medigraphic.com
ISSN 0326-3428 (Print)
Órgano de difusión científica de la Asociación Nefrológica de Buenos Aires

2021, Number 4

<< Back Next >>

Rev Nefrol Dial Traspl 2021; 41 (4)

Impact of COVID-19 on brain death and organ donation; a single center study in Turkey

Kılınc G, Coken F

Language: English
References: 27
Page: 257-263
PDF size: 246.79 Kb.


ABSTRACT

Objectives: More than 50 million people in the world have been diagnosed with COVID-19 and more than 1 million 250 thousand patients have died. With the increasing number of COVID-19 patients admitted to hospitals, problems related to non- COVID-19 patient care have emerged. Organ transplant organizations have had to adapt to this difficult time. The current and long-term impact due to the COVID-19 pandemic is an important factor to be taken into account. An important question to ask is how this outbreak has changed the organ donation process and how long it will take to address a potentially growing waiting list. Methods: We analized the effects of the pandemic COVID-19 in 2020 inTurkey between March and May. We have counted the number of brain deaths and organ donations in these months. We retrospectively compared the same months in 2019, the months before and after the pandemic in 2020, and the years 2019-2020.Results: When examined in other months, it is seen that the effect of the pandemic on brain death and organ donation continues not only in the months when the pandemic is intense, but also in other months. The total number of brain deaths in 2019 was 37, and family donations were 22; In 2020, the number of brain deaths decreased to 13, and family donations decreased to 7. This corresponds to a decrease of 64.86% and 68.18%, respectively, compared to the previous year.Conclusions: Brain death, organ donation and organ transplantation have decreased significantly with the onset of the pandemic compared to the previous years and the pre-pandemic period. Studies from different countries and regions have also shown that this decrease becomes even more pronounced where the number of cases is high.


REFERENCES

  1. Fauci AS, Lane HC, Redfield RR. COVID-19- Navigating the uncharted. N Engl J Med. 2020;382(13):1268-9. doi: 10.1056/NEJMe2002387.

  2. Gorbalenya AE, Baker SC, Baric RS, et al. Severeacute respiratory syndrome-related coronavirus: Thespecies and its viruses – a statement of the CoronavirusStudy Group [Preprint]. bioRxiv; feb. 2020. doi:10.1101/2020.02.07.937862.

  3. Phelan AL, Katz R, Gostin LO. The novel coronavirusoriginating in Wuhan, China: challenges for globalhealth governance. JAMA. 2020;323(8):709-10. doi:10.1001/jama.2020.1097.

  4. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, etal. Clinical features of patients infected with 2019novel coronavirus in Wuhan, China. The Lancet.2020;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5.

  5. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinicalcourse and risk factors for mortality of adult inpatientswith COVID-19 in Wuhan, China: a retrospectivecohort study. Lancet. 2020;395(10229):1054-62. doi:10.1016/S0140-6736(20)30566-3.

  6. Cirrincione L, Plescia F, Ledda C, Rapisarda V,Martorana D, Moldovan RE, et al. COVID-19Pandemic: prevention and protection measuresto be adopted at the workplace. Sustainability.2020;12(9):1-18. doi: 10.3390/su12093603.

  7. World Health Organization. WHO Coronavirus(COVID-19) Dashboard [Internet]. Disponible en: (consulta: 17/12/2020).

  8. 8.) Sağlık Bakanlığı TC. Genel Koronavirüs Tablosu[Internet]. Disponible en: (consulta: 17/12/2020).

  9. Kumar D, Manuel O, Natori Y, Egawa H, Grossi P,Han SH, Fernández-Ruiz M, Humar A. COVID-19: Aglobal transplant perspective on successfully navigatinga pandemic. Am J Transplant. 2020;20(7):1773-9. doi:10.1111/ajt.15876.

  10. Martino F, Plebani M, Ronco C. Kidney transplantprogrammes during the COVID-19 pandemic. LancetRespir Med. 2020;8(5):e39. doi: 10.1016/S2213-2600(20)30182-X.

  11. Halazun KJ, Rosenblatt R. Lest we forget. AmJ Transplant. 2020;20(7):1785-6. doi: 10.1111/ajt.15888.

  12. Wall AE, Pruett T, Stock P, Testa G. Coronavirusdisease 2019: utilizing an ethical framework forrationing absolutely scarce health-care resources intransplant allocation decisions. Am J Transplant.2020;20(9):2332-6. doi: 10.1111/ajt.15914.

