2022, Number 4
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Rev CONAMED 2022; 27 (4)
Effectiveness of vaccines against COVID-19 applied to health personnel
Hernández PF, Martínez SVN, Aparicio BMM
Language: Spanish
References: 23
Page: 167-174
PDF size: 117.40 Kb.
ABSTRACT
Introduction: vaccines against COVID-19 have already proven their efficacy, but their effectiveness is still unknown.
Objective: to determine the effectiveness of the different vaccines in health personnel to prevent COVID-19.
Material and methods: cohort study. All health personnel vaccinated against SARS-CoV-2 and who treated patients with COVID-19 were considered and compared with unvaccinated health personnel. Were questioned about the diagnosis of COVID-19 corroborated by PCR or antigen testing, and its complications. Statistical analysis: for the determination of effectiveness, the formula: EV = (1 - OR) × 100.
Results: 340 health workers were studied; 325 vaccinated and 15 unvaccinated. Of 325 vaccinated with the first dose, 8 were positive for SARS-CoV-2, second dose, 35 of 286 and booster in 272, 50 tested positive, 4 of 15 unvaccinated tested positive. The effectiveness for the first dose was 97.5%, the second 95.2% and the booster 9.91%.
Conclusions: the effectiveness of the vaccine against mild COVID-19 in health personnel vaccinated in the first dose is high, it decreases a little for the 2nd dose but drops dramatically for the booster to only 9.91%.
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