2022, Number 4
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Medicina & Laboratorio 2022; 26 (4)
Cutaneous photoaging and its association with skin cancer: a systematic review
Delgado-Villacis CH, Calvo-Betancur VD, Escobar-Franco MM
Language: Spanish
References: 32
Page: 335-351
PDF size: 114.03 Kb.
ABSTRACT
Introduction. A fundamental factor in skin aging is cumulative exposure
to sunlight. As the photoaging process progresses, collagen and elastic fibers experience
greater damage, generating pathologies associated with cancer. The aim
of this review is to analyze the evidence that exists in relation to the different situations
of cutaneous photoaging and its association with skin cancer.
Methodology.
A systematic, exploratory review was prepared through a bibliographic search in
database managers in health. A total of 18 articles were selected between the years
2019 and 2020.
Results. The articles information were grouped into two matrix, the
first one that indicates the main themes of photoaging and the relationship with
the factors associated with skin cancer, and a second matrix that presents the interrelationship
of these factors with the most relevant conclusion of the study.
Conclusions.
Photoaging is a problem that grows day by day impacting on human life,
creating repercussions on a physical and mental level affecting the quality of life.
It is necessary to raise awareness about photoprotection mechanisms such as the
use of sunscreen, antioxidants , avoid sunlight, use of solar lenses, among others;
and in cases where there is already some damage caused by photoaging, choose
the best alternative and individualize each patient according to their skin type and
diseases associated with age, for a better treatment approach, and thus positively
impact the exponential growth that exists today in various types of skin cancer and
precancerous lesions.
REFERENCES
James WD, Elston D, Treat JR, RosenbachMA, Neuhaus I. Chapter 1. Skin: Basic structureand function. Andrews’ diseases of the skin:Clinical dermatology. 13th ed. Philadelphia:Saunders Elsevier; 2019. p. e1-10.
Rünger TM. Section thirteen: Disorders dueto physical agents. Ultraviolet light. In: BologniaJL, Schaffer JV, Cerroni L, eds. Dermatology:2-volume set. 4th ed. Amsterdam, Netherlands:Elsevier; 2018. p. 1.536
González-Púmariega M, Vernhes-Tamayo M,Sánchez-Lamar Á. La radiación ultravioleta. Suefecto dañino y consecuencias para la salud humana.Theoria 2009;18:69-80.
Wesley NO, Rohrer TE. Section twenty-two: Cosmeticsurgery. Evaluation of beauty and the agingface. In: Bolognia JL, Schaffer JV, Cerroni L, eds.Dermatology: 2-volume set. 4th ed. Amsterdam,Netherlands: Elsevier; 2018. p. 1.536.
Soyer HP, Rigel DS, McMeniman E. Sectioneighteen: Neoplasms of the skin. Actinic keratosis,basal cell carcinoma and squamous cell carcinoma.In: Bolognia JL, Schaffer JV, Cerroni L, eds.Dermatology: 2-volume set. 4th ed. Amsterdam,Netherlands: Elsevier; 2018. p. 1.872.
DeWane ME, Kelsey A, Oliviero M, RabinovitzH, Grant-Kels JM. Melanoma on chronically sundamagedskin: Lentigo maligna and desmoplasticmelanoma. J Am Acad Dermatol 2019;81:823-833. https://doi.org/10.1016/j.jaad.2019.03.066.
Ostrowski SM, Fisher DE. Biology of melanoma.Hematol Oncol Clin North Am 2021;35:29-56.https://doi.org/10.1016/j.hoc.2020.08.010.
Fernández-Figueras MT. Clasificación WHO delesiones melanocíticas. Piel 2020;35:141-145.https://doi.org/10.1016/j.piel.2019.10.002.
Leccia MT, Lebbe C, Claudel JP, Narda M,Basset-Seguin N. New vision in photoprotectionand photorepair. Dermatol Ther (Heidelb)2019;9:103-115. https://doi.org/10.1007/s13555-019-0282-5.
Saginala K, Barsouk A, Aluru JS, Rawla P,Barsouk A. Epidemiology of melanoma. MedSci 2021;9:63. https://doi.org/10.3390/medsci9040063.
Chien AL, Qi J, Grandhi R, Kim N, César SSA,Harris-Tryon T, et al. Effect of age, gender, andsun exposure on ethnic skin photoaging: evidencegathered using a new photonumeric scale. JNatl Med Assoc 2018;110:176-181. https://doi.org/10.1016/j.jnma.2017.05.001.
Lui H, Richer V. Section twenty: Physicaltreatment modalities. Photodynamic therapy. In:Bolognia JL, Schaffer JV, L C, eds. Dermatology:2-volume set. 4th ed. Amsterdam, Netherlands:Elsevier; 2018. p. 2.341.