  13. Levin A, Tonelli M, Bonventre J, Coresh J, DonnerJA, Fogo AB, et al; ISN Global Kidney HealthSummit participants. Global kidney health 2017 andbeyond: a roadmap for closing gaps in care, research,and policy. Lancet. 2017;390(10105):1888-917. doi:10.1016/S0140-6736(17)30788-2.

  14. American Society of Transplantation. COVID-19Resources for Transplant Community [Internet].Disponible en: (consulta: 17/07/2020).

  15. Loupy A, Aubert O, Reese PP, Bastien O,Bayer F, Jacquelinet C. Organ procurement andtransplantation during the COVID-19 pandemic.Lancet. 2020;395(10237):e95-e96. doi: 10.1016/S0140-6736(20)31040-0.

  16. Ravanan R, Callaghan CJ, Mumford L, Ushiro-Lumb I, Thorburn D, Casey J, et al. SARS-CoV-2infection and early mortality of waitlisted and solidorgan transplant recipients in England: A nationalcohort study. Am J Transplant. 2020;20(11):3008-18.doi: 10.1111/ajt.16247.

  17. Brindle ME, Gawande A. Managing COVID-19 insurgical systems. Ann Surg. 2020;272(1):e1-e2. doi:10.1097/SLA.0000000000003923.

  18. Manara AR, Mumford L, Callaghan CJ, Ravanan R,Gardiner D. Donation and transplantation activityin the UK during the COVID-19 lockdown. Lancet.2020;396(10249):465-6. doi: 10.1016/S0140-6736(20)31692-5.

  19. de Vries APJ, Alwayn IPJ, Hoek RAS, van denBerg AP, Ultee FCW, Vogelaar SM, et al. Immediateimpact of COVID-19 on transplant activity in theNetherlands. Transpl Immunol. 2020;61:101304. doi:10.1016/j.trim.2020.101304.

  20. Domínguez-Gil B, Coll E, Ferrer-Fàbrega J, BriceñoJ, Ríos A. Dramatic impact of the COVID-19outbreak on donation and transplantation activitiesin Spain. Cir Esp (Engl Ed). 2020;98(7):412-4. doi:10.1016/j.ciresp.2020.04.012.

  21. Roza BA, Mendes KDS. The Coronavirus pandemicand the impact on donation and transplantationin Brazil. Prog Transplant. 2020;30(3):292-3. doi:10.1177/1526924820935413.

  22. Angelico R, Trapani S, Manzia TM, Lombardini L,Tisone G, Cardillo M. The COVID-19 outbreak inItaly: Initial implications for organ transplantationprograms. Am J Transplant. 2020;20(7):1780-4. doi:10.1111/ajt.15904.

  23. Cannavò A, Passamonti SM, Martinuzzi D,Longobardi A, Fiorattini A, Troni NM, et al. Theimpact of COVID-19 on solid organ donation:the North Italy Transplant Program Experience.Transplant Proc. 2020;52(9):2578-83. doi: 10.1016/j.transproceed.2020.06.025.

  24. Moris D, Shaw BI, Dimitrokallis N, Barbas AS.Organ donation during the coronavirus pandemic:an evolving saga in uncharted waters. Transpl Int.2020;33(7):826-7. doi: 10.1111/tri.13614.

  25. Neidlinger NA, Smith JA, D’Alessandro AM, RoeD, Taber TE, Pereira MR, et al. Organ recovery fromdeceased donors with prior COVID-19: a case series.Transpl Infect Dis. 2021;23(2):e13503. doi: 10.1111/tid.13503.

  26. Ting J, Wong YL. Challenges in organ donation duringCOVID-19 pandemic: a Singapore perspective. Int JTransplant Res Med. 2020;6:53. doi: 10.23937/2572-4045.1510053.

  27. Shah MB, Lynch RJ, El-Haddad H, Doby B,Brockmeier D, Goldberg DS. Utilization of deceaseddonors during a pandemic: argument against usingSARS-CoV-2-positive donors. Am J Transplant.2020;20(7):1795-9. doi: 10.1111/ajt.15969.




2020     |     www.medigraphic.com