2021, Number 3-4
Improving Ketosis-Prone Type 2 Diabetes Diagnosis in Africa
Language: English
References: 7
Page: 61-62
PDF size: 137.58 Kb.
Text Extraction
Diabetes mellitus (DM) is a serious health problem with high— and increasing—prevalence and incidence around the world. Africa, with a considerable communicable disease burden, is not exempt and is facing greater DM risk due to rapid demographic, sociocultural, economic and nutritional changes. According to the International Diabetes Federation, Africa will experience the largest jump in DM prevalence (143%) of all regions over the next 25 years.As a member of the Cuban medical team working in Luanda, Angola, I’ve repeatedly seen male patients presenting with newonset diabetic ketoacidosis (DKA) without evident precipitating cause. Medical records show these patients are between 40 and 50 years old; during ambulatory follow-up, they sometimes maintain good metabolic control despite having discontinued insulin therapy due to dramatic decline in glycemia. These clinical findings suggest the presence of ketosis-prone type 2 diabetes (KPD). Unfortunately, this variant of type 2 diabetes is often not considered during diagnosis and can lead to misclassification and incorrect treatment protocols.
REFERENCES
Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, et al.Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation DiabetesAtlas, 9th edition. Diabetes Res Clin Pract. 2019 Nov;157:107843. DOI:10.1016/j.diabres.2019.107843. Epub 2019 Sep 10.
Atun R, Davies JI, Gale EAM, Bärnighausen T, Beran D, Pascal KengneA, et al. Diabetes in sub-Saharan Africa: from clinical care to health policy.Lancet Diabetes Endocrinol Commission [Internet]. 2017 Jul [cited 20 20 Nov5];5(8):622–67. Available at: https://www.thelancet.com/journals/landia/article/PIIS2213-8587(17)30181-X/fulltext