2004, Number 1
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Arch Cardiol Mex 2004; 74 (1)
Assessment of diastolic function in Chagas’disease with pulsed Doppler tissue imaging
Migliore RA, Adaniya ME, Tamagusuku H, Lapuente A
Language: Spanish
References: 31
Page: 31-38
PDF size: 125.11 Kb.
ABSTRACT
Diastolic function is involved early during
the undetermined form of Chagas’disease (Ch). Pulsed Doppler tissue imaging (DTI)
is a new technique to evaluate diastolic function recording myocardial velocities
in the longitudinal axis. To evaluate the relevance of DTI in patients with Ch,
we studied, with Doppler and echocardiography, 49 patients (average age 49 ±
12 years) and 20 normal subjects (average age 45 ± 15 years) as a control
group (C). Patients were divided in four groups according to the pattern of their
mitral and pulmonary vein flows: Normal diastolic function (N), prolonged relaxation
(PR), pseudonormal (PN) and restrictive (R). Peak velocity of the E wave of the
lateral mitral annulus (Ea) was diminished in PR, PN, and R patients (0.11 ±
0.02 m/s, 0.10 ± 0.02 m/s and 0.12 ± 0.06 m/s, respectively) as compared
to group C (0.18 ± 0.07 m/s, p < 0.01) but not with respect to group N
(0.15 ± 0.03 m/s, N.S.). In this latter group only peak E velocity of transmitral
flow/Ea ratio was useful to detect diastolic abnormalities as compared to group
C (4.92 ± 0.98
vs 4.14 ± 1.26, p < 0.05). DTI was useful in
the assessment of diastolic function in Ch, including those patients in whom mitral
and pulmonary vein flows were normal.
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