Saurat J-H, Sorg O. Section nineteen: Medicaltherapy. Retinoids. In: Bolognia JL SJ, CerroniL,, ed. Dermatology: 2-volume set. 4th ed: Amsterdam,Netherlands; 2018. p. 2.200.
Vincent A. Section nineteen: Medical therapy.Sunscreens and photoprotection. In: BologniaJL, Schaffer JV, Cerroni L, eds. Dermatology:2-volume set. 4th ed. Amsterdam, Netherlands:Elsevier; 2018. p. 2.310.
Castillo-Morales J, Villegas-Baldomero L. Revisiónsistemática: efectividad de las intervencionespara disminuir y controlar la obesidady el sobrepeso en la población infantil 2000 a2012. [Trabajo de grado Especialización en Epidemiología].Bogotá: Universidad CES-Universidaddel Rosario 2012.
Fuentes-Lorenzo JL. Las plantas como fuentede compuestos fotoprotectores frente al dañoen el ADN producido por la radiación ultravioleta.Rev Acad Colomb Cienc Exact Fis Nat2019;43:550-562. https://doi.org/https://doi.org/10.18257/raccefyn.841.
Bocheva G, Slominski RM, Slominski AT.Neuroendocrine aspects of skin aging. Int J MolSci 2019;20:2798. https://doi.org/10.3390/ijms20112798.
Shanbhag S, Nayak A, Narayan R, Nayak UY.Anti-aging and sunscreens: paradigm shift incosmetics. Adv Pharm Bull 2019;9:348-359.https://doi.org/10.15171/apb.2019.042.
Wang M, Charareh P, Lei X, Zhong JL. Autophagy:Multiple mechanisms to protect skinfrom ultraviolet radiation-driven photoaging.Oxid Med Cell Longev 2019;2019:8135985.https://doi.org/10.1155/2019/8135985.
Shin JW, Kwon SH, Choi JY, Na JI, Huh CH,Choi HR, et al. Molecular mechanisms of dermalaging and antiaging approaches. Int J MolSci 2019;20:2126. https://doi.org/10.3390/ijms20092126.
Bi Y, Xia H, Li L, Lee RJ, Xie J, Liu Z, et al. Liposomalvitamin D(3) as an anti-aging agent forthe skin. Pharmaceutics 2019;11:311. https://doi.org/10.3390/pharmaceutics11070311.
Choi EH. Aging of the skin barrier. Clin Dermatol2019;37:336-345. https://doi.org/10.1016/j.clindermatol.2019.04.009.
Singer S, Karrer S, Berneburg M. Modernsun protection. Curr Opin Pharmacol2019;46:24-28. https://doi.org/10.1016/j.coph.2018.12.006.
Zouboulis CC, Hoenig LJ. Skin aging revisited.Clin Dermatol 2019;37:293-295. https://doi.org/10.1016/j.clindermatol.2019.04.012.
Gupta V, Sharma VK. Skin typing: Fitzpatrickgrading and others. Clin Dermatol2019;37:430-436. https://doi.org/10.1016/j.clindermatol.2019.07.010.
Strnadova K, Sandera V, Dvorankova B, KodetO, Duskova M, Smetana K, et al. Skinaging: the dermal perspective. Clin Dermatol2019;37:326-335. https://doi.org/10.1016/j.clindermatol.2019.04.005.
Yeager DG, Lim HW. What's new in photoprotection:A review of new concepts and controversies.Dermatol Clin 2019;37:149-157.https://doi.org/10.1016/j.det.2018.11.003.
Venkatesh S, Maymone MBC, VashiNA. Aging in skin of color. Clin Dermatol2019;37:351-357. https://doi.org/10.1016/j.clindermatol.2019.04.010.
Reinehr CPH, Bakos RM. Actinic keratoses: reviewof clinical, dermoscopic, and therapeuticaspects. An Bras Dermatol 2019;94:637-657.https://doi.org/10.1016/j.abd.2019.10.004.
Bellei B, Picardo M. Premature cell senescencein human skin: Dual face in chronic acquiredpigmentary disorders. Ageing Res Rev2020;57:100981. https://doi.org/10.1016/j.arr.2019.100981.
Gu Y, Han J, Jiang C, Zhang Y. Biomarkers,oxidative stress and autophagy in skin aging.Ageing Res Rev 2020;59:101036. https://doi.org/10.1016/j.arr.2020.101036.
Georgakopoulou EA, Valsamidi C, VeroutisD, Havaki S. The bright and dark side of skinsenescence. Could skin rejuvenation antisenescenceinterventions become a "bright"new strategy for the prevention of age-relatedskin pathologies? Mech Ageing Dev2021;193:111409. https://doi.org/10.1016/j.mad.2020.111409.