2022, Number 6
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Med Int Mex 2022; 38 (6)
Triad of endocarditis, spondylodiscitis and epidural abscess due to S. intermedius
Roig-Marín N, Roig-Rico P, Calbo-Maiques J, Seguí-Ripoll JM
Language: Spanish
References: 13
Page: 1296-1299
PDF size: 228.14 Kb.
ABSTRACT
Background: Streptococcus intermedius together with
S. anginosus and
S. constellatus
form the group
S. anginosus (previously called
S. milleri), anteriorly considered a type of
S. viridans. Sometimes they can cause infections with a tendency to abscess at the liver
and brain, but it is rare to find it as an etiologic agent of endocarditis, spondylodiscitis
and epidural abscess. Therefore, the coexistence of the three locations is exceptional.
Clinical cases: A 72-year-old male patient was hospitalized because of decreased
level of consciousness with aphasia. The patient reported low back pain with mechanical
characteristics. During the first day, he presented a feverish peak and blood
cultures were extracted in which
Streptococcus intermedius grew. On lumbar spine
MRI, spondylodiscitis was reported on L4-L5 and abscess in the anterior epidural space
at the L5 level. A transesophageal echocardiogram was also performed, which showed
two warts in the aortic and mitral valves. It was decided to give surgical treatment with
valve replacement with a metallic mitral prosthesis. The epidural abscess was cured
after antibiotic treatment.
Conclusions: In a patient with
S. intermedius endocarditis, the aggressiveness of
the germ and the tendency to form abscesses in different locations must be taken into
account. The presence of low back pain forces to rule out spondylodiscitis and an
epidural abscess.
REFERENCES
Tran MP, Caldwell-McMillan M, Khalife W, Young VB.Streptococcus intermedius causing infective endocarditisand abscesses: a report of three cases and review of theliterature. BMC Infect Dis 2008; 8: 154. doi:10.1186/1471- 2334-8-154.
Le Moal G, Roblot F, Paccalin M, et al. Clinical and laboratorycharacteristics of infective endocarditis whenassociated with spondylodiscitis. Eur J Clin Microbiol InfectDis 2002; 21 (9): 671-5. doi:10.1007/s10096-002-0798-x.
Calderaro D, Gualandro DM, Yu PC, Marques AC, Puig LB,Caramelli B. Spondylodiscitis and infectious endocarditis: around-trip to be considered. Braz J Infect Dis 2008; 12 (6):544-5. doi:10.1590/s1413-86702008000600021.
Salem A, Azeez S, Stirrup J, Lawrence D, Ruparelia N. Streptococcusintermedius masquerading as fungal infectiveendocarditis. Br J Hosp Med (Lond) 2019; 80 (11): 674-5.doi:10.12968/hmed.2019.80.11.674.
Rashid RM, Salah W, Parada JP. Streptococcus milleri aorticvalve endocarditis and hepatic abscess. J Med Microbiol2007; 56 (Pt 2): 280-2. doi:10.1099/jmm.0.46781-0.
Lampen R, Bearman G. Epidural abscess caused by Streptococcusmilleri in a pregnant woman. BMC Infect Dis 2005;5: 100. doi:10.1186/1471-2334-5-100.
Bert F, Bariou-Lancelin M, Lambert-Zechovsky N. Clinicalsignificance of bacteremia involving the “Streptococcusmilleri” group: 51 cases and review. Clin Infect Dis 1998;27 (2): 385-387. doi:10.1086/514658.
Magallanes A, Videgaray F, Manjarrez E, Skromne E, GómezMM, Cisneros D. 0968 Absceso epidural de médula espinalpor Streptococcus intermedius (Streptococcus milleri) enun paciente previamente sano. XL Congreso Nacional deMedicina Interna. Resúmenes. Infectología. Med Int Méx2017; 33: S346.
Heckmann JG, Pauli SU. Epidural abscess after dentalextraction. Age Ageing 2015; 44 (5): 901. doi:10.1093/ageing/afv094.
Ramhmdani S, Bydon A. Streptococcus intermedius: anunusual cause of spinal epidural abscess. J Spine Surg 2017;3 (2): 243-249. doi:10.21037/jss.2017.05.04.
Petti CA, Stratton CW. Streptococcus anginosus group. In:Bennett JE, Dolin R, Blaser MJ, editors. Mandell, Douglas andBennett’s. Eight edition. Principles and Practice of InfectiousDiseases. Philadelphia: Elsevier Saunders, 2015: 2362-2365.
Bantar C, Fernández Canigia L, Relloso S, Lanza A, BianchiniH, Smayevsky J. Species belonging to the “Streptococcusmilleri” group: antimicrobial susceptibility and comparativeprevalence in significant clinical specimens. J Clin Microbiol1996; 34: 2020-2. doi: 10.1128/jcm.34.8.2020-2022.1996.
Crespo-Valadés E, Barberá-Farré JR, Ruiz de Gauna-MartínE, Cabra-Dueñas J. Bacteriemia, endocarditis y abscesocervical por Streptococcus intermedius. An Med Interna(Madrid) 2003; 20 (11): 55-6.