis]. Santiago de Cuba: Universidad de Ciencias Médicas de Santiago de Cuba; 2017 [citado 8 Oct 2020]. Disponible en: http://tesis.sld.cu/index.php?P=DownloadFile&Id=709

  14. Yacoub S, Farrar Y. Dengue. En: Farrar J, Hotez PJ, Junghanss T, Kang G, Lalloo D, White NJ, editores. Manson's Tropical Infectious Diseases. 23rd. ed. Oxford: WB Saunders; 2014. p. 162-70

  15. Guzmán MG, Fuentes O, Martínez E, Pérez AB. Dengue. En: Quah SR, editores. International Encyclopedia of Public Health. 2nd. ed. Oxford: Academic Press; 2017 [citado 8 Oct 2020]. p. 233-57. Disponible en: https://www.sciencedirect.com/science/article/pii/B978012803678500103X?via=ihub

  16. Pardo D, Ojeda B, Alonso A. Dinámica de la respuesta inmune en la infección por virus del dengue. Medisur [revista en Internet]. 2018 [citado Oct 8];16(1):[aprox. 8p]. Disponible en: http://medisur.sld.cu/index.php/medisur/article/view/3456/3071

  17. Beita J, Salazar N, Valverde M. Patogénesis de la enfermedad por virus del dengue. Revisión de la literatura. Rev Clín Esc Med [revista en Internet]. 2016 [citado 8 Oct 2020];6(2):[aprox. 13p]. Disponible en: https://revistas.ucr.ac.cr/index.php/clinica/article/view/24335/24439

  18. Díaz FA, Villar LA, Martínez RA. Predictors of spontaneous bleeding in patients with acute febrile síndrome from a dengue endemic area. J Clin Virol. 2010;49(1):11-5

  19. Ang LW, Thein TL, Ng Y, Boudville IC, Chia PY, Lee VJM, et al. A 15-year review of dengue hospitalizations in Singapore: Reducing admissions without adverse consequences, 2003 to 2017. PLoS Negl Trop Dis. 2019;13(5):e0007389

  20. Vuong NL, Quyen NTH, Tien NTH, Tuan NM, Kien DTH, Lam PK, et al. Higher plasma viremia in the febrile phase is associated with adverse dengue outcomes irrespective of infecting serotype or host immune status: an analysis of 5642 Vietnamese cases. Clin Infect Dis [revista en Internet]. 2020 [citado 8 Oct 2020];(2020):[aprox. 40p]. Disponible en: https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa1840/6041872




2020     |     www.medigraphic.com