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2022, Number 2

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Arch Inv Mat Inf 2022; 13 (2)

Oral medium chain triglycerides in premature infants and their relationship with brachial circumference

Rodríguez-Balderrama I, Galindo-Aguilar OU, Cisneros-Hernández J, Nieto-Sanjuanero A, Medina-de CAY, Morales-Rodríguez IB, Ochoa-Correa ÉC

Language: Spanish
References: 12
Page: 79-83
PDF size: 157.54 Kb.


ABSTRACT

Introduction: poor weight gain in the preterm infant is a cause of prolonged hospital stay. Enteral medium chain triglyceride (MCT-oil) is a strategy for gaining body fat stores and muscle mass. Objective: to investigate the role of MCT-oil as an enteral supplement by assessing brachial circumference and the brachial circumference/head circumference index (BC/HC). Material and methods: observational, comparative, case-control study. The first group is with preterm infants supplemented with MCT-oil. The control group, preterm infants without MCT-oil supplementation. Dose of 2 mL/kg/day in eight intakes administered directly into the mouth coinciding with milk intake. Results: at discharge, the MCT group presented higher arm circumference than the control group (7.2 ± 0.77 vs 6.4 ± 0.46) p < 0.05. At four weeks of outpatient follow-up the MCT group had greater brachial circumference than the control group (10.4 ± 1.4 vs 8.6 ± 1.7) p < 0.05. Comparing the BC/HC index at discharge the MCT group had higher BC/HC index than the control group (0.2314 ± 0.26 vs 0.2108 ± 0.14) p < 0.001, but at four weeks there was no significant difference (p = 0.080). Conclusions: the use of MCT-oil as a preterm supplement is good strategy for gaining body fat stores and muscle mass.


REFERENCES

  1. Black RE, Cousens S, Johnson HL, Lawn JE, Rudan I, Bassani DG et al. Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet. 2010; 375 (9730): 1969-1987.

  2. Rodriguez-Balderrama I. Neonatal mortality, prematurity, and late-onset sepsis: A global public health problem. Medicina Universitaria. 2018; 20: 107-109.

  3. Keunen K, van Elburg RM, van Bel F, Benders MJ. Impact of nutrition on brain development and its neuroprotective implications following preterm birth. Pediatr Res. 2015; 77 (1-2): 148-155.

  4. Lau C. Development of infant oral feeding skills: what do we know? Am J Clin Nutr. 2016; 103 (2): 616S-621S.

  5. Rodríguez-Bonito R, Rodríguez-Balderrama I. Manual de neonatología. 2a edición. México: McGraw-Hill/Interamericana; 2012. pp. 75-84.

  6. Kuschel CA, Harding JE. Fat supplementation of human milk for promoting growth in preterm infants. Cochrane Database Syst Rev. 2000; (2): CD000341. doi: 10.1002/14651858.CD000341.

  7. Martin CR. Lipids and fatty acids in the preterm infant, part 1: Basic mechanisms of delivery, hydrolysis, and availability. NeoReviews. 2015; 16 (3): c160-c68.

  8. Koletzko B, Poindexter B, Uauy R. Nutritional care of preterm infants. Basel: Karger; 2014. pp. 82-98.

  9. Fenton TR, McMillan DD, Sauve RS. Nutrition and growth analysis of very low birth weight infants. Pediatrics. 1990; 86: 378-383.

  10. Giuliani F, Cheikh Ismail L, Bertino E, Bhutta ZA, Ohuma EO, Rovelli I et al. Monitoring postnatal growth of preterm infants: present and future. Am J Clin Nutr. 2016; 103 (2): 635S-47S.

  11. Pereira-da-Silva L, Virella D, Fusch C. Nutritional assessment in preterm infants: a practical approach in the NICU. Nutrients. 2019; 11 (9): 1999.

  12. Joshi S, Jain N. To compare the efficacy of fortification of expressed breast milk with medium chain triglycerides and coconut oil on the physical growth of very low birth weight babies. Int J Pediatr Res. 2018; 5 (9): 432-440.




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