2021, Number 2
Polypharmacy and pharmacological adherence in adults at ''Louis Pasteur'' Teaching Polyclinic
Language: Spanish
References: 18
Page: 1-9
PDF size: 215.72 Kb.
ABSTRACT
Introduction: polypharmacy constitutes a phenomenon with significant consequences, therefore the importance of recognizing its risk factors.Objective: to determine the factors associated with polypharmacy and its impact on therapeutic adherence in adults.
Methods: observational, analytical and cross-sectional study in patients from Number 10 Family Doctor’s Office at “Louis Pasteur” Teaching Polyclinic, between January and March 2021. The population comprised 222 patients, and the sample included 106 patients chosen by simple random sampling. Descriptive and inferential statistics was applied.
Results: predominance of patients from 70 years old or older (42,27 %) and average poly-medication (42,27 %). Self-medication was found in 77,4 % of patients. A total of 58,49 % of the population attended two or more inter-consultations and 33,01 % presented adverse drug reactions. Hypertension (77,32 %) and diabetes (27,84 %) predominated as comorbidities. Adherence was higher in ocular diseases and lower in oncologic diseases (100 %). An association was identified between major polypharmacy and unemployment (OR:3,37; CI:1,05-10,74; p=0,033), two or more comorbidities (OR:1,52; CI:1,28-1,8; p<0,01), adverse reactions (OR:5,17; CI:1,96-13,6; p<0,01), and two or more inter-consultations (OR:25,36; CI:3,27-196,68; p<0,01).
Conclusions: polypharmacy was frequent mainly in older adults with hypertension and diabetes mellitus as underlying diseases. Unemployment, the presence of two or more comorbidities, two or more inter-consultations and the occurrence of adverse reactions favored polypharmacy.
REFERENCES
Hernández Ugalde F, Álvarez Escobar MD, Martínez Leyva G, Junco Sánchez VL, Valdés Gasmury I, Hidalgo Ruiz M. Polifarmacia en el anciano. Retos y soluciones. Rev medica electronica [Internet]. 2018 [citado 21/01/2021]; 40(6): [aprox. -2070 p.]. Disponible en: http://www.revmedicaelectronica.sld.cu/index.php/rme/article/view/2640
Sanabria C, Guzmán F. Adherencia farmacoterapéutica en pacientes geriátricos del Hospital Santa Bárbara in Sucre - Bolivia. Rev. Cien. Tec. In.[Internet]. 2018 [citado 21/01/2021]; 16(17):983-990. Disponible en: http://www.scielo.org.bo/scielo.php?script=sci_arttext&pid=S222587872018000100003&lng=es&nrm=iso
Da Silva Córralo V, Marconatto Binotto V, Bohnen L, Gonzaga dos Santos GA, De-SáClodoaldo A. Factores asociados con la polifarmacia en los ancianos diabéticos. Rev. Salud pública [Internet]. 2018 [citado 25/01/2021]; 20(3):366-372. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S012400642018000300366&lng=en
Ramírez Pérez A, Cisneros Nápoles Y, Castellanos González M, Ramírez Pérez J, Bórrelo Zayas J. Polifarmacia y complejidad farmacoterapéutica en pacientes de hogares de ancianos en Cienfuegos. Una evaluación desde la comunidad. Rev. Haban cienc méd. [Internet]. 2021 [citado 24/01/2021]; 20(3):e3646. Disponible en: http://www.revhabanera.sld.cu/index.php/rhab/article/view/3643
Gort Hernández M, Guzmán Carballo NM, Mesa Trujillo D, Miranda Jerez PA, Espinosa Ferro Y. Caracterización del consumo de medicamentos en el adulto mayor. Rev Cubana Med Gen Integr [Internet]. 2019 [citado 27/01/2021] ; 35(4):e970. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21252019000400010&lng=es
Martínez Arroyo JL, Gómez García A, Sauceda Martínez D. Prevalencia de la polifarmacia y la prescripción de medicamentos inapropiados en el adulto mayor hospitalizado por enfermedades cardiovasculares. Gac. Méd. De Méx. [Internet]. 2014 [citado 29/01/2021]; 150(1):29-38. Disponible en: https://www.medigraphic.com/pdfs/gaceta/gm-2014/gms141d
Ramírez PA, Furones Mourelle J, Cedeño Ramos A. Deprescripción en el anciano polimedicado. Una mirada reflexiva en el contexto cubano. Rev haban cienc méd [Internet]. 2020 [citado 27/01/2021] ; 19(3):e3416. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1729519X2020000300012&lng=es.
García-Orihuela M, Suárez-Conejero A, Otero-Morales J, Alfonso-Orta I, Caballero-Conesa G. Génesis de la polifarmacia y las prescripciones inapropiadas STOPP en ancianos. Anal. de la Acad. De Cienc. De Cuba [Internet]. 2020 [citado 29/01/2021]; 10(3): [aprox. 0 p.]. Disponible en: http://www.revistaccuba.cu/index.php/revacc/article/view/925