2021, Number 3
Citología exfoliativa en el diagnóstico precoz del cáncer bucal
Language: Spanish
References: 15
Page: 428-438
PDF size: 588.36 Kb.
ABSTRACT
Introduction: the early diagnosis is a key factor in the management of an oral cancer, so, it is very important the implementation of simple, not harmful and liable diagnosis method. In this sense, the interest in oral cytology has increased for diagnosing and monitoring.Objetive: to determine the usefulness of exfoliative cytology in the brushiness as a method for the early diagnosis in oral cancer.
Methos: a descriptive, cross-sectional, quanti-qualitative and double blind study was made in the Maxillofacial Surgery service from Arnaldo Milián Castro Hospital, between March 2016 and October 2017. The sample was set by 33 patients who had oral lesions with suspicion of malignancy or premalignancy.
Results: there was a predomination in the masculine sex (63,6%) and those whose ages were between 60 and 69 years (33,3%). The sample with dental brush was painless for the 45,5% of patients; while 54,5% of them referred slight discomfort. There was a concordance of 0,89 according to Kappa index between the presence of neoplastic cells that were detected trough cytology and biopsy with a high diagnostic value of test, with positive predictive value (0,95) and negative predictive value (0,93). According to the grade of differentiation of the malignant tumor, the concordance between both methods was slight (0,094).
Conclusions: the cytology was a useful method for the diagnosis of oral cancer, that showed a coincidence with the histopathological diagnosis in predomination way.
REFERENCES
Acha A, Ruesga MT, Rodríguez MJ, Martínez de Pancorbo MA, Aguirre JM. Aplicaciones de la citologia oral por raspado (exfoliativa) en el cáncer y precáncer oral. Med Oral Patol Oral Cir Bucal [Internet]. 2005 Mar-Apr [citado 20/10/2018];10(2):95-102. Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1698-44472005000200001
Diniz Freitas M, García García A, Crespo Abelleira A, Martins Carneiro JL, Gándara Rey JM. Aplicaciones de la citología exfoliativa en el diagnóstico del cáncer oral. Med Oral Patol Oral Cir Bucal (Ed.impr.) [Internet]. 2004 Oct [citado 20/10/2018];9(4):355-361. Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1698-44472004000400014
García-Roco Pérez O, Arredondo López M, Álvarez Navarro MC. Citología exfoliativa en el diagnóstico precoz de lesiones oncológicas bucales. Rev Cubana Estomatol [Internet]. 2002 May-Ago [citado 20/10/2018];39(2):89-100. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75072002000200002
Estrada Pereira GA, Márquez Filiu M, González Heredia E, Nápoles Pruna MM, Ramón Jiménez R. Infección por virus del papiloma humano en la cavidad bucal. MEDISAN [Internet]. 2015 Mar [citado 20/10/2018];19(3):300-306. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30192015000300002
Diéguez Pérez AR, Correa Rodríguez R, Fonseca del Rey S, Diéguez Pérez LB, Sardiña Hernández Y, Cedeño Gomez Y. Caracterización del cáncer bucal en la Isla de Juventud. 2007 - 2018. Rev Med Isla Juventud [Internet]. 2019 [citado 03/03/2021];20(1):[aprox. 15 p.]. Disponible en: http://www.remij.sld.cu/index.php/remij/article/view/216/420
Rodríguez Martín O, Betancourt Valladares M, García Ranero AB, Giance Paz L. Pronóstico de incidencia y mortalidad del cáncer bucal en la provincia Ciego de Ávila. Rev Cubana Estomatol [Internet]. 2017 Jul-Sep [citado 20/10/2018];54(3):[aprox. 11 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75072017000300005